Found 14 hits for monomerid = 621125 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Interleukin-1 receptor-associated kinase 1
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| UniChem
| | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| UniChem
| | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| UniChem
| | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.0410 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [572-603]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.910 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [F691L]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [K663Q]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.330 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [N841I]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [R834Q]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| UniChem
| | n/a | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |