BDBM8623 (4-Pyridylmethylene)indane 12b::4-{[(1Z)-5-methoxy-2,3-dihydro-1H-inden-1-ylidene]methyl}pyridine

SMILES: COc1ccc2\C(CCc2c1)=C/c1ccncc1

InChI Key: InChIKey=VDGYNVYFCLIMOF-RAXLEYEMSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM8623 ((4-Pyridylmethylene)indane 12b | 4-{[(1Z)-5-methox...) Show SMILES COc1ccc2\C(CCc2c1)=C/c1ccncc1 Show InChI InChI=1S/C16H15NO/c1-18-15-4-5-16-13(2-3-14(16)11-15)10-12-6-8-17-9-7-12/h4-11H,2-3H2,1H3/b13-10-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...				J Med Chem 48: 1563-75 (2005) Article DOI: 10.1021/jm0492397 BindingDB Entry DOI: 10.7270/Q2SN075F
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM8623 ((4-Pyridylmethylene)indane 12b | 4-{[(1Z)-5-methox...) Show SMILES COc1ccc2\C(CCc2c1)=C/c1ccncc1 Show InChI InChI=1S/C16H15NO/c1-18-15-4-5-16-13(2-3-14(16)11-15)10-12-6-8-17-9-7-12/h4-11H,2-3H2,1H3/b13-10-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Calcutta Curated by ChEMBL					Assay Description Inhibition of aromatase				Eur J Med Chem 45: 4307-15 (2010) Article DOI: 10.1016/j.ejmech.2010.06.033 BindingDB Entry DOI: 10.7270/Q2MP53GH
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM8623 ((4-Pyridylmethylene)indane 12b | 4-{[(1Z)-5-methox...) Show SMILES COc1ccc2\C(CCc2c1)=C/c1ccncc1 Show InChI InChI=1S/C16H15NO/c1-18-15-4-5-16-13(2-3-14(16)11-15)10-12-6-8-17-9-7-12/h4-11H,2-3H2,1H3/b13-10-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Calcutta Curated by ChEMBL					Assay Description Inhibition of aromatase				Eur J Med Chem 45: 4307-15 (2010) Article DOI: 10.1016/j.ejmech.2010.06.033 BindingDB Entry DOI: 10.7270/Q2MP53GH
					More data for this Ligand-Target Pair