BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 322.3
BDBM50424147		Wt: 290.3
BDBM50277094		Wt: 232.2
BDBM50277104		Wt: 302.3
BDBM50277107		Wt: 232.2
BDBM50277119
Wt: 258.3
BDBM50277110		Wt: 258.3
BDBM50277102		Wt: 290.3
BDBM50277126		Wt: 276.3
BDBM50277127		Wt: 316.3
BDBM50277125
Wt: 316.3
BDBM50277128		Wt: 252.2
BDBM50403560		Wt: 266.2
BDBM50403561		Wt: 236.2
BDBM50403567		Wt: 254.2
BDBM50403569
Displayed 1 to 15 (of 187 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 15 hits in this display   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-5


(Mus musculus)		BDBM50277125
PNG
(CHEMBL4165527)
Show SMILES OCCCOc1coc2cccc(CC3CCCCC3)c2c1=O
Show InChI InChI=1S/C19H24O4/c20-10-5-11-22-17-13-23-16-9-4-8-15(18(16)19(17)21)12-14-6-2-1-3-7-14/h4,8-9,13-14,20H,1-3,5-7,10-12H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50277126
PNG
(CHEMBL4166115)
Show SMILES CC(C)CCc1cccc2occ(OCCCO)c(=O)c12
Show InChI InChI=1S/C17H22O4/c1-12(2)7-8-13-5-3-6-14-16(13)17(19)15(11-21-14)20-10-4-9-18/h3,5-6,11-12,18H,4,7-10H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50277110
PNG
(CHEMBL4159732)
Show SMILES Oc1coc2cccc(CC3CCCCC3)c2c1=O
Show InChI InChI=1S/C16H18O3/c17-13-10-19-14-8-4-7-12(15(14)16(13)18)9-11-5-2-1-3-6-11/h4,7-8,10-11,17H,1-3,5-6,9H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50277104
PNG
(CHEMBL4171016)
Show SMILES CC(C)CCc1cccc2occ(O)c(=O)c12
Show InChI InChI=1S/C14H16O3/c1-9(2)6-7-10-4-3-5-12-13(10)14(16)11(15)8-17-12/h3-5,8-9,15H,6-7H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50277107
PNG
(CHEMBL4173448)
Show SMILES OCCOc1coc2cccc(CC3CCCCC3)c2c1=O
Show InChI InChI=1S/C18H22O4/c19-9-10-21-16-12-22-15-8-4-7-14(17(15)18(16)20)11-13-5-2-1-3-6-13/h4,7-8,12-13,19H,1-3,5-6,9-11H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50277119
PNG
(CHEMBL4169568)
Show SMILES CC(C)CCc1ccc2occ(O)c(=O)c2c1
Show InChI InChI=1S/C14H16O3/c1-9(2)3-4-10-5-6-13-11(7-10)14(16)12(15)8-17-13/h5-9,15H,3-4H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50277127
PNG
(CHEMBL4176740)
Show SMILES CC(C)CCc1cccc2occ(OCCO)c(=O)c12
Show InChI InChI=1S/C16H20O4/c1-11(2)6-7-12-4-3-5-13-15(12)16(18)14(10-20-13)19-9-8-17/h3-5,10-11,17H,6-9H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50277102
PNG
(CHEMBL4163101)
Show SMILES Oc1coc2ccc(CC3CCCCC3)cc2c1=O
Show InChI InChI=1S/C16H18O3/c17-14-10-19-15-7-6-12(9-13(15)16(14)18)8-11-4-2-1-3-5-11/h6-7,9-11,17H,1-5,8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.90E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50403567
PNG
(CHEMBL4162825)
Show SMILES Oc1cccc2C\C(=C/c3ccccc3)C(=O)c12
Show InChI InChI=1S/C24H20F2N2O4S/c25-18-3-1-16(2-4-18)13-17-15-28(12-11-24(29)30)23-10-7-20(14-22(17)23)27-33(31,32)21-8-5-19(26)6-9-21/h1-10,14-15,27H,11-13H2,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 in mouse Y16 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay

Eur J Med Chem 152: 65-75 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.030
BindingDB Entry DOI: 10.7270/Q279477F
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50403561
PNG
(CHEMBL4173967)
Show SMILES COc1ccc(\C=C2/Cc3cccc(O)c3C2=O)cc1
Show InChI InChI=1S/C24H39N3O4/c1-24(2,3)31-23(29)26-13-8-12-22(28)25-14-9-17-30-21-11-7-10-20(18-21)19-27-15-5-4-6-16-27/h7,10-11,18H,4-6,8-9,12-17,19H2,1-3H3,(H,25,28)(H,26,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 in mouse Y16 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay

Eur J Med Chem 152: 65-75 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.030
BindingDB Entry DOI: 10.7270/Q279477F
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50403560
PNG
(CHEMBL4159681)
Show SMILES Oc1ccc(\C=C2/Cc3cccc(O)c3C2=O)cc1
Show InChI InChI=1S/C17H29N5O3S2/c1-17(2,3)25-16(24)21-6-4-5-14(23)20-7-8-26-10-12-11-27-15(22-12)9-13(18)19/h11H,4-10H2,1-3H3,(H3,18,19)(H,20,23)(H,21,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 in mouse Y16 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay

Eur J Med Chem 152: 65-75 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.030
BindingDB Entry DOI: 10.7270/Q279477F
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50277128
PNG
(CHEMBL4162662)
Show SMILES OCCCOc1coc2ccc(CC3CCCCC3)cc2c1=O
Show InChI InChI=1S/C19H24O4/c20-9-4-10-22-18-13-23-17-8-7-15(12-16(17)19(18)21)11-14-5-2-1-3-6-14/h7-8,12-14,20H,1-6,9-11H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50403569
PNG
(CHEMBL4159464)
Show SMILES Oc1ccc(CC2Cc3cccc(O)c3C2=O)cc1
Show InChI InChI=1S/C25H23FN2O4S/c1-17-2-9-22(10-3-17)33(31,32)27-21-8-11-24-23(15-21)19(16-28(24)13-12-25(29)30)14-18-4-6-20(26)7-5-18/h2-11,15-16,27H,12-14H2,1H3,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 in mouse Y16 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay

Eur J Med Chem 152: 65-75 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.030
BindingDB Entry DOI: 10.7270/Q279477F
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50424147
PNG
(CHEMBL2316359)
Show SMILES COc1cccc2occ(\C=C\C(=O)c3ccc(O)cc3)c(=O)c12
Show InChI InChI=1S/C19H14O5/c1-23-16-3-2-4-17-18(16)19(22)13(11-24-17)7-10-15(21)12-5-8-14(20)9-6-12/h2-11,20H,1H3/b10-7+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 in mouse pro-B Y16 cells after 48 hrs by WST1 assay

Eur J Med Chem 59: 31-8 (2013)


Article DOI: 10.1016/j.ejmech.2012.11.007
BindingDB Entry DOI: 10.7270/Q2PV6MP4
More data for this
Ligand-Target Pair
Interleukin-5


(Mus musculus)		BDBM50277094
PNG
(CHEMBL4173374)
Show SMILES CC(C)CCc1ccc2occ(OCCCO)c(=O)c2c1
Show InChI InChI=1S/C17H22O4/c1-12(2)4-5-13-6-7-15-14(10-13)17(19)16(11-21-15)20-9-3-8-18/h6-7,10-12,18H,3-5,8-9H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair