BindingDB PrimarySearch

null

SMILES: CCCOc1cc(ccc1OC(F)F)-c1cncc(c1)C1COB(O)C1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589754
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589754 (US11559538, Example 17 \| US11559538, Example 50) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interleukin-13 (Human)	BDBM589754 (US11559538, Example 17 \| US11559538, Example 50) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589754 (US11559538, Example 17 \| US11559538, Example 50) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589754 (US11559538, Example 17 \| US11559538, Example 50) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.52	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM589754 (US11559538, Example 17 \| US11559538, Example 50) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...				Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interleukin-13 (Human)	BDBM589754 (US11559538, Example 17 \| US11559538, Example 50) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	234	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interleukin-4 (Human)	BDBM589754 (US11559538, Example 17 \| US11559538, Example 50) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.04	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair
Interferon gamma receptor 1 (Homo sapiens (Human))	BDBM589754 (US11559538, Example 17 \| US11559538, Example 50) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2542SHJ
TBA					More data for this Ligand-Target Pair