BindingDB PrimarySearch

null

SMILES: NS(=O)(=O)c1ccc(Nc2ncc3cc4C(O)NC(=O)C5(CCCCC5)n4c3n2)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 601933
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM601933 (4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0MGD
TBA				More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM601933 (4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0MGD
TBA				More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM601933 (4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0MGD
TBA				More data for this Ligand-Target Pair
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Homo sapiens (Human))	BDBM601933 (4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0MGD
TBA				More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM601933 (4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0MGD
TBA				More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM601933 (4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0MGD
TBA				More data for this Ligand-Target Pair
Cyclin-dependent kinase 3/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM601933 (4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0MGD
TBA				More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM601933 (4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0MGD
TBA				More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM601933 (4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0MGD
TBA				More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM601933 (4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0MGD
TBA				More data for this Ligand-Target Pair