Found 36 hits with Last Name = 'taggart' and Initial = 'akp' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50613996
(CHEMBL5281961)Show SMILES COc1cc(Cl)c(c(Cl)c1)-n1c(C)cc(=O)c2c(F)cncc12 |(-.67,5.77,;.66,5,;.66,3.46,;-.67,2.69,;-.67,1.16,;-2.01,.39,;.66,.39,;2,1.16,;3.33,.39,;1.99,2.7,;.66,-1.15,;2,-1.92,;3.33,-1.15,;2,-3.46,;.66,-4.23,;.66,-5.77,;-.67,-3.46,;-2,-4.23,;-2,-5.77,;-3.33,-3.47,;-3.33,-1.92,;-2,-1.15,;-.67,-1.92,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM585727
(8-chloro-1-(2,6-dichlorophenyl)-5- (2-hydroxyethox...)Show SMILES Cc1cc(=O)c2c(OCCO)ncc(Cl)c2n1-c1c(Cl)cccc1Cl |(4,1.07,;2.67,.3,;2.67,-1.24,;1.33,-2.01,;1.33,-3.55,;,-1.24,;-1.33,-2.01,;-1.33,-3.55,;-2.67,-4.32,;-2.67,-5.86,;-4,-6.63,;-2.67,-1.24,;-2.67,.3,;-1.33,1.07,;-1.33,2.61,;,.3,;1.33,1.07,;1.33,3.55,;2.67,4.32,;4,3.55,;2.67,5.86,;1.33,6.63,;,5.86,;,4.32,;-1.33,3.55,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50613997
(CHEMBL5280047)Show SMILES Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(OCC(O)CO)cc1Cl |(3.33,-3.08,;2,-3.85,;2,-5.39,;.66,-6.16,;.66,-7.7,;-.67,-5.39,;-2,-6.16,;-2,-7.7,;-3.33,-5.4,;-3.33,-3.85,;-2,-3.08,;-.67,-3.85,;.66,-3.08,;.66,-1.54,;-.67,-.77,;-2.01,-1.54,;-.67,.77,;.66,1.54,;.66,3.08,;-.67,3.85,;-.67,5.39,;.66,6.16,;-2,6.16,;-2,7.7,;1.99,.77,;2,-.76,;3.33,-1.53,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM585709
(8-chloro-1-(2,6-dichlorophenyl)-5- (2-(2-(2-(2- hy...)Show SMILES Cc1cc(=O)c2c(OCCOCCOCCOCCO)ncc(Cl)c2n1-c1c(Cl)cccc1Cl |(12.06,-4.58,;10.73,-3.81,;9.39,-4.58,;8.06,-3.81,;6.73,-4.58,;8.06,-2.27,;6.73,-1.5,;5.39,-2.27,;4.06,-1.5,;2.72,-2.27,;1.39,-1.5,;.06,-2.27,;-1.28,-1.5,;-2.61,-2.27,;-3.94,-1.5,;-5.28,-2.27,;-6.61,-1.5,;-7.94,-2.27,;-9.28,-1.5,;-10.61,-2.27,;6.73,.04,;8.06,.81,;9.39,.04,;10.73,.81,;9.39,-1.5,;10.73,-2.27,;12.06,-1.5,;13.39,-2.27,;13.39,-3.81,;14.73,-1.5,;14.73,.04,;13.39,.81,;12.06,.04,;11.43,1.45,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50613999
(CHEMBL5289977)Show SMILES COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |(-1.33,-5,;-2.66,-4.23,;-2.66,-2.69,;-4,-1.93,;-4,-.38,;-2.67,.39,;-1.89,1.72,;-1.34,-.38,;-0,.39,;1.33,-.38,;2.66,.39,;4,-.38,;1.33,-1.92,;-0,-2.69,;-0,-4.23,;-1.34,-1.92,;-0,1.93,;-1.34,2.7,;-2.67,1.93,;-1.33,4.23,;-0,5,;1.33,4.24,;1.34,2.7,;2.67,1.93,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50613992
(CHEMBL5282689)Show SMILES CSc1c(C#N)c(=O)c2ccc(F)cc2n1-c1c(Cl)cccc1Cl |(4.67,-.77,;3.33,0,;2,-.77,;2,-2.31,;3.33,-3.08,;4.67,-3.85,;.66,-3.08,;.66,-4.62,;-.67,-2.31,;-1.99,-3.08,;-3.33,-2.31,;-3.33,-.77,;-4.67,0,;-2,0,;-.67,-.77,;.66,0,;.66,1.54,;-.67,2.31,;-2,1.54,;-.67,3.85,;.67,4.62,;2,3.85,;2,2.32,;3.34,1.55,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM585682
(8-chloro-1-(2,6-dichlorophenyl)-5- (2,3-dihydroxyp...)Show SMILES OCC(O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |(-3.78,-7.53,;-4.55,-6.2,;-3.46,-5.11,;-2.12,-5.88,;-3.46,-3.57,;-2.12,-2.8,;-2.12,-1.26,;-3.46,-.49,;-3.46,1.05,;-2.12,1.82,;-2.12,3.36,;-.79,1.05,;.54,1.82,;1.88,1.05,;3.21,1.82,;4.55,1.05,;1.88,-.49,;.54,-1.26,;.54,-2.8,;-.79,-.49,;.54,4.45,;-.79,5.22,;-2.12,4.45,;-.79,6.76,;.54,7.53,;1.88,6.76,;1.88,5.22,;3.21,4.45,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50614001
(CHEMBL5278366)Show SMILES Cc1cc(=O)c2c(OCC(O)CC(O)CO)ncc(Cl)c2n1-c1c(Cl)cccc1Cl |(3.33,3.47,;2,2.7,;2,1.16,;.66,.39,;.66,-1.15,;-.67,1.16,;-2,.39,;-2,-1.15,;-.66,-1.92,;-.66,-3.46,;-2,-4.23,;.67,-4.23,;.67,-5.77,;-.66,-6.54,;2,-6.54,;2,-8.08,;-3.33,1.15,;-3.33,2.7,;-2,3.47,;-1.23,4.8,;-.67,2.7,;.66,3.47,;.66,5.01,;-.67,5.78,;-2.01,5.01,;-.67,7.31,;.66,8.08,;1.99,7.32,;2,5.78,;3.33,5.01,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM585681
((R)-8-chloro-1-(2,6- dichlorophenyl)-5-(2,3- dihyd...)Show SMILES OC[C@@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wD:2.2,(-3.78,-7.53,;-4.55,-6.2,;-3.46,-5.11,;-2.12,-5.88,;-3.46,-3.57,;-2.12,-2.8,;-2.12,-1.26,;-3.46,-.49,;-3.46,1.05,;-2.12,1.82,;-2.12,3.36,;-.79,1.05,;.54,1.82,;1.88,1.05,;3.21,1.82,;4.55,1.05,;1.88,-.49,;.54,-1.26,;.54,-2.8,;-.79,-.49,;.54,4.45,;-.79,5.22,;-2.12,4.45,;-.79,6.76,;.54,7.53,;1.88,6.76,;1.88,5.22,;3.21,4.45,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM585681
((R)-8-chloro-1-(2,6- dichlorophenyl)-5-(2,3- dihyd...)Show SMILES OC[C@@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wD:2.2,(-3.78,-7.53,;-4.55,-6.2,;-3.46,-5.11,;-2.12,-5.88,;-3.46,-3.57,;-2.12,-2.8,;-2.12,-1.26,;-3.46,-.49,;-3.46,1.05,;-2.12,1.82,;-2.12,3.36,;-.79,1.05,;.54,1.82,;1.88,1.05,;3.21,1.82,;4.55,1.05,;1.88,-.49,;.54,-1.26,;.54,-2.8,;-.79,-.49,;.54,4.45,;-.79,5.22,;-2.12,4.45,;-.79,6.76,;.54,7.53,;1.88,6.76,;1.88,5.22,;3.21,4.45,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50614002
(CHEMBL5285569)Show SMILES CS(=O)(=O)CCCOc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |(-6.66,-5,;-5.33,-4.23,;-4.56,-2.9,;-6.1,-2.9,;-4,-5,;-2.66,-4.23,;-1.33,-5,;0,-4.23,;0,-2.69,;-1.33,-1.93,;-1.33,-.38,;0,.38,;.77,1.72,;1.33,-.38,;2.66,.39,;4,-.38,;5.33,.39,;6.66,-.38,;4,-1.92,;2.66,-2.69,;2.66,-4.23,;1.33,-1.92,;2.66,1.93,;4,2.7,;5.34,1.93,;3.99,4.24,;2.66,5,;1.33,4.23,;1.33,2.7,;-0,1.93,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50613994
(CHEMBL5269440)Show SMILES Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(cc1Cl)C#CCO |(3.33,-2.69,;2,-3.46,;2,-5,;.66,-5.77,;.66,-7.31,;-.67,-5,;-2,-5.77,;-2,-7.31,;-3.33,-5.01,;-3.33,-3.46,;-2,-2.69,;-.67,-3.46,;.66,-2.69,;.66,-1.15,;-.67,-.38,;-2.01,-1.15,;-.67,1.15,;.66,1.92,;1.99,1.16,;2,-.38,;3.33,-1.15,;.66,3.46,;.66,5,;.66,6.54,;-.67,7.31,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM585680
(US11530213, Example 1)Show SMILES OC[C@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wU:2.2,(-4.27,-7.27,;-4.67,-5.78,;-3.33,-5.01,;-2.25,-6.1,;-3.33,-3.47,;-2,-2.7,;-2,-1.16,;-3.33,-.39,;-3.33,1.15,;-2,1.92,;-2,3.46,;-.67,1.15,;.67,1.92,;2,1.15,;3.33,1.92,;4.67,1.15,;2,-.39,;.67,-1.16,;.67,-2.7,;-.67,-.39,;.67,4.19,;-.67,4.96,;-2,4.19,;-.67,6.5,;.67,7.27,;2,6.5,;2,4.96,;3.33,4.19,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM585699
(8-chloro-1-(2,6-dichlorophenyl)-5- (3-(2,3-dihydro...)Show SMILES Cc1cc(=O)c2c(OCC(O)COCC(O)CO)ncc(Cl)c2n1-c1c(Cl)cccc1Cl |(3.33,.95,;2,.18,;2,-1.36,;.67,-2.13,;.67,-3.67,;-.67,-1.36,;-2,-2.13,;-2,-3.67,;-3.33,-4.44,;-3.33,-5.98,;-4.67,-6.75,;-2,-6.75,;-.67,-5.98,;.67,-6.75,;2,-5.98,;2,-4.44,;3.33,-6.75,;4.67,-5.98,;-3.33,-1.36,;-3.33,.18,;-2,.95,;-2,2.49,;-.67,.18,;.67,.95,;.67,3.67,;-.67,4.44,;-2,3.67,;-.67,5.98,;.67,6.75,;2,5.98,;2,4.44,;3.33,3.67,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50613993
(CHEMBL5286246)Show SMILES Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(cc1Cl)C#N |(3.33,-1.54,;2,-2.31,;2,-3.85,;.66,-4.62,;.66,-6.16,;-.67,-3.85,;-2,-4.62,;-2,-6.16,;-3.33,-3.86,;-3.33,-2.31,;-2,-1.54,;-.67,-2.31,;.66,-1.54,;.66,0,;-.67,.77,;-2.01,0,;-.67,2.31,;.66,3.08,;1.99,2.31,;2,.78,;3.33,.01,;.66,4.62,;.66,6.16,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50613993
(CHEMBL5286246)Show SMILES Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(cc1Cl)C#N |(3.33,-1.54,;2,-2.31,;2,-3.85,;.66,-4.62,;.66,-6.16,;-.67,-3.85,;-2,-4.62,;-2,-6.16,;-3.33,-3.86,;-3.33,-2.31,;-2,-1.54,;-.67,-2.31,;.66,-1.54,;.66,0,;-.67,.77,;-2.01,0,;-.67,2.31,;.66,3.08,;1.99,2.31,;2,.78,;3.33,.01,;.66,4.62,;.66,6.16,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50613995
(CHEMBL5290509)Show SMILES Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(cc1Cl)C#CCN1CCOCC1 |(3.33,-3.85,;2,-4.62,;2,-6.16,;.66,-6.93,;.66,-8.47,;-.67,-6.16,;-2,-6.93,;-2,-8.47,;-3.33,-6.16,;-3.33,-4.62,;-2,-3.85,;-.67,-4.62,;.66,-3.85,;.66,-2.31,;-.67,-1.54,;-2,-2.31,;-.67,-0,;.66,.77,;1.99,0,;2,-1.53,;3.34,-2.3,;.66,2.31,;.66,3.85,;.66,5.39,;-.67,6.16,;-2,5.39,;-3.34,6.16,;-3.34,7.7,;-2,8.47,;-.67,7.7,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM585688
(8-chloro-1-(2,6-dichlorophenyl)-5- ((1,3-dihydroxy...)Show SMILES OCC(CO)Oc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |(-5.33,-4.46,;-4,-3.69,;-2.67,-4.46,;-2.67,-6,;-4,-6.77,;-1.33,-3.69,;-1.33,-2.15,;-2.67,-1.38,;-2.67,.16,;-1.33,.93,;-1.33,2.47,;,.16,;1.33,.93,;2.67,.16,;4,.93,;5.33,.16,;2.67,-1.38,;1.33,-2.15,;1.33,-3.69,;,-1.38,;1.33,3.69,;,4.46,;-1.33,3.69,;,6,;1.33,6.77,;2.67,6,;2.67,4.46,;4,3.69,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50614000
(CHEMBL5286244)Show SMILES COc1ncc(C)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |(-1.33,-5,;-2.66,-4.23,;-2.66,-2.69,;-4,-1.93,;-4,-.38,;-2.66,.38,;-1.89,1.72,;-1.34,-.38,;-0,.39,;1.33,-.38,;2.66,.39,;4,-.38,;1.33,-1.92,;-0,-2.69,;-0,-4.23,;-1.34,-1.92,;-0,1.93,;-1.34,2.7,;-2.67,1.93,;-1.33,4.23,;-0,5,;1.33,4.24,;1.34,2.7,;2.67,1.93,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50613998
(CHEMBL5277008)Show SMILES Cc1cc(=O)c2c(OCC(O)CO)nc(cc2n1-c1c(Cl)cccc1Cl)N1CCOCC1 |(5.33,2.31,;4,1.54,;4,0,;2.66,-.77,;2.66,-2.31,;1.33,0,;0,-.77,;0,-2.31,;1.34,-3.08,;1.34,-4.62,;0,-5.39,;2.67,-5.39,;2.67,-6.93,;-1.33,-.01,;-1.33,1.54,;-0,2.31,;1.33,1.54,;2.66,2.31,;2.66,3.85,;1.33,4.62,;-.01,3.85,;1.33,6.16,;2.66,6.93,;3.99,6.16,;4,4.62,;5.34,3.85,;-2.67,2.31,;-4,1.54,;-5.34,2.31,;-5.34,3.85,;-4,4.62,;-2.67,3.85,)| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human)) | BDBM50613992
(CHEMBL5282689)Show SMILES CSc1c(C#N)c(=O)c2ccc(F)cc2n1-c1c(Cl)cccc1Cl |(4.67,-.77,;3.33,0,;2,-.77,;2,-2.31,;3.33,-3.08,;4.67,-3.85,;.66,-3.08,;.66,-4.62,;-.67,-2.31,;-1.99,-3.08,;-3.33,-2.31,;-3.33,-.77,;-4.67,0,;-2,0,;-.67,-.77,;.66,0,;.66,1.54,;-.67,2.31,;-2,1.54,;-.67,3.85,;.67,4.62,;2,3.85,;2,2.32,;3.34,1.55,)| | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 2.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50613993
(CHEMBL5286246)Show SMILES Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(cc1Cl)C#N |(3.33,-1.54,;2,-2.31,;2,-3.85,;.66,-4.62,;.66,-6.16,;-.67,-3.85,;-2,-4.62,;-2,-6.16,;-3.33,-3.86,;-3.33,-2.31,;-2,-1.54,;-.67,-2.31,;.66,-1.54,;.66,0,;-.67,.77,;-2.01,0,;-.67,2.31,;.66,3.08,;1.99,2.31,;2,.78,;3.33,.01,;.66,4.62,;.66,6.16,)| | PDB
MMDB
Reactome pathway
KEGG
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B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| PC cid
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UniChem
| | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
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| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50613992
(CHEMBL5282689)Show SMILES CSc1c(C#N)c(=O)c2ccc(F)cc2n1-c1c(Cl)cccc1Cl |(4.67,-.77,;3.33,0,;2,-.77,;2,-2.31,;3.33,-3.08,;4.67,-3.85,;.66,-3.08,;.66,-4.62,;-.67,-2.31,;-1.99,-3.08,;-3.33,-2.31,;-3.33,-.77,;-4.67,0,;-2,0,;-.67,-.77,;.66,0,;.66,1.54,;-.67,2.31,;-2,1.54,;-.67,3.85,;.67,4.62,;2,3.85,;2,2.32,;3.34,1.55,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
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UniChem
| | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily KQT member 1
(Homo sapiens (Human)) | BDBM50613992
(CHEMBL5282689)Show SMILES CSc1c(C#N)c(=O)c2ccc(F)cc2n1-c1c(Cl)cccc1Cl |(4.67,-.77,;3.33,0,;2,-.77,;2,-2.31,;3.33,-3.08,;4.67,-3.85,;.66,-3.08,;.66,-4.62,;-.67,-2.31,;-1.99,-3.08,;-3.33,-2.31,;-3.33,-.77,;-4.67,0,;-2,0,;-.67,-.77,;.66,0,;.66,1.54,;-.67,2.31,;-2,1.54,;-.67,3.85,;.67,4.62,;2,3.85,;2,2.32,;3.34,1.55,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily KQT member 1
(Homo sapiens (Human)) | BDBM50613993
(CHEMBL5286246)Show SMILES Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(cc1Cl)C#N |(3.33,-1.54,;2,-2.31,;2,-3.85,;.66,-4.62,;.66,-6.16,;-.67,-3.85,;-2,-4.62,;-2,-6.16,;-3.33,-3.86,;-3.33,-2.31,;-2,-1.54,;-.67,-2.31,;.66,-1.54,;.66,0,;-.67,.77,;-2.01,0,;-.67,2.31,;.66,3.08,;1.99,2.31,;2,.78,;3.33,.01,;.66,4.62,;.66,6.16,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| PC cid
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UniChem
| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily KQT member 1
(Homo sapiens (Human)) | BDBM585681
((R)-8-chloro-1-(2,6- dichlorophenyl)-5-(2,3- dihyd...)Show SMILES OC[C@@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wD:2.2,(-3.78,-7.53,;-4.55,-6.2,;-3.46,-5.11,;-2.12,-5.88,;-3.46,-3.57,;-2.12,-2.8,;-2.12,-1.26,;-3.46,-.49,;-3.46,1.05,;-2.12,1.82,;-2.12,3.36,;-.79,1.05,;.54,1.82,;1.88,1.05,;3.21,1.82,;4.55,1.05,;1.88,-.49,;.54,-1.26,;.54,-2.8,;-.79,-.49,;.54,4.45,;-.79,5.22,;-2.12,4.45,;-.79,6.76,;.54,7.53,;1.88,6.76,;1.88,5.22,;3.21,4.45,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily KQT member 1
(Homo sapiens (Human)) | BDBM585680
(US11530213, Example 1)Show SMILES OC[C@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wU:2.2,(-4.27,-7.27,;-4.67,-5.78,;-3.33,-5.01,;-2.25,-6.1,;-3.33,-3.47,;-2,-2.7,;-2,-1.16,;-3.33,-.39,;-3.33,1.15,;-2,1.92,;-2,3.46,;-.67,1.15,;.67,1.92,;2,1.15,;3.33,1.92,;4.67,1.15,;2,-.39,;.67,-1.16,;.67,-2.7,;-.67,-.39,;.67,4.19,;-.67,4.96,;-2,4.19,;-.67,6.5,;.67,7.27,;2,6.5,;2,4.96,;3.33,4.19,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM585681
((R)-8-chloro-1-(2,6- dichlorophenyl)-5-(2,3- dihyd...)Show SMILES OC[C@@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wD:2.2,(-3.78,-7.53,;-4.55,-6.2,;-3.46,-5.11,;-2.12,-5.88,;-3.46,-3.57,;-2.12,-2.8,;-2.12,-1.26,;-3.46,-.49,;-3.46,1.05,;-2.12,1.82,;-2.12,3.36,;-.79,1.05,;.54,1.82,;1.88,1.05,;3.21,1.82,;4.55,1.05,;1.88,-.49,;.54,-1.26,;.54,-2.8,;-.79,-.49,;.54,4.45,;-.79,5.22,;-2.12,4.45,;-.79,6.76,;.54,7.53,;1.88,6.76,;1.88,5.22,;3.21,4.45,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM585680
(US11530213, Example 1)Show SMILES OC[C@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wU:2.2,(-4.27,-7.27,;-4.67,-5.78,;-3.33,-5.01,;-2.25,-6.1,;-3.33,-3.47,;-2,-2.7,;-2,-1.16,;-3.33,-.39,;-3.33,1.15,;-2,1.92,;-2,3.46,;-.67,1.15,;.67,1.92,;2,1.15,;3.33,1.92,;4.67,1.15,;2,-.39,;.67,-1.16,;.67,-2.7,;-.67,-.39,;.67,4.19,;-.67,4.96,;-2,4.19,;-.67,6.5,;.67,7.27,;2,6.5,;2,4.96,;3.33,4.19,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human)) | BDBM585680
(US11530213, Example 1)Show SMILES OC[C@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wU:2.2,(-4.27,-7.27,;-4.67,-5.78,;-3.33,-5.01,;-2.25,-6.1,;-3.33,-3.47,;-2,-2.7,;-2,-1.16,;-3.33,-.39,;-3.33,1.15,;-2,1.92,;-2,3.46,;-.67,1.15,;.67,1.92,;2,1.15,;3.33,1.92,;4.67,1.15,;2,-.39,;.67,-1.16,;.67,-2.7,;-.67,-.39,;.67,4.19,;-.67,4.96,;-2,4.19,;-.67,6.5,;.67,7.27,;2,6.5,;2,4.96,;3.33,4.19,)| | PDB
UniProtKB/SwissProt
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GoogleScholar
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| PC cid
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UniChem
| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
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Citation and Details
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More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human)) | BDBM585681
((R)-8-chloro-1-(2,6- dichlorophenyl)-5-(2,3- dihyd...)Show SMILES OC[C@@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wD:2.2,(-3.78,-7.53,;-4.55,-6.2,;-3.46,-5.11,;-2.12,-5.88,;-3.46,-3.57,;-2.12,-2.8,;-2.12,-1.26,;-3.46,-.49,;-3.46,1.05,;-2.12,1.82,;-2.12,3.36,;-.79,1.05,;.54,1.82,;1.88,1.05,;3.21,1.82,;4.55,1.05,;1.88,-.49,;.54,-1.26,;.54,-2.8,;-.79,-.49,;.54,4.45,;-.79,5.22,;-2.12,4.45,;-.79,6.76,;.54,7.53,;1.88,6.76,;1.88,5.22,;3.21,4.45,)| | PDB
UniProtKB/SwissProt
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| PC cid
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UniChem
| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
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Citation and Details
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More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human)) | BDBM50613993
(CHEMBL5286246)Show SMILES Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(cc1Cl)C#N |(3.33,-1.54,;2,-2.31,;2,-3.85,;.66,-4.62,;.66,-6.16,;-.67,-3.85,;-2,-4.62,;-2,-6.16,;-3.33,-3.86,;-3.33,-2.31,;-2,-1.54,;-.67,-2.31,;.66,-1.54,;.66,0,;-.67,.77,;-2.01,0,;-.67,2.31,;.66,3.08,;1.99,2.31,;2,.78,;3.33,.01,;.66,4.62,;.66,6.16,)| | PDB
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More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM585680
(US11530213, Example 1)Show SMILES OC[C@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wU:2.2,(-4.27,-7.27,;-4.67,-5.78,;-3.33,-5.01,;-2.25,-6.1,;-3.33,-3.47,;-2,-2.7,;-2,-1.16,;-3.33,-.39,;-3.33,1.15,;-2,1.92,;-2,3.46,;-.67,1.15,;.67,1.92,;2,1.15,;3.33,1.92,;4.67,1.15,;2,-.39,;.67,-1.16,;.67,-2.7,;-.67,-.39,;.67,4.19,;-.67,4.96,;-2,4.19,;-.67,6.5,;.67,7.27,;2,6.5,;2,4.96,;3.33,4.19,)| | PDB
KEGG
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B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| PC cid
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UniChem
| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM585681
((R)-8-chloro-1-(2,6- dichlorophenyl)-5-(2,3- dihyd...)Show SMILES OC[C@@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl |r,wD:2.2,(-3.78,-7.53,;-4.55,-6.2,;-3.46,-5.11,;-2.12,-5.88,;-3.46,-3.57,;-2.12,-2.8,;-2.12,-1.26,;-3.46,-.49,;-3.46,1.05,;-2.12,1.82,;-2.12,3.36,;-.79,1.05,;.54,1.82,;1.88,1.05,;3.21,1.82,;4.55,1.05,;1.88,-.49,;.54,-1.26,;.54,-2.8,;-.79,-.49,;.54,4.45,;-.79,5.22,;-2.12,4.45,;-.79,6.76,;.54,7.53,;1.88,6.76,;1.88,5.22,;3.21,4.45,)| | PDB
KEGG
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| PC cid
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UniChem
| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
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Citation and Details
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More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50613993
(CHEMBL5286246)Show SMILES Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(cc1Cl)C#N |(3.33,-1.54,;2,-2.31,;2,-3.85,;.66,-4.62,;.66,-6.16,;-.67,-3.85,;-2,-4.62,;-2,-6.16,;-3.33,-3.86,;-3.33,-2.31,;-2,-1.54,;-.67,-2.31,;.66,-1.54,;.66,0,;-.67,.77,;-2.01,0,;-.67,2.31,;.66,3.08,;1.99,2.31,;2,.78,;3.33,.01,;.66,4.62,;.66,6.16,)| | PDB
KEGG
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| PC cid
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UniChem
| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50613992
(CHEMBL5282689)Show SMILES CSc1c(C#N)c(=O)c2ccc(F)cc2n1-c1c(Cl)cccc1Cl |(4.67,-.77,;3.33,0,;2,-.77,;2,-2.31,;3.33,-3.08,;4.67,-3.85,;.66,-3.08,;.66,-4.62,;-.67,-2.31,;-1.99,-3.08,;-3.33,-2.31,;-3.33,-.77,;-4.67,0,;-2,0,;-.67,-.77,;.66,0,;.66,1.54,;-.67,2.31,;-2,1.54,;-.67,3.85,;.67,4.62,;2,3.85,;2,2.32,;3.34,1.55,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| PC cid
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| | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
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More data for this
Ligand-Target Pair | |
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