BDBM71415 3-(N-ethylanilino)-2H-isoquinolin-1-one::3-(N-ethylanilino)isocarbostyril::3-[ethyl(phenyl)amino]-2H-isoquinolin-1-one::MLS001167171::SMR000641033::cid_4461971

SMILES: CCN(c1ccccc1)c1cc2ccccc2c(=O)[nH]1

InChI Key: InChIKey=JQZQWLUUKUSJKH-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 71415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sentrin-specific protease 6 (Homo sapiens (Human))	BDBM71415 (3-(N-ethylanilino)-2H-isoquinolin-1-one | 3-(N-eth...) Show SMILES CCN(c1ccccc1)c1cc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C17H16N2O/c1-2-19(14-9-4-3-5-10-14)16-12-13-8-6-7-11-15(13)17(20)18-16/h3-12H,2H2,1H3,(H,18,20)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q27H1H10
					More data for this Ligand-Target Pair
Caspase-3 (Homo sapiens (Human))	BDBM71415 (3-(N-ethylanilino)-2H-isoquinolin-1-one | 3-(N-eth...) Show SMILES CCN(c1ccccc1)c1cc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C17H16N2O/c1-2-19(14-9-4-3-5-10-14)16-12-13-8-6-7-11-15(13)17(20)18-16/h3-12H,2H2,1H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2RJ4GZT
					More data for this Ligand-Target Pair
Apoptotic protease-activating factor 1 (Homo sapiens (Human))	BDBM71415 (3-(N-ethylanilino)-2H-isoquinolin-1-one | 3-(N-eth...) Show SMILES CCN(c1ccccc1)c1cc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C17H16N2O/c1-2-19(14-9-4-3-5-10-14)16-12-13-8-6-7-11-15(13)17(20)18-16/h3-12H,2H2,1H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2F18X8S
					More data for this Ligand-Target Pair
Caspase-9 (Homo sapiens (Human))	BDBM71415 (3-(N-ethylanilino)-2H-isoquinolin-1-one | 3-(N-eth...) Show SMILES CCN(c1ccccc1)c1cc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C17H16N2O/c1-2-19(14-9-4-3-5-10-14)16-12-13-8-6-7-11-15(13)17(20)18-16/h3-12H,2H2,1H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q25M647F
					More data for this Ligand-Target Pair
Apoptotic protease-activating factor 1 (Homo sapiens (Human))	BDBM71415 (3-(N-ethylanilino)-2H-isoquinolin-1-one | 3-(N-eth...) Show SMILES CCN(c1ccccc1)c1cc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C17H16N2O/c1-2-19(14-9-4-3-5-10-14)16-12-13-8-6-7-11-15(13)17(20)18-16/h3-12H,2H2,1H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2JS9NZB
					More data for this Ligand-Target Pair
Sentrin-specific protease 8 (Homo sapiens (Human))	BDBM71415 (3-(N-ethylanilino)-2H-isoquinolin-1-one | 3-(N-eth...) Show SMILES CCN(c1ccccc1)c1cc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C17H16N2O/c1-2-19(14-9-4-3-5-10-14)16-12-13-8-6-7-11-15(13)17(20)18-16/h3-12H,2H2,1H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MS3R7H
					More data for this Ligand-Target Pair