Compile Data Set for Download or QSAR

Found 90 hits with Last Name = 'horváth' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323373 (1,2-dicyclohexyl-3-(pyridin-3-yl)propan-1-one O-3-...) Show SMILES Clc1cccc(NC(=O)O\N=C(\C(Cc2cccnc2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C27H34ClN3O2/c28-23-14-7-15-24(18-23)30-27(32)33-31-26(22-12-5-2-6-13-22)25(21-10-3-1-4-11-21)17-20-9-8-16-29-19-20/h7-9,14-16,18-19,21-22,25H,1-6,10-13,17H2,(H,30,32)/b31-26+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM86716 (CAS_63540-28-3 | CHEMBL239800 | Fenobam | NSC_2162...) Show SMILES Cn1cc(O)nc1NC(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-6,17H,1H3,(H2,13,14,15,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at human mGLUR1				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM86716 (CAS_63540-28-3 | CHEMBL239800 | Fenobam | NSC_2162...) Show SMILES Cn1cc(O)nc1NC(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-6,17H,1H3,(H2,13,14,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Binding affinity to human mGluR5				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323380 ((1,2-dicyclohexyl-3-(6-thioxocyclohexa-1,3-dienyl)...) Show SMILES Cc1cccc(NC(=O)O\N=C(\C(Cc2cccs2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C27H36N2O2S/c1-20-10-8-15-23(18-20)28-27(30)31-29-26(22-13-6-3-7-14-22)25(19-24-16-9-17-32-24)21-11-4-2-5-12-21/h8-10,15-18,21-22,25H,2-7,11-14,19H2,1H3,(H,28,30)/b29-26+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323371 ((+)-1,2-dicyclohexyl-3-(1H-imidazol-1-yl)propan-1-...) Show SMILES Clc1cccc(NC(=O)O\N=C(\C(Cn2ccnc2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C25H33ClN4O2/c26-21-12-7-13-22(16-21)28-25(31)32-29-24(20-10-5-2-6-11-20)23(17-30-15-14-27-18-30)19-8-3-1-4-9-19/h7,12-16,18-20,23H,1-6,8-11,17H2,(H,28,31)/b29-24+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323378 ((3-chlorophenylamino)(1,2-dicyclohexyl-3-(6-thioxo...) Show SMILES Clc1cccc(NC(=O)O\N=C(\C(Cc2cccs2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C26H33ClN2O2S/c27-21-13-7-14-22(17-21)28-26(30)31-29-25(20-11-5-2-6-12-20)24(18-23-15-8-16-32-23)19-9-3-1-4-10-19/h7-8,13-17,19-20,24H,1-6,9-12,18H2,(H,28,30)/b29-25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323379 ((1,2-dicyclohexyl-3-(6-thioxocyclohexa-1,3-dienyl)...) Show SMILES Fc1cccc(NC(=O)O\N=C(\C(Cc2cccs2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C26H33FN2O2S/c27-21-13-7-14-22(17-21)28-26(30)31-29-25(20-11-5-2-6-12-20)24(18-23-15-8-16-32-23)19-9-3-1-4-10-19/h7-8,13-17,19-20,24H,1-6,9-12,18H2,(H,28,30)/b29-25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323377 ((3-chlorophenylamino)(1,2-dicyclohexyl-3-(5-thioxo...) Show SMILES Clc1cccc(NC(=O)O\N=C(\C(Cc2ccsc2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C26H33ClN2O2S/c27-22-12-7-13-23(17-22)28-26(30)31-29-25(21-10-5-2-6-11-21)24(16-19-14-15-32-18-19)20-8-3-1-4-9-20/h7,12-15,17-18,20-21,24H,1-6,8-11,16H2,(H,28,30)/b29-25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323375 (CHEMBL1209400 | c1,2-dicyclohexyl-3-(1H-pyrrol-3-y...) Show SMILES Clc1cccc(NC(=O)O\N=C(\C(Cc2cc[nH]c2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C26H34ClN3O2/c27-22-12-7-13-23(17-22)29-26(31)32-30-25(21-10-5-2-6-11-21)24(16-19-14-15-28-18-19)20-8-3-1-4-9-20/h7,12-15,17-18,20-21,24,28H,1-6,8-11,16H2,(H,29,31)/b30-25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323365 (1,2-dicyclohexyl-3-phenylpropan-1-one O-3-chloroph...) Show SMILES Clc1cccc(NC(=O)O\N=C(\C(Cc2ccccc2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C28H35ClN2O2/c29-24-17-10-18-25(20-24)30-28(32)33-31-27(23-15-8-3-9-16-23)26(22-13-6-2-7-14-22)19-21-11-4-1-5-12-21/h1,4-5,10-12,17-18,20,22-23,26H,2-3,6-9,13-16,19H2,(H,30,32)/b31-27+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323363 (1,2-dicyclohexyl-3-phenylpropan-1-one O-m-tolylcar...) Show SMILES Cc1cccc(NC(=O)O\N=C(\C(Cc2ccccc2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C29H38N2O2/c1-22-12-11-19-26(20-22)30-29(32)33-31-28(25-17-9-4-10-18-25)27(24-15-7-3-8-16-24)21-23-13-5-2-6-14-23/h2,5-6,11-14,19-20,24-25,27H,3-4,7-10,15-18,21H2,1H3,(H,30,32)/b31-28+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323370 (1,2-dicyclohexyl-3-(1H-imidazol-1-yl)propan-1-one ...) Show SMILES Fc1cccc(NC(=O)O\N=C(\C(Cn2ccnc2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C25H33FN4O2/c26-21-12-7-13-22(16-21)28-25(31)32-29-24(20-10-5-2-6-11-20)23(17-30-15-14-27-18-30)19-8-3-1-4-9-19/h7,12-16,18-20,23H,1-6,8-11,17H2,(H,28,31)/b29-24+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50084137 (2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...) Show SMILES Cc1cccc(n1)C#Cc1ccccc1 Show InChI InChI=1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at human mGLUR1				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50084137 (2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...) Show SMILES Cc1cccc(n1)C#Cc1ccccc1 Show InChI InChI=1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	36.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Binding affinity to human mGluR5				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323369 (3-((1,2-dicyclohexyl-3-(1H-imidazol-1-yl)propylide...) Show SMILES O=C(Nc1cccc(c1)C#N)O\N=C(\C(Cn1ccnc1)C1CCCCC1)C1CCCCC1 Show InChI InChI=1S/C26H33N5O2/c27-17-20-8-7-13-23(16-20)29-26(32)33-30-25(22-11-5-2-6-12-22)24(18-31-15-14-28-19-31)21-9-3-1-4-10-21/h7-8,13-16,19,21-22,24H,1-6,9-12,18H2,(H,29,32)/b30-25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323374 (1,2-dicyclohexyl-3-(pyridin-2-yl)propan-1-one O-3-...) Show SMILES Clc1cccc(NC(=O)O\N=C(\C(Cc2ccccn2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C27H34ClN3O2/c28-22-14-9-16-24(18-22)30-27(32)33-31-26(21-12-5-2-6-13-21)25(20-10-3-1-4-11-20)19-23-15-7-8-17-29-23/h7-9,14-18,20-21,25H,1-6,10-13,19H2,(H,30,32)/b31-26+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323366 (1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-...) Show SMILES Fc1cccc(CC(C2CCCCC2)C(=N\OC(=O)Nc2cccc(Cl)c2)\C2CCCCC2)c1 Show InChI InChI=1S/C28H34ClFN2O2/c29-23-14-8-16-25(19-23)31-28(33)34-32-27(22-12-5-2-6-13-22)26(21-10-3-1-4-11-21)18-20-9-7-15-24(30)17-20/h7-9,14-17,19,21-22,26H,1-6,10-13,18H2,(H,31,33)/b32-27+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323372 (1,2-dicyclohexyl-3-(4-methyl-1H-imidazol-1-yl)prop...) Show SMILES Cc1cn(CC(C2CCCCC2)C(=N\OC(=O)Nc2cccc(Cl)c2)\C2CCCCC2)cn1 Show InChI InChI=1S/C26H35ClN4O2/c1-19-16-31(18-28-19)17-24(20-9-4-2-5-10-20)25(21-11-6-3-7-12-21)30-33-26(32)29-23-14-8-13-22(27)15-23/h8,13-16,18,20-21,24H,2-7,9-12,17H2,1H3,(H,29,32)/b30-25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416269 (CHEMBL1082329) Show SMILES Clc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)c1ccc(Br)o1 Show InChI InChI=1S/C17H15BrClN5O2/c18-15-8-7-14(26-15)17(25)23-9-2-1-6-13(23)16-20-22-24(21-16)12-5-3-4-11(19)10-12/h3-5,7-8,10,13H,1-2,6,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323364 (1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-...) Show SMILES Cc1cccc(NC(=O)O\N=C(\C(Cc2cccc(F)c2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C29H37FN2O2/c1-21-10-8-17-26(18-21)31-29(33)34-32-28(24-14-6-3-7-15-24)27(23-12-4-2-5-13-23)20-22-11-9-16-25(30)19-22/h8-11,16-19,23-24,27H,2-7,12-15,20H2,1H3,(H,31,33)/b32-28+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416264 (CHEMBL1082987) Show SMILES Clc1cccc(c1)-n1nnc(n1)[C@H]1CCCCN1C(=O)C1CCC1 |r| Show InChI InChI=1S/C17H20ClN5O/c18-13-7-4-8-14(11-13)23-20-16(19-21-23)15-9-1-2-10-22(15)17(24)12-5-3-6-12/h4,7-8,11-12,15H,1-3,5-6,9-10H2/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416276 (CHEMBL1082975) Show SMILES Cc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)C1CCC1 Show InChI InChI=1S/C18H23N5O/c1-13-6-4-9-15(12-13)23-20-17(19-21-23)16-10-2-3-11-22(16)18(24)14-7-5-8-14/h4,6,9,12,14,16H,2-3,5,7-8,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416263 (CHEMBL1086591) Show SMILES Clc1cccc(c1)-n1nnc(n1)[C@@H]1CCCCN1C(=O)C1CCC1 |r| Show InChI InChI=1S/C17H20ClN5O/c18-13-7-4-8-14(11-13)23-20-16(19-21-23)15-9-1-2-10-22(15)17(24)12-5-3-6-12/h4,7-8,11-12,15H,1-3,5-6,9-10H2/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323368 (1,2-dicyclohexyl-3-(1H-imidazol-1-yl)propan-1-one ...) Show SMILES FC(F)(F)c1cccc(NC(=O)O\N=C(\C(Cn2ccnc2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C26H33F3N4O2/c27-26(28,29)21-12-7-13-22(16-21)31-25(34)35-32-24(20-10-5-2-6-11-20)23(17-33-15-14-30-18-33)19-8-3-1-4-9-19/h7,12-16,18-20,23H,1-6,8-11,17H2,(H,31,34)/b32-24+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416265 (CHEMBL1083340) Show SMILES Cc1ccc(s1)C(=O)N1CSCC1c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C17H14ClN3O2S2/c1-10-5-6-14(25-10)17(22)21-9-24-8-13(21)16-19-15(20-23-16)11-3-2-4-12(18)7-11/h2-7,13H,8-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	83.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416270 (CHEMBL1082976) Show SMILES Clc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)C1CCCC1 Show InChI InChI=1S/C18H22ClN5O/c19-14-8-5-9-15(12-14)24-21-17(20-22-24)16-10-3-4-11-23(16)18(25)13-6-1-2-7-13/h5,8-9,12-13,16H,1-4,6-7,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323381 ((1,2-dicyclohexyl-3-(6-thioxocyclohexa-1,3-dienyl)...) Show SMILES COc1cccc(NC(=O)O\N=C(\C(Cc2cccs2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C27H36N2O3S/c1-31-23-15-8-14-22(18-23)28-27(30)32-29-26(21-12-6-3-7-13-21)25(19-24-16-9-17-33-24)20-10-4-2-5-11-20/h8-9,14-18,20-21,25H,2-7,10-13,19H2,1H3,(H,28,30)/b29-26+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416260 (CHEMBL1083598) Show SMILES Cc1ccc(s1)C(=O)N1CCCC1c1nnn(n1)-c1cccc(Cl)c1 Show InChI InChI=1S/C17H16ClN5OS/c1-11-7-8-15(25-11)17(24)22-9-3-6-14(22)16-19-21-23(20-16)13-5-2-4-12(18)10-13/h2,4-5,7-8,10,14H,3,6,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	89.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416271 (CHEMBL1084474) Show SMILES Cc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)C1CCCC1 Show InChI InChI=1S/C19H25N5O/c1-14-7-6-10-16(13-14)24-21-18(20-22-24)17-11-4-5-12-23(17)19(25)15-8-2-3-9-15/h6-7,10,13,15,17H,2-5,8-9,11-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323382 ((E)-2-((1H-imidazol-1-yl)methyl)cyclohexanone O-ph...) Show SMILES O=C(Nc1ccccc1)O\N=C1/CCCCC1Cn1ccnc1 Show InChI InChI=1S/C17H20N4O2/c22-17(19-15-7-2-1-3-8-15)23-20-16-9-5-4-6-14(16)12-21-11-10-18-13-21/h1-3,7-8,10-11,13-14H,4-6,9,12H2,(H,19,22)/b20-16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416272 (CHEMBL1084475) Show SMILES Cc1ccc(o1)C(=O)N1CCCC1c1nnn(n1)-c1cccc(Cl)c1 Show InChI InChI=1S/C17H16ClN5O2/c1-11-7-8-15(25-11)17(24)22-9-3-6-14(22)16-19-21-23(20-16)13-5-2-4-12(18)10-13/h2,4-5,7-8,10,14H,3,6,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323387 (1,2-dicyclohexyl-3-(pyridin-4-yl)propan-1-one O-3-...) Show SMILES Clc1cccc(NC(=O)O\N=C(\C(Cc2ccncc2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C27H34ClN3O2/c28-23-12-7-13-24(19-23)30-27(32)33-31-26(22-10-5-2-6-11-22)25(21-8-3-1-4-9-21)18-20-14-16-29-17-15-20/h7,12-17,19,21-22,25H,1-6,8-11,18H2,(H,30,32)/b31-26+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416275 (CHEMBL1083341) Show SMILES Cc1ccc(s1)C(=O)N1CCCC1c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H16ClN3O2S/c1-11-7-8-15(25-11)18(23)22-9-3-6-14(22)17-20-16(21-24-17)12-4-2-5-13(19)10-12/h2,4-5,7-8,10,14H,3,6,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416279 (CHEMBL1084476) Show SMILES Clc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)c1ccco1 Show InChI InChI=1S/C17H16ClN5O2/c18-12-5-3-6-13(11-12)23-20-16(19-21-23)14-7-1-2-9-22(14)17(24)15-8-4-10-25-15/h3-6,8,10-11,14H,1-2,7,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50342430 ((R)-cyclobutyl(2-(3-m-tolyl-1,2,4-oxadiazol-5-yl)p...) Show SMILES Cc1cccc(c1)-c1noc(n1)[C@H]1CCCCN1C(=O)C1CCC1 |r| Show InChI InChI=1S/C19H23N3O2/c1-13-6-4-9-15(12-13)17-20-18(24-21-17)16-10-2-3-11-22(16)19(23)14-7-5-8-14/h4,6,9,12,14,16H,2-3,5,7-8,10-11H2,1H3/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416273 (CHEMBL1084477) Show SMILES CC(C)C(=O)N1CCCCC1c1nnn(n1)-c1cccc(Cl)c1 Show InChI InChI=1S/C16H20ClN5O/c1-11(2)16(23)21-9-4-3-8-14(21)15-18-20-22(19-15)13-7-5-6-12(17)10-13/h5-7,10-11,14H,3-4,8-9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416266 (CHEMBL1082722) Show SMILES Cc1ccc(s1)C(=O)N1CCCC1c1nc(no1)-c1cccc(C)c1 Show InChI InChI=1S/C19H19N3O2S/c1-12-5-3-6-14(11-12)17-20-18(24-21-17)15-7-4-10-22(15)19(23)16-9-8-13(2)25-16/h3,5-6,8-9,11,15H,4,7,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50026040 (CHEMBL2093131) Show SMILES O=C(Nc1ccccc1)ON=C1CCCCC1Cn1ccnc1 Show InChI InChI=1S/C17H20N4O2/c22-17(19-15-7-2-1-3-8-15)23-20-16-9-5-4-6-14(16)12-21-11-10-18-13-21/h1-3,7-8,10-11,13-14H,4-6,9,12H2,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50342460 ((S)-cyclobutyl(2-(3-(3-methoxyphenyl)-1,2,4-oxadia...) Show SMILES COc1cccc(c1)-c1noc(n1)[C@@H]1CCCCN1C(=O)C1CCC1 |r| Show InChI InChI=1S/C19H23N3O3/c1-24-15-9-5-8-14(12-15)17-20-18(25-21-17)16-10-2-3-11-22(16)19(23)13-6-4-7-13/h5,8-9,12-13,16H,2-4,6-7,10-11H2,1H3/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416277 (CHEMBL1082635) Show SMILES COCC(=O)N1CCCC1c1nc(no1)-c1cccc(C)c1 Show InChI InChI=1S/C16H19N3O3/c1-11-5-3-6-12(9-11)15-17-16(22-18-15)13-7-4-8-19(13)14(20)10-21-2/h3,5-6,9,13H,4,7-8,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416268 (CHEMBL1082637) Show SMILES Clc1cccc(c1)-c1noc(n1)C1CCCN1C(=O)c1cccs1 Show InChI InChI=1S/C17H14ClN3O2S/c18-12-5-1-4-11(10-12)15-19-16(23-20-15)13-6-2-8-21(13)17(22)14-7-3-9-24-14/h1,3-5,7,9-10,13H,2,6,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416267 (CHEMBL1082636) Show SMILES Clc1cccc(c1)-c1noc(n1)C1CSCN1C(=O)c1ccco1 Show InChI InChI=1S/C16H12ClN3O3S/c17-11-4-1-3-10(7-11)14-18-15(23-19-14)12-8-24-9-20(12)16(21)13-5-2-6-22-13/h1-7,12H,8-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416278 (CHEMBL1082328) Show SMILES O=C(N1CCCCC1c1nc(no1)-c1cccc(c1)C#N)c1cccs1 Show InChI InChI=1S/C19H16N4O2S/c20-12-13-5-3-6-14(11-13)17-21-18(25-22-17)15-7-1-2-9-23(15)19(24)16-8-4-10-26-16/h3-6,8,10-11,15H,1-2,7,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50342457 ((S)-(2-(3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl)pi...) Show SMILES Clc1cccc(c1)-c1noc(n1)[C@@H]1CCCCN1C(=O)C1CCC1 |r| Show InChI InChI=1S/C18H20ClN3O2/c19-14-8-4-7-13(11-14)16-20-17(24-21-16)15-9-1-2-10-22(15)18(23)12-5-3-6-12/h4,7-8,11-12,15H,1-3,5-6,9-10H2/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	204	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Binding affinity to human mGluR5				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416274 (CHEMBL1082666) Show SMILES O=C(C1CCC1)N1CCCCC1c1nnn(n1)-c1cccc(c1)C#N Show InChI InChI=1S/C18H20N6O/c19-12-13-5-3-8-15(11-13)24-21-17(20-22-24)16-9-1-2-10-23(16)18(25)14-6-4-7-14/h3,5,8,11,14,16H,1-2,4,6-7,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	229	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416261 (CHEMBL1082667) Show SMILES Clc1cccc(c1)-n1nnc(n1)C1CCCN(C1)C(=O)c1cccs1 Show InChI InChI=1S/C17H16ClN5OS/c18-13-5-1-6-14(10-13)23-20-16(19-21-23)12-4-2-8-22(11-12)17(24)15-7-3-9-25-15/h1,3,5-7,9-10,12H,2,4,8,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323376 (1,2-dicyclohexyl-3-(furan-2-yl)propan-1-one O-3-ch...) Show SMILES Clc1cccc(NC(=O)O\N=C(\C(Cc2ccco2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C26H33ClN2O3/c27-21-13-7-14-22(17-21)28-26(30)32-29-25(20-11-5-2-6-12-20)24(18-23-15-8-16-31-23)19-9-3-1-4-10-19/h7-8,13-17,19-20,24H,1-6,9-12,18H2,(H,28,30)/b29-25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	438	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416262 (CHEMBL1082668) Show SMILES Fc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)c1ccc(Br)o1 Show InChI InChI=1S/C17H15BrFN5O2/c18-15-8-7-14(26-15)17(25)23-9-2-1-6-13(23)16-20-22-24(21-16)12-5-3-4-11(19)10-12/h3-5,7-8,10,13H,1-2,6,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	457	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416263 (CHEMBL1086591) Show SMILES Clc1cccc(c1)-n1nnc(n1)[C@@H]1CCCCN1C(=O)C1CCC1 |r| Show InChI InChI=1S/C17H20ClN5O/c18-13-7-4-8-14(11-13)23-20-16(19-21-23)15-9-1-2-10-22(15)17(24)12-5-3-6-12/h4,7-8,11-12,15H,1-3,5-6,9-10H2/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	741	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323367 (1,2-dicyclohexyl-3-(4-(dimethylamino)phenyl)propan...) Show SMILES CN(C)c1ccc(CC(C2CCCCC2)C(=N\OC(=O)Nc2cccc(Cl)c2)\C2CCCCC2)cc1 Show InChI InChI=1S/C30H40ClN3O2/c1-34(2)27-18-16-22(17-19-27)20-28(23-10-5-3-6-11-23)29(24-12-7-4-8-13-24)33-36-30(35)32-26-15-9-14-25(31)21-26/h9,14-19,21,23-24,28H,3-8,10-13,20H2,1-2H3,(H,32,35)/b33-29+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 90 total )  |  Next  |  Last  >>

Jump to: