null
SMILES: Cn1cc(-c2cccc(NS(=O)(=O)c3cccc(Cl)c3)c2F)c2c(N)ncnc12
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Eukaryotic translation initiation factor 2-alpha kinase 3 [540-1115] (Homo sapiens (Human)) | BDBM580481 (US11491158, Cmpd 13) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The biochemical activity of compounds was determined by incubation with PERK recombinant enzyme (cytoplasmic domain corresponding to residues 540-111... | Citation and Details BindingDB Entry DOI: 10.7270/Q2C2518M | |||||||||||
More data for this Ligand-Target Pair |