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Compile Data Set for Download or QSAR

Found 2 hits with Last Name = 'vallone' and Initial = 'a'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-dependent L-type calcium channel subunit alpha-1C


(RAT)
BDBM50462274
PNG
(CHEMBL4246869)
Show SMILES Clc1ccc(-c2ccc(CNCC3CCNCC3)o2)c(c1)-c1ccccc1
Show InChI InChI=1S/C23H25ClN2O/c24-19-6-8-21(22(14-19)18-4-2-1-3-5-18)23-9-7-20(27-23)16-26-15-17-10-12-25-13-11-17/h1-9,14,17,25-26H,10-13,15-16H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.30E+3n/an/an/an/an/an/a



University of Siena

Curated by ChEMBL


Assay Description
Inhibition of CaV1.2 channel in rat tail artery myocytes assessed as reduction in Ba2+ current at -50 mV holding potential by whole-cell patch-clamp ...


Eur J Med Chem 150: 698-718 (2018)


Article DOI: 10.1016/j.ejmech.2018.03.024
BindingDB Entry DOI: 10.7270/Q2PC3518
More data for this
Ligand-Target Pair
Phosphoethanolamine N-methyltransferase


(Plasmodium falciparum)
BDBM50462274
PNG
(CHEMBL4246869)
Show SMILES Clc1ccc(-c2ccc(CNCC3CCNCC3)o2)c(c1)-c1ccccc1
Show InChI InChI=1S/C23H25ClN2O/c24-19-6-8-21(22(14-19)18-4-2-1-3-5-18)23-9-7-20(27-23)16-26-15-17-10-12-25-13-11-17/h1-9,14,17,25-26H,10-13,15-16H2
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.43E+4n/an/an/an/an/an/a



University of Siena

Curated by ChEMBL


Assay Description
Inhibition of plasmodium falciparum phosphoethanolamine N-methyltransferase expressed in Escherichia coli using phosphoethanolamine as substrate and ...


Eur J Med Chem 150: 698-718 (2018)


Article DOI: 10.1016/j.ejmech.2018.03.024
BindingDB Entry DOI: 10.7270/Q2PC3518
More data for this
Ligand-Target Pair