BDBM65510 CPZ analog, 4

SMILES: OS(=O)(=O)CCCCCN1c2ccccc2Sc2ccc(Cl)cc12

InChI Key: InChIKey=FKUGMGRFWHLRJB-UHFFFAOYSA-N

Data: 1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 65510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit alpha type-6 (Homo sapiens (Human))	BDBM65510 (CPZ analog, 4) Show SMILES OS(=O)(=O)CCCCCN1c2ccccc2Sc2ccc(Cl)cc12 Show InChI InChI=1S/C17H18ClNO3S2/c18-13-8-9-17-15(12-13)19(10-4-1-5-11-24(20,21)22)14-6-2-3-7-16(14)23-17/h2-3,6-9,12H,1,4-5,10-11H2,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	7.5	37
Michigan State University					Assay Description Activity assays were carried out in a 200 uL reaction volume. Different concentrations of test compounds were added to a black flat/clear bottom 96-w...				ACS Chem Biol 12: 2240-2247 (2017) Article DOI: 10.1021/acschembio.7b00489 BindingDB Entry DOI: 10.7270/Q2DV1H2F
					More data for this Ligand-Target Pair