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SMILES: C[C@H](NC(=O)[C@H]1C[C@H](Cc2cccc(C)c2)CN1)C(=O)NCc1cnc2n(C)cc(Cl)c2c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 595388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595388 (US11584714, Compound 1476) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2cccc(C)c2)CN1)C(=O)NCc1cnc2n(C)cc(Cl)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595388 (US11584714, Compound 1476) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2cccc(C)c2)CN1)C(=O)NCc1cnc2n(C)cc(Cl)c2c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
thrombin (Homo sapiens (Human))	BDBM595388 (US11584714, Compound 1476) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2cccc(C)c2)CN1)C(=O)NCc1cnc2n(C)cc(Cl)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair