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Compile Data Set for Download or QSAR

Found 5 hits with Last Name = 'mendoza' and Initial = 'cs'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Mus musculus (Mouse))
BDBM50237231
PNG
(CHEMBL4063130)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc2-[#8]-[#6](-[#6]-[#6](=O)-c2c1-[#8])-c1ccc(-[#8])c(-[#8])c1-[#6]\[#6]=[#6](\[#6])-[#6]
Show InChI InChI=1S/C25H28O6/c1-13(2)5-7-16-15(9-10-18(26)24(16)29)21-12-20(28)23-22(31-21)11-19(27)17(25(23)30)8-6-14(3)4/h5-6,9-11,21,26-27,29-30H,7-8,12H2,1-4H3
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 750n/an/an/an/an/an/a



Universidad Nacional de C£rdoba

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs


Bioorg Med Chem Lett 27: 1789-1794 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.058
BindingDB Entry DOI: 10.7270/Q2MW2KDB
More data for this
Ligand-Target Pair
Tyrosinase


(Mus musculus (Mouse))
BDBM50237232
PNG
(CHEMBL516671)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(-[#8])c2-[#6](=O)-[#6]-[#6](-[#8]-c12)-c1cc(c(-[#8])cc1-[#8])C([#6])([#6])[#6]=[#6]
Show InChI InChI=1S/C25H28O6/c1-6-25(4,5)16-9-15(18(27)10-19(16)28)22-12-21(30)23-20(29)11-17(26)14(24(23)31-22)8-7-13(2)3/h6-7,9-11,22,26-29H,1,8,12H2,2-5H3
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Universidad Nacional de C£rdoba

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs


Bioorg Med Chem Lett 27: 1789-1794 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.058
BindingDB Entry DOI: 10.7270/Q2MW2KDB
More data for this
Ligand-Target Pair
Tyrosinase


(Mus musculus (Mouse))
BDBM50237229
PNG
(CHEMBL4083227)
Show SMILES [#6]-[#8]-c1cc(-[#8])c(cc1-[#6]-1-[#6]-[#6](=O)-c2c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])cc2-[#8]-1)C([#6])([#6])[#6]=[#6]
Show InChI InChI=1S/C26H30O6/c1-7-26(4,5)17-10-16(21(31-6)12-19(17)28)22-13-20(29)24-23(32-22)11-18(27)15(25(24)30)9-8-14(2)3/h7-8,10-12,22,27-28,30H,1,9,13H2,2-6H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Universidad Nacional de C£rdoba

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs


Bioorg Med Chem Lett 27: 1789-1794 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.058
BindingDB Entry DOI: 10.7270/Q2MW2KDB
More data for this
Ligand-Target Pair
Tyrosinase


(Mus musculus (Mouse))
BDBM50237230
PNG
(CHEMBL4101226)
Show SMILES [#6]-[#8]-c1cc(-[#8])c(cc1-[#6]-1-[#6]-[#6](=O)-c2c(-[#8])cc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2-[#8]-1)C([#6])([#6])[#6]=[#6]
Show InChI InChI=1S/C26H30O6/c1-7-26(4,5)17-10-16(22(31-6)12-19(17)28)23-13-21(30)24-20(29)11-18(27)15(25(24)32-23)9-8-14(2)3/h7-8,10-12,23,27-29H,1,9,13H2,2-6H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Universidad Nacional de C£rdoba

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs


Bioorg Med Chem Lett 27: 1789-1794 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.058
BindingDB Entry DOI: 10.7270/Q2MW2KDB
More data for this
Ligand-Target Pair
Tyrosinase


(Mus musculus (Mouse))
BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
UniProtKB/SwissProt

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CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.00E+6n/an/an/an/an/an/a



Universidad Nacional de C£rdoba

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs


Bioorg Med Chem Lett 27: 1789-1794 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.058
BindingDB Entry DOI: 10.7270/Q2MW2KDB
More data for this
Ligand-Target Pair