Compile Data Set for Download or QSAR

Found 64 hits with Last Name = 'garner' and Initial = 'al'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chitinase (Onchocerca volvulus)	BDBM50063753 (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	468	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50565476 (CHEMBL4780117) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells by catalytic enzyme-linked click chemistry assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112655 BindingDB Entry DOI: 10.7270/Q2KS6W8F
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50565475 (CHEMBL4777401) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells by catalytic enzyme-linked click chemistry assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112655 BindingDB Entry DOI: 10.7270/Q2KS6W8F
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50525088 (CHEMBL4461497) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CNC(C)=O)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O |r| Show InChI InChI=1S/C89H146N28O24S2/c1-10-46(5)69(117-85(140)70(47(6)11-2)116-78(133)56(25-19-36-101-89(97)98)108-86(141)71(48(7)118)115-66(122)43-102-49(8)119)84(139)113-62(40-51-26-28-52(120)29-27-51)81(136)112-63(42-68(125)126)82(137)104-54(23-17-34-99-87(93)94)73(128)103-53(22-15-16-33-90)75(130)111-61(39-50-20-13-12-14-21-50)80(135)110-60(38-45(3)4)79(134)107-58(32-37-143-9)77(132)106-57(30-31-67(123)124)76(131)114-64(44-142)83(138)105-55(24-18-35-100-88(95)96)74(129)109-59(72(92)127)41-65(91)121/h12-14,20-21,26-29,45-48,53-64,69-71,118,120,142H,10-11,15-19,22-25,30-44,90H2,1-9H3,(H2,91,121)(H2,92,127)(H,102,119)(H,103,128)(H,104,137)(H,105,138)(H,106,132)(H,107,134)(H,108,141)(H,109,129)(H,110,135)(H,111,130)(H,112,136)(H,113,139)(H,114,131)(H,115,122)(H,116,133)(H,117,140)(H,123,124)(H,125,126)(H4,93,94,99)(H4,95,96,100)(H4,97,98,101)/t46-,47-,48+,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,69-,70-,71-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells by catalytic enzyme-linked click chemistry assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112655 BindingDB Entry DOI: 10.7270/Q2KS6W8F
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347553 (CHEMBL1801794) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(I)cc1 Show InChI InChI=1S/C13H8I3NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347552 (CHEMBL391125) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Br)cc1 Show InChI InChI=1S/C13H8BrI2NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347551 (CHEMBL395873) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C13H8FI2NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347554 (CHEMBL1801795) Show SMILES CC(C)c1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 Show InChI InChI=1S/C16H15I2NO2/c1-9(2)10-3-5-12(6-4-10)19-16(21)13-7-11(17)8-14(18)15(13)20/h3-9,20H,1-2H3,(H,19,21)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50063753 (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347549 (CHEMBL482487) Show SMILES Cc1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 Show InChI InChI=1S/C14H11I2NO2/c1-8-2-4-10(5-3-8)17-14(19)11-6-9(15)7-12(16)13(11)18/h2-7,18H,1H3,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50348824 (CHEMBL4177195) Show SMILES Cc1ccc(cc1Cl)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(C)c(Cl)c1 Show InChI InChI=1S/C20H18Cl2N2O4S2/c1-13-7-9-15(11-17(13)21)29(25,26)23-19-5-3-4-6-20(19)24-30(27,28)16-10-8-14(2)18(22)12-16/h3-12,23-24H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485657 (CHEMBL2146996) Show SMILES Cc1c(O)c(=S)ccn1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C19H17NOS/c1-14-19(21)18(22)11-12-20(14)13-15-7-9-17(10-8-15)16-5-3-2-4-6-16/h2-12,21H,13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485648 (CHEMBL2146995) Show SMILES Cc1c(O)c(=S)ccn1Cc1ccc(cc1)-c1ccc(F)c(F)c1 Show InChI InChI=1S/C19H15F2NOS/c1-12-19(23)18(24)8-9-22(12)11-13-2-4-14(5-3-13)15-6-7-16(20)17(21)10-15/h2-10,23H,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485651 (CHEMBL2146997) Show SMILES Cc1c(O)c(=S)ccn1Cc1ccc(cc1)-c1ccc2OCOc2c1 Show InChI InChI=1S/C20H17NO3S/c1-13-20(22)19(25)8-9-21(13)11-14-2-4-15(5-3-14)16-6-7-17-18(10-16)24-12-23-17/h2-10,22H,11-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50348830 (CHEMBL4169355) Show SMILES Cc1ccc(cc1Cl)S(=O)(=O)Nc1ccc(F)cc1NS(=O)(=O)c1ccc(C)c(Cl)c1 Show InChI InChI=1S/C20H17Cl2FN2O4S2/c1-12-3-6-15(10-17(12)21)30(26,27)24-19-8-5-14(23)9-20(19)25-31(28,29)16-7-4-13(2)18(22)11-16/h3-11,24-25H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50342407 (CHEMBL4174649) Show SMILES Cc1ccc(NS(=O)(=O)c2cccc(Cl)c2)c(NS(=O)(=O)c2cccc(Cl)c2)c1 Show InChI InChI=1S/C19H16Cl2N2O4S2/c1-13-8-9-18(22-28(24,25)16-6-2-4-14(20)11-16)19(10-13)23-29(26,27)17-7-3-5-15(21)12-17/h2-12,22-23H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485646 (CHEMBL2146998) Show SMILES Cc1c(O)c(=S)ccn1Cc1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H16FNOS/c1-13-19(22)18(23)10-11-21(13)12-14-2-4-15(5-3-14)16-6-8-17(20)9-7-16/h2-11,22H,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485653 (CHEMBL2147001) Show SMILES Cc1c(O)c(=S)ccn1Cc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H16ClNOS/c1-13-19(22)18(23)10-11-21(13)12-14-2-4-15(5-3-14)16-6-8-17(20)9-7-16/h2-11,22H,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347555 (3,5-Dibromo-2-hydroxy-N-(4-methoxyphenyl)benzamide...) Show SMILES COc1ccc(NC(=O)c2cc(Br)cc(Br)c2O)cc1 Show InChI InChI=1S/C14H11Br2NO3/c1-20-10-4-2-9(3-5-10)17-14(19)11-6-8(15)7-12(16)13(11)18/h2-7,18H,1H3,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50346949 (CHEMBL4163991) Show SMILES Clc1cccc(c1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H14Cl2N2O4S2/c19-13-5-3-7-15(11-13)27(23,24)21-17-9-1-2-10-18(17)22-28(25,26)16-8-4-6-14(20)12-16/h1-12,21-22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347548 (CHEMBL237819) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C13H8ClI2NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485647 (CHEMBL2146999) Show SMILES Cc1ccc(cc1)-c1ccc(Cn2ccc(=S)c(O)c2C)cc1 Show InChI InChI=1S/C20H19NOS/c1-14-3-7-17(8-4-14)18-9-5-16(6-10-18)13-21-12-11-19(23)20(22)15(21)2/h3-12,22H,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50342411 (CHEMBL4170052) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(F)cc1NS(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C20H19FN2O4S2/c1-14-3-8-17(9-4-14)28(24,25)22-19-12-7-16(21)13-20(19)23-29(26,27)18-10-5-15(2)6-11-18/h3-13,22-23H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485654 (CHEMBL2147000) Show SMILES COc1ccc(cc1)-c1ccc(Cn2ccc(=S)c(O)c2C)cc1 Show InChI InChI=1S/C20H19NO2S/c1-14-20(22)19(24)11-12-21(14)13-15-3-5-16(6-4-15)17-7-9-18(23-2)10-8-17/h3-12,22H,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347550 (CHEMBL484912) Show SMILES COc1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 Show InChI InChI=1S/C14H11I2NO3/c1-20-10-4-2-9(3-5-10)17-14(19)11-6-8(15)7-12(16)13(11)18/h2-7,18H,1H3,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50342408 (CHEMBL4162127) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(C)cc1NS(=O)(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H19F3N2O4S2/c1-14-6-9-17(10-7-14)31(27,28)25-19-11-8-15(2)12-20(19)26-32(29,30)18-5-3-4-16(13-18)21(22,23)24/h3-13,25-26H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50350508 (CHEMBL4165508) Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H14ClFN2O4S2/c19-13-4-3-5-16(12-13)28(25,26)22-18-7-2-1-6-17(18)21-27(23,24)15-10-8-14(20)9-11-15/h1-12,21-22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50345905 (CHEMBL4167853) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(C)cc1NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C20H19FN2O4S2/c1-14-3-8-17(9-4-14)28(24,25)22-19-12-5-15(2)13-20(19)23-29(26,27)18-10-6-16(21)7-11-18/h3-13,22-23H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50065988 (3,5-Dichloro-N-(4-chloro-phenyl)-2-hydroxy-benzami...) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C13H8Cl3NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50015094 (CHEMBL152665 | N-Hydroxy-2-phenyl-acetamide | N-hy...) Show SMILES ONC(=O)Cc1ccccc1 Show InChI InChI=1S/C8H9NO2/c10-8(9-11)6-7-4-2-1-3-5-7/h1-5,11H,6H2,(H,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50345479 (CHEMBL4172292) Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H15FN2O4S2/c19-14-10-12-16(13-11-14)27(24,25)21-18-9-5-4-8-17(18)20-26(22,23)15-6-2-1-3-7-15/h1-13,20-21H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50345477 (CHEMBL4171210) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(C)cc1NS(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C21H22N2O4S2/c1-15-4-9-18(10-5-15)28(24,25)22-20-13-8-17(3)14-21(20)23-29(26,27)19-11-6-16(2)7-12-19/h4-14,22-23H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50350836 (CHEMBL4175708) Show SMILES Cc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(NS(=O)(=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C19H16F2N2O4S2/c1-13-2-11-18(22-28(24,25)16-7-3-14(20)4-8-16)19(12-13)23-29(26,27)17-9-5-15(21)6-10-17/h2-12,22-23H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50342409 (CHEMBL4161003) Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1cccc(Br)c1 Show InChI InChI=1S/C18H14BrFN2O4S2/c19-13-4-3-5-16(12-13)28(25,26)22-18-7-2-1-6-17(18)21-27(23,24)15-10-8-14(20)9-11-15/h1-12,21-22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485655 (CHEMBL2146994) Show SMILES ONC(=O)Cc1cccc(F)c1 Show InChI InChI=1S/C8H8FNO2/c9-7-3-1-2-6(4-7)5-8(11)10-12/h1-4,12H,5H2,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50345903 (CHEMBL4167436) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C20H20N2O6S2/c1-27-15-7-11-17(12-8-15)29(23,24)21-19-5-3-4-6-20(19)22-30(25,26)18-13-9-16(28-2)10-14-18/h3-14,21-22H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50345902 (CHEMBL4176121) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C19H17FN2O5S2/c1-27-15-8-12-17(13-9-15)29(25,26)22-19-5-3-2-4-18(19)21-28(23,24)16-10-6-14(20)7-11-16/h2-13,21-22H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50342410 (CHEMBL4159534) Show SMILES Brc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C18H14Br2N2O4S2/c19-13-5-9-15(10-6-13)27(23,24)21-17-3-1-2-4-18(17)22-28(25,26)16-11-7-14(20)8-12-16/h1-12,21-22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50345475 (CHEMBL4175704) Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H14ClFN2O4S2/c19-13-5-9-15(10-6-13)27(23,24)21-17-3-1-2-4-18(17)22-28(25,26)16-11-7-14(20)8-12-16/h1-12,21-22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50350481 (CHEMBL4168929) Show SMILES Clc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H14Cl2N2O4S2/c19-13-5-9-15(10-6-13)27(23,24)21-17-3-1-2-4-18(17)22-28(25,26)16-11-7-14(20)8-12-16/h1-12,21-22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50345901 (CHEMBL4167849) Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C18H14F2N2O4S2/c19-13-5-9-15(10-6-13)27(23,24)21-17-3-1-2-4-18(17)22-28(25,26)16-11-7-14(20)8-12-16/h1-12,21-22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50346881 (CHEMBL4160599) Show SMILES Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H16Cl2N2O4S2/c1-13-2-11-18(22-28(24,25)16-7-3-14(20)4-8-16)19(12-13)23-29(26,27)17-9-5-15(21)6-10-17/h2-12,22-23H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50345904 (CHEMBL2139421) Show SMILES Cc1ccc(NS(=O)(=O)c2ccccc2)c(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C19H18N2O4S2/c1-15-12-13-18(20-26(22,23)16-8-4-2-5-9-16)19(14-15)21-27(24,25)17-10-6-3-7-11-17/h2-14,20-21H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50345478 (CHEMBL4164411) Show SMILES O=S(=O)(Nc1ccccc1NS(=O)(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C18H16N2O4S2/c21-25(22,15-9-3-1-4-10-15)19-17-13-7-8-14-18(17)20-26(23,24)16-11-5-2-6-12-16/h1-14,19-20H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Protein lin-28 homolog A (Mus musculus)	BDBM50345476 (CHEMBL4063466) Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(NC(C)=O)cc1 Show InChI InChI=1S/C22H22N4O6S2/c1-15(27)23-17-7-11-19(12-8-17)33(29,30)25-21-5-3-4-6-22(21)26-34(31,32)20-13-9-18(10-14-20)24-16(2)28/h3-14,25-26H,1-2H3,(H,23,27)(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...				ACS Med Chem Lett 9: 517-521 (2018) Article DOI: 10.1021/acsmedchemlett.8b00126 BindingDB Entry DOI: 10.7270/Q24T6MXZ
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485649 (CHEMBL1650620) Show SMILES Cc1c(O)c(=S)ccn1C Show InChI InChI=1S/C7H9NOS/c1-5-7(9)6(10)3-4-8(5)2/h3-4,9H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485656 (CHEMBL1650624) Show SMILES CCn1ccc(=S)c(O)c1C Show InChI InChI=1S/C8H11NOS/c1-3-9-5-4-7(11)8(10)6(9)2/h4-5,10H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485652 (CHEMBL1650621) Show SMILES Cn1cccc(O)c1=S Show InChI InChI=1S/C6H7NOS/c1-7-4-2-3-5(8)6(7)9/h2-4,8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485650 (CHEMBL1650623) Show SMILES CCc1c(O)c(=S)ccn1CC Show InChI InChI=1S/C9H13NOS/c1-3-7-9(11)8(12)5-6-10(7)4-2/h5-6,11H,3-4H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.92E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50525092 (CHEMBL4444144) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C68H118N22O18/c1-36(2)30-48(56(72)98)81-54(95)34-79-57(99)49(31-37(3)4)87-64(106)50(32-38(5)6)88-63(105)46(22-24-53(71)94)85-62(104)47(23-25-55(96)97)86-60(102)44(16-12-28-77-67(73)74)84-66(108)52(35-91)90-65(107)51(33-40-18-20-41(93)21-19-40)89-61(103)45(17-13-29-78-68(75)76)83-59(101)43(15-9-11-27-70)82-58(100)42(80-39(7)92)14-8-10-26-69/h18-21,36-38,42-52,91,93H,8-17,22-35,69-70H2,1-7H3,(H2,71,94)(H2,72,98)(H,79,99)(H,80,92)(H,81,95)(H,82,100)(H,83,101)(H,84,108)(H,85,104)(H,86,102)(H,87,106)(H,88,105)(H,89,103)(H,90,107)(H,96,97)(H4,73,74,77)(H4,75,76,78)/t42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to N-terminal 10His-tagged m7GDP-bound recombinant human eIF4E expressed in Escherichia coli BL21 (DE3) cells assessed as dissociati...				J Med Chem 62: 4967-4978 (2019) Article DOI: 10.1021/acs.jmedchem.9b00068 BindingDB Entry DOI: 10.7270/Q2JQ14FP
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 64 total )  |  Next  |  Last  >>

Jump to: