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SMILES: Cc1c(c(nn1C1CC2(C1)CN(C2)C(=O)C=C)-c1ccccc1)-c1c(Cl)c(C)cc2[nH]nc(N)c12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608994 (US11702409, Example 70a | US11702409, Example 70b) Show SMILES Cc1c(c(nn1C1CC2(C1)CN(C2)C(=O)C=C)-c1ccccc1)-c1c(Cl)c(C)cc2[nH]nc(N)c12 |(-2.19,-2.79,;-.73,-2.31,;.52,-3.21,;1.77,-2.31,;1.29,-.84,;-.25,-.84,;-1.15,.4,;-.91,1.92,;-2.43,2.16,;-2.68,.64,;-2.19,3.68,;-3.72,3.93,;-3.96,2.4,;-4.62,5.17,;-6.16,5.17,;-3.92,6.54,;-4.76,7.83,;3.23,-2.79,;3.55,-4.29,;5.02,-4.77,;6.16,-3.74,;5.84,-2.23,;4.38,-1.75,;.52,-4.75,;1.85,-5.52,;3.34,-5.13,;1.85,-7.06,;3.19,-7.83,;.52,-7.83,;-.81,-7.06,;-2.28,-7.54,;-3.18,-6.29,;-2.28,-5.05,;-2.75,-3.58,;-.81,-5.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608994 (US11702409, Example 70a | US11702409, Example 70b) Show SMILES Cc1c(c(nn1C1CC2(C1)CN(C2)C(=O)C=C)-c1ccccc1)-c1c(Cl)c(C)cc2[nH]nc(N)c12 |(-2.19,-2.79,;-.73,-2.31,;.52,-3.21,;1.77,-2.31,;1.29,-.84,;-.25,-.84,;-1.15,.4,;-.91,1.92,;-2.43,2.16,;-2.68,.64,;-2.19,3.68,;-3.72,3.93,;-3.96,2.4,;-4.62,5.17,;-6.16,5.17,;-3.92,6.54,;-4.76,7.83,;3.23,-2.79,;3.55,-4.29,;5.02,-4.77,;6.16,-3.74,;5.84,-2.23,;4.38,-1.75,;.52,-4.75,;1.85,-5.52,;3.34,-5.13,;1.85,-7.06,;3.19,-7.83,;.52,-7.83,;-.81,-7.06,;-2.28,-7.54,;-3.18,-6.29,;-2.28,-5.05,;-2.75,-3.58,;-.81,-5.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair