Found 5 hits for monomerid = 85573 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 19A1
(Homo sapiens (Human)) | BDBM85573
(7-Hydroxy-flavone, 5h)Show InChI InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)15-9-14(18)13-7-4-11(17)8-16(13)20-15/h2-9,17H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | 37 |
Cardiff University
| Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes. |
J Enzym Inhib 16: 417-24 (2001)
Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM85573
(7-Hydroxy-flavone, 5h)Show InChI InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)15-9-14(18)13-7-4-11(17)8-16(13)20-15/h2-9,17H,1H3 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
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MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description Inhibition of human recombinant ARTD1 by fluorescence assay |
J Med Chem 56: 3507-17 (2013)
Article DOI: 10.1021/jm3018783 BindingDB Entry DOI: 10.7270/Q24M95W6 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)
(Rattus norvegicus (rat)) | BDBM85573
(7-Hydroxy-flavone, 5h)Show InChI InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)15-9-14(18)13-7-4-11(17)8-16(13)20-15/h2-9,17H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Punjabi University
Curated by ChEMBL
| Assay Description Inhibition of rat brain AChE using acetylthiocholine iodide as substrate by spectroscopic method |
Bioorg Med Chem 25: 6273-6285 (2017)
Article DOI: 10.1016/j.bmc.2017.09.012 BindingDB Entry DOI: 10.7270/Q22V2JP6 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM85573
(7-Hydroxy-flavone, 5h)Show InChI InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)15-9-14(18)13-7-4-11(17)8-16(13)20-15/h2-9,17H,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assay |
J Med Chem 56: 3507-17 (2013)
Article DOI: 10.1021/jm3018783 BindingDB Entry DOI: 10.7270/Q24M95W6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM85573
(7-Hydroxy-flavone, 5h)Show InChI InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)15-9-14(18)13-7-4-11(17)8-16(13)20-15/h2-9,17H,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa... |
J Med Chem 56: 3507-17 (2013)
Article DOI: 10.1021/jm3018783 BindingDB Entry DOI: 10.7270/Q24M95W6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |