BDBM71510 US9546164, 530::US9694002, 529::US9694002, 530

SMILES: CC(C)(N1CCC[C@H](C1)Oc1cc(F)c(cc1C1CC1)C(N)=O)c1cccc(Cl)c1

InChI Key: InChIKey=WGJKXBIAQQOYRR-GOSISDBHSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 71510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium Channel Complex (Homo sapiens (Human))	BDBM71510 (US9546164, 530 | US9694002, 529 | US9694002, 530) Show SMILES CC(C)(N1CCC[C@H](C1)Oc1cc(F)c(cc1C1CC1)C(N)=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C24H28ClFN2O2/c1-24(2,16-5-3-6-17(25)11-16)28-10-4-7-18(14-28)30-22-13-21(26)20(23(27)29)12-19(22)15-8-9-15/h3,5-6,11-13,15,18H,4,7-10,14H2,1-2H3,(H2,27,29)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...				US Patent US9694002 (2017) BindingDB Entry DOI: 10.7270/Q24B2ZFG
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM71510 (US9546164, 530 | US9694002, 529 | US9694002, 530) Show SMILES CC(C)(N1CCC[C@H](C1)Oc1cc(F)c(cc1C1CC1)C(N)=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C24H28ClFN2O2/c1-24(2,16-5-3-6-17(25)11-16)28-10-4-7-18(14-28)30-22-13-21(26)20(23(27)29)12-19(22)15-8-9-15/h3,5-6,11-13,15,18H,4,7-10,14H2,1-2H3,(H2,27,29)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...				US Patent US9546164 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZS4
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM71510 (US9546164, 530 | US9694002, 529 | US9694002, 530) Show SMILES CC(C)(N1CCC[C@H](C1)Oc1cc(F)c(cc1C1CC1)C(N)=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C24H28ClFN2O2/c1-24(2,16-5-3-6-17(25)11-16)28-10-4-7-18(14-28)30-22-13-21(26)20(23(27)29)12-19(22)15-8-9-15/h3,5-6,11-13,15,18H,4,7-10,14H2,1-2H3,(H2,27,29)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...				US Patent US9546164 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZS4
					More data for this Ligand-Target Pair
Sodium Channel Complex (Homo sapiens (Human))	BDBM71510 (US9546164, 530 | US9694002, 529 | US9694002, 530) Show SMILES CC(C)(N1CCC[C@H](C1)Oc1cc(F)c(cc1C1CC1)C(N)=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C24H28ClFN2O2/c1-24(2,16-5-3-6-17(25)11-16)28-10-4-7-18(14-28)30-22-13-21(26)20(23(27)29)12-19(22)15-8-9-15/h3,5-6,11-13,15,18H,4,7-10,14H2,1-2H3,(H2,27,29)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...				US Patent US9694002 (2017) BindingDB Entry DOI: 10.7270/Q24B2ZFG
					More data for this Ligand-Target Pair