Compile Data Set for Download or QSAR

Found 31 hits with Last Name = 'mathé' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50087242 (CHEMBL422705 | Pro-Ser-pTyr-Val-Asn-Val-Gln-Asn) Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O Show InChI InChI=1S/C40H62N11O17P/c1-18(2)31(38(61)45-23(11-12-28(41)53)34(57)48-26(40(63)64)16-30(43)55)51-36(59)25(15-29(42)54)47-39(62)32(19(3)4)50-35(58)24(14-20-7-9-21(10-8-20)68-69(65,66)67)46-37(60)27(17-52)49-33(56)22-6-5-13-44-22/h7-10,18-19,22-27,31-32,44,52H,5-6,11-17H2,1-4H3,(H2,41,53)(H2,42,54)(H2,43,55)(H,45,61)(H,46,60)(H,47,62)(H,48,57)(H,49,56)(H,50,58)(H,51,59)(H,63,64)(H2,65,66,67)/t22-,23-,24-,25-,26-,27-,31-,32-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Dissociation constant of compound was determined from affinity of compound towards Growth factor receptor bound protein 2 measured by fluorescence				Bioorg Med Chem Lett 10: 669-72 (2000) BindingDB Entry DOI: 10.7270/Q2B857BR
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194161 ((2R,3R,5S)-1-(5-(diphosphoryloxymethyl)-3-hydroxyt...) Show SMILES O[C@@H]1C[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C9H14N2O11P2/c12-6-3-5(4-20-24(18,19)22-23(15,16)17)21-8(6)11-2-1-7(13)10-9(11)14/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50087244 (Ac-Pro-Phe-pTyr-Val-Asn-Val-Pro-NH2 | CHEMBL237124...) Show SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C44H62N9O13P/c1-24(2)36(43(61)49-32(23-35(45)55)41(59)51-37(25(3)4)44(62)53-20-9-13-33(53)38(46)56)50-40(58)31(22-28-15-17-29(18-16-28)66-67(63,64)65)47-39(57)30(21-27-11-7-6-8-12-27)48-42(60)34-14-10-19-52(34)26(5)54/h6-8,11-12,15-18,24-25,30-34,36-37H,9-10,13-14,19-23H2,1-5H3,(H2,45,55)(H2,46,56)(H,47,57)(H,48,60)(H,49,61)(H,50,58)(H,51,59)(H2,63,64,65)/t30-,31-,32-,33-,34-,36-,37-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Dissociation constant of compound was determined from affinity of compound towards Growth factor receptor bound protein 2 measured by fluorescence				Bioorg Med Chem Lett 10: 669-72 (2000) BindingDB Entry DOI: 10.7270/Q2B857BR
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50087245 (CHEMBL345170 | Pro-Ser-Pmp-Val-Asn-Val-Gln-Asn) Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O Show InChI InChI=1S/C41H64N11O16P/c1-19(2)32(39(62)46-24(11-12-29(42)54)35(58)49-27(41(64)65)16-31(44)56)52-37(60)26(15-30(43)55)48-40(63)33(20(3)4)51-36(59)25(14-21-7-9-22(10-8-21)18-69(66,67)68)47-38(61)28(17-53)50-34(57)23-6-5-13-45-23/h7-10,19-20,23-28,32-33,45,53H,5-6,11-18H2,1-4H3,(H2,42,54)(H2,43,55)(H2,44,56)(H,46,62)(H,47,61)(H,48,63)(H,49,58)(H,50,57)(H,51,59)(H,52,60)(H,64,65)(H2,66,67,68)/t23-,24-,25-,26-,27-,28-,32-,33-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Dissociation constant of compound was determined from affinity of compound towards Growth factor receptor bound protein 2 measured by fluorescence				Bioorg Med Chem Lett 10: 669-72 (2000) BindingDB Entry DOI: 10.7270/Q2B857BR
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194146 ((2R,3S,4R,5R)-1-(5-(diphosphoryloxymethyl)-3-fluor...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@H]1F)n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C9H13FN2O11P2/c10-6-7(14)4(3-21-25(19,20)23-24(16,17)18)22-8(6)12-2-1-5(13)11-9(12)15/h1-2,4,6-8,14H,3H2,(H,19,20)(H,11,13,15)(H2,16,17,18)/t4-,6+,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50118239 (CHEMBL130266 | UDP | Uridine diphosphate | uridine...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194147 (4-Thio-UDP | CHEMBL384992 | [(2R,3S,4R,5R)-3,4-dih...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1ccc(=S)[nH]c1=O Show InChI InChI=1S/C9H14N2O11P2S/c12-6-4(3-20-24(18,19)22-23(15,16)17)21-8(7(6)13)11-2-1-5(25)10-9(11)14/h1-2,4,6-8,12-13H,3H2,(H,18,19)(H,10,14,25)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194148 ((2R,3R,4S,5R)-4-(allylthio)-1-(3,4-dihydroxy-5-(di...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(SCC=C)nc1=O Show InChI InChI=1S/C12H18N2O11P2S/c1-2-5-28-8-3-4-14(12(17)13-8)11-10(16)9(15)7(24-11)6-23-27(21,22)25-26(18,19)20/h2-4,7,9-11,15-16H,1,5-6H2,(H,21,22)(H2,18,19,20)/t7-,9-,10-,11-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	560	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM92459 (CHEMBL384759 | GDP | Guanosine Diphosphate) Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50368125 (ADENOSINE DIPHOSPHATE | ADP) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194150 ((1S,3R,4R,5S)-1-(4-hydroxy-1-(diphosphoryloxymethy...) Show SMILES O[C@@H]1[C@@H]2C[C@]2(COP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C10H14N2O11P2/c13-6-1-2-12(9(15)11-6)8-7(14)5-3-10(5,22-8)4-21-25(19,20)23-24(16,17)18/h1-2,5,7-8,14H,3-4H2,(H,19,20)(H,11,13,15)(H2,16,17,18)/t5-,7+,8+,10+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194152 ((2R,3R,4S,5R)-1-(3,4-dihydroxy-5-(diphosphoryloxym...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1c(I)cc(=O)[nH]c1=O Show InChI InChI=1S/C9H13IN2O12P2/c10-4-1-5(13)11-9(16)12(4)8-7(15)6(14)3(23-8)2-22-26(20,21)24-25(17,18)19/h1,3,6-8,14-15H,2H2,(H,20,21)(H,11,13,16)(H2,17,18,19)/t3-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194153 (5'-CDP | CDP | CHEMBL425252 | Cytidine | Cytidine ...) Show SMILES Nc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 Show InChI InChI=1S/C9H15N3O11P2/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194151 (CHEMBL212090 | [(2R,3S,5S)-5-(2,4-dioxo-3,4-dihydr...) Show SMILES O[C@H]1C[C@]2(CC2[C@@H]1COP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C11H16N2O10P2/c14-8-4-11(13-2-1-9(15)12-10(13)16)3-7(11)6(8)5-22-25(20,21)23-24(17,18)19/h1-2,6-8,14H,3-5H2,(H,20,21)(H,12,15,16)(H2,17,18,19)/t6-,7?,8-,11-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194154 ((2R,3R,4S,5R)-2-(1-(3,4-dihydroxy-5-(diphosphorylo...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(SCC(O)=O)nc1=O Show InChI InChI=1S/C11H16N2O13P2S/c14-7(15)4-29-6-1-2-13(11(18)12-6)10-9(17)8(16)5(25-10)3-24-28(22,23)26-27(19,20)21/h1-2,5,8-10,16-17H,3-4H2,(H,14,15)(H,22,23)(H2,19,20,21)/t5-,8-,9-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194155 ((2R,3R,4S,5R)-2-(1-(3,4-dihydroxy-5-(diphosphorylo...) Show SMILES NC(=O)CSc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 Show InChI InChI=1S/C11H17N3O12P2S/c12-6(15)4-29-7-1-2-14(11(18)13-7)10-9(17)8(16)5(25-10)3-24-28(22,23)26-27(19,20)21/h1-2,5,8-10,16-17H,3-4H2,(H2,12,15)(H,22,23)(H2,19,20,21)/t5-,8-,9-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50179185 (((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H...) Show SMILES O[C@H]1C[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C9H14N2O11P2/c12-5-3-8(11-2-1-7(13)10-9(11)14)21-6(5)4-20-24(18,19)22-23(15,16)17/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194156 ((2R,3R,4S,5R)-4-(benzylthio)-1-(3,4-dihydroxy-5-(d...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(SCc2ccccc2)nc1=O Show InChI InChI=1S/C16H20N2O11P2S/c19-13-11(8-27-31(25,26)29-30(22,23)24)28-15(14(13)20)18-7-6-12(17-16(18)21)32-9-10-4-2-1-3-5-10/h1-7,11,13-15,19-20H,8-9H2,(H,25,26)(H2,22,23,24)/t11-,13-,14-,15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194157 (CHEMBL378445 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C18H24N4O17P2/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(37-15)5-35-40(31,32)39-41(33,34)36-6-8-12(26)14(28)16(38-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,19,23,29)(H,20,24,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194158 ((2R,3R,4S,5R)-3-(1-(3,4-dihydroxy-5-(diphosphorylo...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(SCCC(O)=O)nc1=O Show InChI InChI=1S/C12H18N2O13P2S/c15-8(16)2-4-30-7-1-3-14(12(19)13-7)11-10(18)9(17)6(26-11)5-25-29(23,24)27-28(20,21)22/h1,3,6,9-11,17-18H,2,4-5H2,(H,15,16)(H,23,24)(H2,20,21,22)/t6-,9-,10-,11-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194160 ((2R,3R,4S,5R)-1-(3,4-dihydroxy-5-(diphosphoryloxym...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=S Show InChI InChI=1S/C9H14N2O11P2S/c12-5-1-2-11(9(25)10-5)8-7(14)6(13)4(21-8)3-20-24(18,19)22-23(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,10,12,25)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 4 (Homo sapiens (Human))	BDBM50194161 ((2R,3R,5S)-1-(5-(diphosphoryloxymethyl)-3-hydroxyt...) Show SMILES O[C@@H]1C[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C9H14N2O11P2/c12-6-3-5(4-20-24(18,19)22-23(15,16)17)21-8(6)11-2-1-7(13)10-9(11)14/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y4 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194159 ((2R,3R,4S,5R)-1-(3,4-dihydroxy-5-(diphosphoryloxym...) Show SMILES CCCCCCSc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 Show InChI InChI=1S/C15H26N2O11P2S/c1-2-3-4-5-8-31-11-6-7-17(15(20)16-11)14-13(19)12(18)10(27-14)9-26-30(24,25)28-29(21,22)23/h6-7,10,12-14,18-19H,2-5,8-9H2,1H3,(H,24,25)(H2,21,22,23)/t10-,12-,13-,14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194162 (3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dion...) Show SMILES Cn1c(=O)ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c1=O Show InChI InChI=1S/C10H16N2O12P2/c1-11-6(13)2-3-12(10(11)16)9-8(15)7(14)5(23-9)4-22-26(20,21)24-25(17,18)19/h2-3,5,7-9,14-15H,4H2,1H3,(H,20,21)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194163 ((2R,3R,4S,5R)-1-(3-amino-5-(diphosphoryloxymethyl)...) Show SMILES N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C9H15N3O11P2/c10-6-7(14)4(3-21-25(19,20)23-24(16,17)18)22-8(6)12-2-1-5(13)11-9(12)15/h1-2,4,6-8,14H,3,10H2,(H,19,20)(H,11,13,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194164 ((2R,3R,4S,5R)-1-(3,4-dihydroxy-5-(diphosphoryloxym...) Show SMILES CSc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 Show InChI InChI=1S/C10H16N2O11P2S/c1-26-6-2-3-12(10(15)11-6)9-8(14)7(13)5(22-9)4-21-25(19,20)23-24(16,17)18/h2-3,5,7-9,13-14H,4H2,1H3,(H,19,20)(H2,16,17,18)/t5-,7-,8-,9-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 2 (Homo sapiens (Human))	BDBM50194161 ((2R,3R,5S)-1-(5-(diphosphoryloxymethyl)-3-hydroxyt...) Show SMILES O[C@@H]1C[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C9H14N2O11P2/c12-6-3-5(4-20-24(18,19)22-23(15,16)17)21-8(6)11-2-1-7(13)10-9(11)14/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194167 ((2R,3R,4S,5R)-4-(1-(3,4-dihydroxy-5-(diphosphorylo...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(SCCCC(O)=O)nc1=O Show InChI InChI=1S/C13H20N2O13P2S/c16-9(17)2-1-5-31-8-3-4-15(13(20)14-8)12-11(19)10(18)7(27-12)6-26-30(24,25)28-29(21,22)23/h3-4,7,10-12,18-19H,1-2,5-6H2,(H,16,17)(H,24,25)(H2,21,22,23)/t7-,10-,11-,12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194166 ((2R,3R,4S,5R)-1-(3-azido-5-(diphosphoryloxymethyl)...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1N=[N+]=[N-])n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C9H13N5O11P2/c10-13-12-6-7(16)4(3-23-27(21,22)25-26(18,19)20)24-8(6)14-2-1-5(15)11-9(14)17/h1-2,4,6-8,16H,3H2,(H,21,22)(H,11,15,17)(H2,18,19,20)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Homo sapiens (Human))	BDBM50194165 ((2R,3R,4S,5R)-1-(3,4-dihydroxy-5-(diphosphoryloxym...) Show SMILES CCSc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 Show InChI InChI=1S/C11H18N2O11P2S/c1-2-27-7-3-4-13(11(16)12-7)10-9(15)8(14)6(23-10)5-22-26(20,21)24-25(17,18)19/h3-4,6,8-10,14-15H,2,5H2,1H3,(H,20,21)(H2,17,18,19)/t6-,8-,9-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP production				J Med Chem 49: 5532-43 (2006) Article DOI: 10.1021/jm060485n BindingDB Entry DOI: 10.7270/Q2ZC83NW
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50087243 (CHEMBL436789 | Pro-Ser-F2Pmp-Val-Asn-Val-Gln-Asn) Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O Show InChI InChI=1S/C41H62F2N11O16P/c1-18(2)31(38(64)48-23(11-12-28(44)56)34(60)51-26(40(66)67)16-30(46)58)54-36(62)25(15-29(45)57)50-39(65)32(19(3)4)53-35(61)24(14-20-7-9-21(10-8-20)41(42,43)71(68,69)70)49-37(63)27(17-55)52-33(59)22-6-5-13-47-22/h7-10,18-19,22-27,31-32,47,55H,5-6,11-17H2,1-4H3,(H2,44,56)(H2,45,57)(H2,46,58)(H,48,64)(H,49,63)(H,50,65)(H,51,60)(H,52,59)(H,53,61)(H,54,62)(H,66,67)(H2,68,69,70)/t22-,23-,24-,25-,26-,27-,31-,32-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Dissociation constant of compound was determined from affinity of compound towards Growth factor receptor bound protein 2 measured by fluorescence				Bioorg Med Chem Lett 10: 669-72 (2000) BindingDB Entry DOI: 10.7270/Q2B857BR
					More data for this Ligand-Target Pair