Compile Data Set for Download or QSAR

Found 24 hits with Last Name = 'osuma' and Initial = 'at'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513721 (CHEMBL4582071) Show SMILES CC(C)(C)CC(=O)Nc1nn2c(ccnc2c1-c1ccc(OC(F)(F)F)cc1)C(C)(C)C Show InChI InChI=1S/C23H27F3N4O2/c1-21(2,3)13-17(31)28-19-18(14-7-9-15(10-8-14)32-23(24,25)26)20-27-12-11-16(22(4,5)6)30(20)29-19/h7-12H,13H2,1-6H3,(H,28,29,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513740 (CHEMBL4455848) Show SMILES Cc1cnc2c(c(NC(=O)CCC3CCCC3)nn2c1)-c1ccc(F)c(C)c1 Show InChI InChI=1S/C22H25FN4O/c1-14-12-24-22-20(17-8-9-18(23)15(2)11-17)21(26-27(22)13-14)25-19(28)10-7-16-5-3-4-6-16/h8-9,11-13,16H,3-7,10H2,1-2H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM81199 ((Z)-but-2-enedioate;ethyl N-[2-amino-6-[(4-fluorop...) Show SMILES CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)nc1N Show InChI InChI=1S/C15H17FN4O2/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	560	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513722 (CHEMBL4462345) Show SMILES O=C(CC1CCCCC1)Nc1nn2cccnc2c1-c1ccccc1 Show InChI InChI=1S/C20H22N4O/c25-17(14-15-8-3-1-4-9-15)22-19-18(16-10-5-2-6-11-16)20-21-12-7-13-24(20)23-19/h2,5-7,10-13,15H,1,3-4,8-9,14H2,(H,22,23,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50485658 (CHEMBL2147029) Show SMILES CC(C)(C)CC(=O)Nc1nn2cccnc2c1-c1ccc(F)cc1 Show InChI InChI=1S/C18H19FN4O/c1-18(2,3)11-14(24)21-16-15(12-5-7-13(19)8-6-12)17-20-9-4-10-23(17)22-16/h4-10H,11H2,1-3H3,(H,21,22,24)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513723 (CHEMBL4554176) Show SMILES Fc1ccc(cc1)-c1c(NC(=O)C2CCCC2)nn2cccnc12 Show InChI InChI=1S/C18H17FN4O/c19-14-8-6-12(7-9-14)15-16(21-18(24)13-4-1-2-5-13)22-23-11-3-10-20-17(15)23/h3,6-11,13H,1-2,4-5H2,(H,21,22,24)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513724 (CHEMBL4556856) Show SMILES Fc1ccc(cc1)-c1c(NC(=O)CCC2CCCC2)nn2cccnc12 Show InChI InChI=1S/C20H21FN4O/c21-16-9-7-15(8-10-16)18-19(24-25-13-3-12-22-20(18)25)23-17(26)11-6-14-4-1-2-5-14/h3,7-10,12-14H,1-2,4-6,11H2,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513725 (CHEMBL4584469) Show SMILES Cc1cc(C)n2nc(NC(=O)CCC3CCCC3)c(-c3ccc(F)c(C)c3)c2n1 Show InChI InChI=1S/C23H27FN4O/c1-14-12-18(9-10-19(14)24)21-22(26-20(29)11-8-17-6-4-5-7-17)27-28-16(3)13-15(2)25-23(21)28/h9-10,12-13,17H,4-8,11H2,1-3H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513726 (CHEMBL4436737) Show SMILES Cc1cc(ccc1F)-c1c(NC(=O)CCC2CCCC2)nn2cccnc12 Show InChI InChI=1S/C21H23FN4O/c1-14-13-16(8-9-17(14)22)19-20(25-26-12-4-11-23-21(19)26)24-18(27)10-7-15-5-2-3-6-15/h4,8-9,11-13,15H,2-3,5-7,10H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513727 (CHEMBL4466756) Show SMILES Cc1cnc2c(c(NC(=O)CC3CCCC3)nn2c1)-c1ccc(F)c(C)c1 Show InChI InChI=1S/C21H23FN4O/c1-13-11-23-21-19(16-7-8-17(22)14(2)9-16)20(25-26(21)12-13)24-18(27)10-15-5-3-4-6-15/h7-9,11-12,15H,3-6,10H2,1-2H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513728 (CHEMBL4448774) Show SMILES Cc1cc(ccc1F)-c1c(NC(=O)CC2CCCC2)nn2cccnc12 Show InChI InChI=1S/C20H21FN4O/c1-13-11-15(7-8-16(13)21)18-19(24-25-10-4-9-22-20(18)25)23-17(26)12-14-5-2-3-6-14/h4,7-11,14H,2-3,5-6,12H2,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513729 (CHEMBL4558921) Show SMILES Cc1cnc2c(c(NC(=O)CC(C)(C)C)nn2c1)-c1ccc(F)c(C)c1 Show InChI InChI=1S/C20H23FN4O/c1-12-10-22-19-17(14-6-7-15(21)13(2)8-14)18(24-25(19)11-12)23-16(26)9-20(3,4)5/h6-8,10-11H,9H2,1-5H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513730 (CHEMBL4451236) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1c(NC(=O)CCC2CCCC2)nn2cccnc12 Show InChI InChI=1S/C21H21F3N4O2/c22-21(23,24)30-16-9-7-15(8-10-16)18-19(27-28-13-3-12-25-20(18)28)26-17(29)11-6-14-4-1-2-5-14/h3,7-10,12-14H,1-2,4-6,11H2,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50485660 (CHEMBL2147028) Show SMILES CC(C)(C)CC(=O)Nc1nn2cccnc2c1-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C19H19F3N4O2/c1-18(2,3)11-14(27)24-16-15(17-23-9-4-10-26(17)25-16)12-5-7-13(8-6-12)28-19(20,21)22/h4-10H,11H2,1-3H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513731 (CHEMBL4456339) Show SMILES CC(C)(C)c1ccnc2c(NC(=O)Cc3cc(F)cc(F)c3)cnn12 Show InChI InChI=1S/C18H18F2N4O/c1-18(2,3)15-4-5-21-17-14(10-22-24(15)17)23-16(25)8-11-6-12(19)9-13(20)7-11/h4-7,9-10H,8H2,1-3H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	910	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513732 (CHEMBL4448080) Show SMILES O=C(CCC1CCCCC1)Nc1nn2cccnc2c1-c1ccccc1 Show InChI InChI=1S/C21H24N4O/c26-18(13-12-16-8-3-1-4-9-16)23-20-19(17-10-5-2-6-11-17)21-22-14-7-15-25(21)24-20/h2,5-7,10-11,14-16H,1,3-4,8-9,12-13H2,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513733 (CHEMBL4460237) Show SMILES Cc1cc(C)n2nc(NC(=O)CC3CCCC3)c(-c3ccc(F)c(C)c3)c2n1 Show InChI InChI=1S/C22H25FN4O/c1-13-10-17(8-9-18(13)23)20-21(25-19(28)12-16-6-4-5-7-16)26-27-15(3)11-14(2)24-22(20)27/h8-11,16H,4-7,12H2,1-3H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513734 (CHEMBL4516269) Show SMILES FC(F)(F)c1ccc(cc1)-c1c(NC(=O)CCC2CCCC2)nn2cccnc12 Show InChI InChI=1S/C21H21F3N4O/c22-21(23,24)16-9-7-15(8-10-16)18-19(27-28-13-3-12-25-20(18)28)26-17(29)11-6-14-4-1-2-5-14/h3,7-10,12-14H,1-2,4-6,11H2,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513735 (CHEMBL4447300) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1c(NC(=O)CC2CCCC2)nn2cccnc12 Show InChI InChI=1S/C20H19F3N4O2/c21-20(22,23)29-15-8-6-14(7-9-15)17-18(26-27-11-3-10-24-19(17)27)25-16(28)12-13-4-1-2-5-13/h3,6-11,13H,1-2,4-5,12H2,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513736 (CHEMBL4592138) Show SMILES Fc1ccc(cc1)-c1c(NC(=O)CC2CCCC2)nn2cccnc12 Show InChI InChI=1S/C19H19FN4O/c20-15-8-6-14(7-9-15)17-18(23-24-11-3-10-21-19(17)24)22-16(25)12-13-4-1-2-5-13/h3,6-11,13H,1-2,4-5,12H2,(H,22,23,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513737 (CHEMBL4549421) Show SMILES Cc1cc(C)n2nc(NC(=O)CC(C)(C)C)c(-c3ccc(F)c(C)c3)c2n1 Show InChI InChI=1S/C21H25FN4O/c1-12-9-15(7-8-16(12)22)18-19(24-17(27)11-21(4,5)6)25-26-14(3)10-13(2)23-20(18)26/h7-10H,11H2,1-6H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513738 (CHEMBL4473937) Show SMILES CC(C)(C)CC(=O)Nc1nn2cccnc2c1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H19F3N4O/c1-18(2,3)11-14(27)24-16-15(17-23-9-4-10-26(17)25-16)12-5-7-13(8-6-12)19(20,21)22/h4-10H,11H2,1-3H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50513739 (CHEMBL4468366) Show SMILES Cc1cc(ccc1F)-c1c(NC(=O)CC(C)(C)C)nn2cccnc12 Show InChI InChI=1S/C19H21FN4O/c1-12-10-13(6-7-14(12)20)16-17(22-15(25)11-19(2,3)4)23-24-9-5-8-21-18(16)24/h5-10H,11H2,1-4H3,(H,22,23,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50143558 (CHEMBL41355 | EZOGABINE | N-(2-amino-4-(4-fluorobe...) Show SMILES CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)cc1N Show InChI InChI=1S/C16H18FN3O2/c1-2-22-16(21)20-15-8-7-13(9-14(15)18)19-10-11-3-5-12(17)6-4-11/h3-9,19H,2,10,18H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	n/a	4.38E+3	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.007 BindingDB Entry DOI: 10.7270/Q2Q52SZP
					More data for this Ligand-Target Pair				3D Structure (crystal)