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SMILES: COc1ccc(Oc2nc3c(C)cccn3c(=O)c2\C=C(/C#N)C(N)=O)cc1

InChI Key: InChIKey=VFWFOVWGIAMSJQ-JLHYYAGUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75097   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Importin subunit alpha-1


(Homo sapiens (Human))		BDBM75097
PNG
((E)-2-Cyano-3-[2-(4-methoxy-phenoxy)-9-methyl-4-ox...)
Show SMILES COc1ccc(Oc2nc3c(C)cccn3c(=O)c2\C=C(/C#N)C(N)=O)cc1
Show InChI InChI=1S/C20H16N4O4/c1-12-4-3-9-24-18(12)23-19(28-15-7-5-14(27-2)6-8-15)16(20(24)26)10-13(11-21)17(22)25/h3-10H,1-2H3,(H2,22,25)/b13-10+
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PCBioAssay
n/an/an/an/a 6.00E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair