BDBM98590 (2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-3-hydroxy-propanoyl]amino]-N-[(4-carbamimidoylphenyl)methyl]butanamide::US8476306, 6.16
SMILES: CC(OCc1ccccc1)[C@H](NC(=O)[C@@H](CO)NS(=O)(=O)Cc1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N
InChI Key: InChIKey=JXDRVTULOVVFJK-KDVIAZGZSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trypsin (Rattus norvegicus) | BDBM98590 ((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 11 | -10.8 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen activator urokinase (Rattus norvegicus) | BDBM98590 ((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 61 | -9.80 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Plasminogen activator urokinase | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombin (Rattus norvegicus) | BDBM98590 ((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 100 | -9.51 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Thrombin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmin (Rattus norvegicus) | BDBM98590 ((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.10E+3 | -8.10 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Plasmin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair |