Compile Data Set for Download or QSAR

Found 88 hits with Last Name = 'hirth' and Initial = 'bh'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561654 (CHEMBL4785914) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F |r| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Mus musculus)	BDBM50561654 (CHEMBL4785914) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F |r| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse UGT8 assessed as redcution in GalCer accumulation				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561654 (CHEMBL4785914) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F |r| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Mus musculus)	BDBM50561654 (CHEMBL4785914) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F |r| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse UGT8 assessed as redcution in SFT accumulation				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561669 (CHEMBL4787939) Show SMILES CC[C@H](C)NC(=O)OC1CCN(CC1)c1cc(c2scc(C(=O)NC)c2n1)C(F)(F)F |r| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561671 (CHEMBL4796521) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)NCCOC(F)(F)F)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561671 (CHEMBL4796521) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)NCCOC(F)(F)F)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561670 (CHEMBL4750073) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)C1CC1)C(F)(F)F |r| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561669 (CHEMBL4787939) Show SMILES CC[C@H](C)NC(=O)OC1CCN(CC1)c1cc(c2scc(C(=O)NC)c2n1)C(F)(F)F |r| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561664 (CHEMBL4776963) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)NCC1CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561670 (CHEMBL4750073) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)C1CC1)C(F)(F)F |r| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561672 (CHEMBL4750432) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N1CC(C1)OC(F)(F)F)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561663 (CHEMBL4765010) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)NC(C)C)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561663 (CHEMBL4765010) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)NC(C)C)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561672 (CHEMBL4750432) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N1CC(C1)OC(F)(F)F)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561664 (CHEMBL4776963) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)NCC1CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561665 (CHEMBL4755797) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)NC(=O)OCC1CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561665 (CHEMBL4755797) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)NC(=O)OCC1CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561667 (CHEMBL4757982) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CC(C1)NC(=O)OCC1CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561667 (CHEMBL4757982) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CC(C1)NC(=O)OCC1CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561655 (CHEMBL4760937) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC(=O)NC(C)C)CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561655 (CHEMBL4760937) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC(=O)NC(C)C)CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561657 (CHEMBL4795937) Show SMILES CCC(=O)c1csc2c(cc(nc12)N1CCN(CC(=O)NC(C)C)CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561657 (CHEMBL4795937) Show SMILES CCC(=O)c1csc2c(cc(nc12)N1CCN(CC(=O)NC(C)C)CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561658 (CHEMBL4799472) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC1)C(C)C(=O)NC1CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561662 (CHEMBL4797076) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC(O)COC(C)(C)C)CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561661 (CHEMBL4751927) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CCOC(C)C)CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561668 (CHEMBL4764180) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CC(C1)OC(=O)NCC1CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561656 (CHEMBL4747085) Show SMILES CC(C)NC(=O)CN1CCN(CC1)c1cc(c2scc(C(=O)N3CCC3)c2n1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561661 (CHEMBL4751927) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CCOC(C)C)CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561662 (CHEMBL4797076) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC(O)COC(C)(C)C)CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561658 (CHEMBL4799472) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC1)C(C)C(=O)NC1CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561659 (CHEMBL4745037) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC1)C(=O)COC(C)C)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561673 (CHEMBL4799203) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)NCCN1CCCC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561660 (CHEMBL4791074) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC(=O)C(C)(C)C)CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561666 (CHEMBL4762406) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(C1)OC(=O)NCC1CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561656 (CHEMBL4747085) Show SMILES CC(C)NC(=O)CN1CCN(CC1)c1cc(c2scc(C(=O)N3CCC3)c2n1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561659 (CHEMBL4745037) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC1)C(=O)COC(C)C)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561674 (CHEMBL4752928) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N1CC(CN(C)C)C1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Homo sapiens)	BDBM50561660 (CHEMBL4791074) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC(=O)C(C)(C)C)CC1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B15 (Homo sapiens)	BDBM50561654 (CHEMBL4785914) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT2B15 (unknown origin)				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B17 (Homo sapiens (Human))	BDBM50561654 (CHEMBL4785914) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT2B17 (unknown origin)				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 1A1 (Homo sapiens (Human))	BDBM50561654 (CHEMBL4785914) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT1A1 (unknown origin)				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 1-6 (Homo sapiens (Human))	BDBM50561654 (CHEMBL4785914) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F |r| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT1A6 (unknown origin)				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50561654 (CHEMBL4785914) Show SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of UGT2B7 (unknown origin)				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00120 BindingDB Entry DOI: 10.7270/Q2ZG6WX8
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50164966 ((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...) Show SMILES Ic1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C29H23IN2O3/c30-23-13-15-24(16-14-23)31-28(33)27-18-20-7-4-5-8-22(20)19-32(27)29(34)21-9-6-12-26(17-21)35-25-10-2-1-3-11-25/h1-17,27H,18-19H2,(H,31,33)/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	314	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR				Bioorg Med Chem Lett 15: 2087-91 (2005) Article DOI: 10.1016/j.bmcl.2005.02.041 BindingDB Entry DOI: 10.7270/Q2J965WP
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50164965 ((S)-2-(3-Isopropoxy-benzoyl)-1,2,3,4-tetrahydro-is...) Show SMILES CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(OC(C)C)c2)cc1 Show InChI InChI=1S/C31H36N2O3/c1-4-5-6-10-23-15-17-27(18-16-23)32-30(34)29-20-24-11-7-8-12-26(24)21-33(29)31(35)25-13-9-14-28(19-25)36-22(2)3/h7-9,11-19,22,29H,4-6,10,20-21H2,1-3H3,(H,32,34)/t29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.30	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR				Bioorg Med Chem Lett 15: 2087-91 (2005) Article DOI: 10.1016/j.bmcl.2005.02.041 BindingDB Entry DOI: 10.7270/Q2J965WP
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50164968 ((S)-2-(3-Cyclohexyloxy-benzoyl)-1,2,3,4-tetrahydro...) Show SMILES CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(OC3CCCCC3)c2)cc1 Show InChI InChI=1S/C34H40N2O3/c1-2-3-5-11-25-18-20-29(21-19-25)35-33(37)32-23-26-12-8-9-13-28(26)24-36(32)34(38)27-14-10-17-31(22-27)39-30-15-6-4-7-16-30/h8-10,12-14,17-22,30,32H,2-7,11,15-16,23-24H2,1H3,(H,35,37)/t32-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR				Bioorg Med Chem Lett 15: 2087-91 (2005) Article DOI: 10.1016/j.bmcl.2005.02.041 BindingDB Entry DOI: 10.7270/Q2J965WP
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50164967 ((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...) Show SMILES Brc1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C29H23BrN2O3/c30-23-13-15-24(16-14-23)31-28(33)27-18-20-7-4-5-8-22(20)19-32(27)29(34)21-9-6-12-26(17-21)35-25-10-2-1-3-11-25/h1-17,27H,18-19H2,(H,31,33)/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	292	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR				Bioorg Med Chem Lett 15: 2087-91 (2005) Article DOI: 10.1016/j.bmcl.2005.02.041 BindingDB Entry DOI: 10.7270/Q2J965WP
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50164969 ((S)-2-(3-Methoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...) Show SMILES CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(OC)c2)cc1 Show InChI InChI=1S/C29H32N2O3/c1-3-4-5-9-21-14-16-25(17-15-21)30-28(32)27-19-22-10-6-7-11-24(22)20-31(27)29(33)23-12-8-13-26(18-23)34-2/h6-8,10-18,27H,3-5,9,19-20H2,1-2H3,(H,30,32)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	176	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR				Bioorg Med Chem Lett 15: 2087-91 (2005) Article DOI: 10.1016/j.bmcl.2005.02.041 BindingDB Entry DOI: 10.7270/Q2J965WP
					More data for this Ligand-Target Pair

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