BDBM58334 (5Z)-2-(4-ethylanilino)-5-(4-hydroxy-3,5-dimethoxy-benzylidene)-2-thiazolin-4-one::(5Z)-2-(4-ethylanilino)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-1,3-thiazol-4-one::(5Z)-2-(4-ethylanilino)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-4-thiazolone::(5Z)-5-[(3,5-dimethoxy-4-oxidanyl-phenyl)methylidene]-2-[(4-ethylphenyl)amino]-1,3-thiazol-4-one::2-(4-Ethyl-phenylimino)-5-(4-hydroxy-3,5-dimethoxy-benzylidene)-thiazolidin-4-one::MLS001211833::SMR000517247::cid_1938996
SMILES: CCc1ccc(NC2=NC(=O)C(S2)=Cc2cc(OC)c(O)c(OC)c2)cc1
InChI Key: InChIKey=MDHXRSDCPWIQIZ-UHFFFAOYSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
streptokinase A precursor (Streptococcus pyogenes M1 GAS) | BDBM58334![]() ((5Z)-2-(4-ethylanilino)-5-(4-hydroxy-3,5-dimethoxy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
drug resistance protein 1 (Candida albicans) | BDBM58334![]() ((5Z)-2-(4-ethylanilino)-5-(4-hydroxy-3,5-dimethoxy...) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 6.05E+3 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description UNMCMD Assay Overview: Assay Support: 1 R03 MH087406-01A1 Project Title: Identification of broad-spectrum antifungal efflux pump inhibitors ... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q24M932M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
drug resistance protein 2 (Candida albicans) | BDBM58334![]() ((5Z)-2-(4-ethylanilino)-5-(4-hydroxy-3,5-dimethoxy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 1.92E+4 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description UNMCMD Assay Overview: Assay Support: 1 R03 MH087406-01A1 Project Title: Identification of broad-spectrum antifungal efflux pump inhibitors ... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q28C9TSJ | |||||||||||
More data for this Ligand-Target Pair |