Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bile acid receptor (Homo sapiens (Human)) | BDBM50535367 (CHEMBL4456883) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535387 (CHEMBL4585144) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 830 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535369 (CHEMBL4461163) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 940 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535370 (CHEMBL4448603) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 810 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535371 (CHEMBL4455911) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 730 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535372 (CHEMBL4532035) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535373 (CHEMBL4471591) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535374 (CHEMBL4591348) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.06E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535375 (CHEMBL4592387) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 6.67E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535376 (CHEMBL4451432) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM21675 ((4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-ethy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535377 (CHEMBL4553281) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 740 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535378 (CHEMBL4562865) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535379 (CHEMBL4445722) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535380 (CHEMBL4578551) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535381 (CHEMBL4591419) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535382 (CHEMBL4588863) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 460 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535383 (CHEMBL4436469) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.93E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM21674 ((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihyd...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535384 (CHEMBL4465344) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.97E+4 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535385 (CHEMBL4455475) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 670 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535386 (CHEMBL4535914) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 3.59E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50535368 (CHEMBL4450943) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 4.37E+3 | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep... | ACS Med Chem Lett 10: 407-412 (2019) Article DOI: 10.1021/acsmedchemlett.8b00423 BindingDB Entry DOI: 10.7270/Q2WM1HXK | |||||||||||
More data for this Ligand-Target Pair |