BDBM85574 7-Hydroxy-flavone, 7

SMILES: CCOC(=O)\C=C\c1ccc(cc1)-c1cc(=O)c2ccc(O)cc2o1

InChI Key: InChIKey=HSMVFHJCOGHULU-BJMVGYQFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 85574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM85574 (7-Hydroxy-flavone, 7) Show SMILES CCOC(=O)\C=C\c1ccc(cc1)-c1cc(=O)c2ccc(O)cc2o1 Show InChI InChI=1S/C20H16O5/c1-2-24-20(23)10-5-13-3-6-14(7-4-13)18-12-17(22)16-9-8-15(21)11-19(16)25-18/h3-12,21H,2H2,1H3/b10-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
					More data for this Ligand-Target Pair