BindingDB logo
myBDB logout

null

SMILES: Fc1ccc(cc1)-c1cc(NC(=O)c2nc(ccc2Nc2cncnc2)C2CC2)on1

InChI Key: InChIKey=JJAUNWZYHYUAOR-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97547   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))		BDBM97547
PNG
(US8470820, 58)
Show SMILES Fc1ccc(cc1)-c1cc(NC(=O)c2nc(ccc2Nc2cncnc2)C2CC2)on1
Show InChI InChI=1S/C22H17FN6O2/c23-15-5-3-14(4-6-15)19-9-20(31-29-19)28-22(30)21-18(26-16-10-24-12-25-11-16)8-7-17(27-21)13-1-2-13/h3-13,26H,1-2H2,(H,28,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 2.45E+3n/an/an/an/a7.5n/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Scintillation proximity assay using human PDE10A.

US Patent US8470820 (2013)


BindingDB Entry DOI: 10.7270/Q2J96501
More data for this
Ligand-Target Pair