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SMILES: Cc1noc(C)c1-c1cc(Cl)c(Nc2ccccc2C(O)=O)c(Cl)c1

InChI Key:

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 589235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human))	BDBM589235 (US11555009, Compound 15 | US11555009, Compound 29) Show SMILES Cc1noc(C)c1-c1cc(Cl)c(Nc2ccccc2C(O)=O)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The present invention provides a novel class of demethylase FTO inhibitors which inhibit FTO protein activity at very low concentration (typically IC...				Citation and Details
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human))	BDBM589235 (US11555009, Compound 15 | US11555009, Compound 29) Show SMILES Cc1noc(C)c1-c1cc(Cl)c(Nc2ccccc2C(O)=O)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The present invention provides a novel class of demethylase FTO inhibitors which inhibit FTO protein activity at very low concentration (typically IC...				Citation and Details
					More data for this Ligand-Target Pair				3D Structure (crystal)