BDBM67404 1-[4-(trifluoromethoxy)phenyl]sulfonyl-2-benzimidazolamine::1-[4-(trifluoromethoxy)phenyl]sulfonylbenzimidazol-2-amine::1-[4-(trifluoromethyloxy)phenyl]sulfonylbenzimidazol-2-amine::MLS-0435748.0001::[1-[4-(trifluoromethoxy)phenyl]sulfonylbenzimidazol-2-yl]amine::cid_45253887

SMILES: Nc1nc2ccccc2n1S(=O)(=O)c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=GAWCQNPYZRKFGL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 67404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
nucleotide-binding oligomerization domain containing 1 (Homo sapiens (Human))	BDBM67404 (1-[4-(trifluoromethoxy)phenyl]sulfonyl-2-benzimida...) Show SMILES Nc1nc2ccccc2n1S(=O)(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C14H10F3N3O3S/c15-14(16,17)23-9-5-7-10(8-6-9)24(21,22)20-12-4-2-1-3-11(12)19-13(20)18/h1-8H,(H2,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	8.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23J3BDQ
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM67404 (1-[4-(trifluoromethoxy)phenyl]sulfonyl-2-benzimida...) Show SMILES Nc1nc2ccccc2n1S(=O)(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C14H10F3N3O3S/c15-14(16,17)23-9-5-7-10(8-6-9)24(21,22)20-12-4-2-1-3-11(12)19-13(20)18/h1-8H,(H2,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2V1237V
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 2 (Homo sapiens (Human))	BDBM67404 (1-[4-(trifluoromethoxy)phenyl]sulfonyl-2-benzimida...) Show SMILES Nc1nc2ccccc2n1S(=O)(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C14H10F3N3O3S/c15-14(16,17)23-9-5-7-10(8-6-9)24(21,22)20-12-4-2-1-3-11(12)19-13(20)18/h1-8H,(H2,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2ZS2TX1
					More data for this Ligand-Target Pair