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SMILES: COCCNC(=O)c1ccc(cn1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608982   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608982 (US11702409, Example 64a | US11702409, Example 64b) Show SMILES COCCNC(=O)c1ccc(cn1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12 |(9.67,-6.4,;9.28,-4.91,;7.79,-4.51,;7.39,-3.02,;5.9,-2.63,;4.81,-3.71,;5.13,-5.22,;3.35,-3.24,;2.2,-4.27,;.74,-3.79,;.42,-2.29,;1.56,-1.26,;3.03,-1.73,;-1.05,-1.81,;-1.52,-.35,;-3.06,-.35,;-3.83,.99,;-5.32,1.39,;-4.92,2.87,;-3.43,2.48,;-6.41,3.27,;-6.01,4.76,;-4.52,4.36,;-7.1,5.85,;-6.7,7.34,;-8.59,5.45,;-9.67,6.54,;-3.54,-1.81,;-5,-2.29,;-2.29,-2.72,;-2.29,-4.26,;-3.62,-5.03,;-4.96,-4.26,;-3.62,-6.57,;-4.96,-7.34,;-2.29,-7.34,;-.96,-6.57,;.51,-7.04,;1.41,-5.8,;.51,-4.55,;-.96,-5.03,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608982 (US11702409, Example 64a | US11702409, Example 64b) Show SMILES COCCNC(=O)c1ccc(cn1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12 |(9.67,-6.4,;9.28,-4.91,;7.79,-4.51,;7.39,-3.02,;5.9,-2.63,;4.81,-3.71,;5.13,-5.22,;3.35,-3.24,;2.2,-4.27,;.74,-3.79,;.42,-2.29,;1.56,-1.26,;3.03,-1.73,;-1.05,-1.81,;-1.52,-.35,;-3.06,-.35,;-3.83,.99,;-5.32,1.39,;-4.92,2.87,;-3.43,2.48,;-6.41,3.27,;-6.01,4.76,;-4.52,4.36,;-7.1,5.85,;-6.7,7.34,;-8.59,5.45,;-9.67,6.54,;-3.54,-1.81,;-5,-2.29,;-2.29,-2.72,;-2.29,-4.26,;-3.62,-5.03,;-4.96,-4.26,;-3.62,-6.57,;-4.96,-7.34,;-2.29,-7.34,;-.96,-6.57,;.51,-7.04,;1.41,-5.8,;.51,-4.55,;-.96,-5.03,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair