Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50057354 (5-Methyl-5,6,7,8,9,10-hexahydro-cyclohepta[b]indol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université H. Poincaré Curated by ChEMBL | Assay Description Inhibitory concentration against 5-lipoxygenase from isolated rabbit granulocytes | J Med Chem 40: 1201-10 (1997) Article DOI: 10.1021/jm960542k BindingDB Entry DOI: 10.7270/Q2G73CSC | |||||||||||
More data for this Ligand-Target Pair |