BDBM84750 (3) 1H-1,2,4-triazol-3-yl-anilines

SMILES: FC(F)(F)c1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1

InChI Key: InChIKey=WSKMMKRZESEPDS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 84750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM84750 ((3) 1H-1,2,4-triazol-3-yl-anilines) Show SMILES FC(F)(F)c1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1 Show InChI InChI=1S/C20H14F3N5/c21-20(22,23)14-4-3-5-16(12-14)28-13-25-19(27-28)17-6-1-2-7-18(17)26-15-8-10-24-11-9-15/h1-13H,(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	7.5	25
ChemDiv Inc.					Assay Description In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...				Chem Biol Drug Des 69: 331-7 (2007) Article DOI: 10.1111/j.1747-0285.2007.00507.x BindingDB Entry DOI: 10.7270/Q2DR2T12
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM84750 ((3) 1H-1,2,4-triazol-3-yl-anilines) Show SMILES FC(F)(F)c1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1 Show InChI InChI=1S/C20H14F3N5/c21-20(22,23)14-4-3-5-16(12-14)28-13-25-19(27-28)17-6-1-2-7-18(17)26-15-8-10-24-11-9-15/h1-13H,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	7.5	25
ChemDiv Inc.					Assay Description In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...				Chem Biol Drug Des 69: 331-7 (2007) Article DOI: 10.1111/j.1747-0285.2007.00507.x BindingDB Entry DOI: 10.7270/Q2DR2T12
					More data for this Ligand-Target Pair