BDBM65523 (S)-4-(3-(2-((2-fluorophenyl)amino)-2-oxo-1-phenylethyl)ureido)-N-(6-(hydroxyamino)-6-oxohexyl)benzamide (L2)

SMILES: ONC(=O)CCCCCNC(=O)c1ccc(NC(=O)N[C@H](C(=O)Nc2ccccc2F)c2ccccc2)cc1

InChI Key: InChIKey=HZSKMNLWWFOTPC-VWLOTQADSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 65523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM65523 ((S)-4-(3-(2-((2-fluorophenyl)amino)-2-oxo-1-phenyl...) Show SMILES ONC(=O)CCCCCNC(=O)c1ccc(NC(=O)N[C@H](C(=O)Nc2ccccc2F)c2ccccc2)cc1 Show InChI InChI=1S/C28H30FN5O5/c29-22-11-6-7-12-23(22)32-27(37)25(19-9-3-1-4-10-19)33-28(38)31-21-16-14-20(15-17-21)26(36)30-18-8-2-5-13-24(35)34-39/h1,3-4,6-7,9-12,14-17,25,39H,2,5,8,13,18H2,(H,30,36)(H,32,37)(H,34,35)(H2,31,33,38)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Qingdao University					Assay Description The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...				J Enzyme Inhib Med Chem 29: 582-9 (2014) Article DOI: 10.3109/14756366.2013.827678 BindingDB Entry DOI: 10.7270/Q2S46Q3F
					More data for this Ligand-Target Pair