null

SMILES: Cc1cc(CC(=O)N[C@H]2CC[C@H](CCN3CCc4nc(OCC(C)(F)F)sc4CC3)CC2)on1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 593769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens)	BDBM593769 (US11578084, Compound I-052) Show SMILES Cc1cc(CC(=O)N[C@H]2CC[C@H](CCN3CCc4nc(OCC(C)(F)F)sc4CC3)CC2)on1 |r,wU:11.11,wD:8.7,(12.95,2.77,;11.41,2.77,;10.5,4.02,;9.04,3.54,;7.7,4.31,;6.37,3.54,;6.37,2,;5.04,4.31,;3.7,3.54,;2.37,4.31,;1.04,3.54,;1.04,2,;-.3,1.23,;-1.63,2,;-2.97,1.23,;-4.32,1.96,;-5.74,1.36,;-6.15,-.19,;-7.61,-.67,;-7.61,-2.21,;-8.95,-2.98,;-10.28,-2.21,;-11.61,-2.98,;-12.95,-2.21,;-12.38,-4.31,;-10.84,-4.31,;-6.15,-2.69,;-5.24,-1.44,;-3.7,-1.44,;-2.69,-.28,;2.37,1.23,;3.7,2,;9.04,2,;10.5,1.53,)| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CF9V1Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM593769 (US11578084, Compound I-052) Show SMILES Cc1cc(CC(=O)N[C@H]2CC[C@H](CCN3CCc4nc(OCC(C)(F)F)sc4CC3)CC2)on1 |r,wU:11.11,wD:8.7,(12.95,2.77,;11.41,2.77,;10.5,4.02,;9.04,3.54,;7.7,4.31,;6.37,3.54,;6.37,2,;5.04,4.31,;3.7,3.54,;2.37,4.31,;1.04,3.54,;1.04,2,;-.3,1.23,;-1.63,2,;-2.97,1.23,;-4.32,1.96,;-5.74,1.36,;-6.15,-.19,;-7.61,-.67,;-7.61,-2.21,;-8.95,-2.98,;-10.28,-2.21,;-11.61,-2.98,;-12.95,-2.21,;-12.38,-4.31,;-10.84,-4.31,;-6.15,-2.69,;-5.24,-1.44,;-3.7,-1.44,;-2.69,-.28,;2.37,1.23,;3.7,2,;9.04,2,;10.5,1.53,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.06HO (20909-55, Naca...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CF9V1Q
					More data for this Ligand-Target Pair