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Found 1453 hits with Last Name = 'raveendra-panickar' and Initial = 'd'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ephrin type-A receptor 4 [1-949,A922V]


(Homo sapiens (Human))
BDBM11985
PNG
(4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic a...)
Show SMILES Cc1ccc(C)n1-c1ccc(C(O)=O)c(O)c1
Show InChI InChI=1S/C13H13NO3/c1-8-3-4-9(2)14(8)10-5-6-11(13(16)17)12(15)7-10/h3-7,15H,1-2H3,(H,16,17)
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n/an/a 1.30E+3n/an/an/an/a7.5n/a



Sanford-Burnham Medical Research Institute



Assay Description
Protein A-coasted wells (from Pierce Biotechnology) were used to immobilize Eph receptor Fc fusion proteins (from R&D systems)incubated at 1 ug/ml in...


Chem Biol Drug Des 78: 667-78 (2011)


Article DOI: 10.1111/j.1747-0285.2011.01199.x
BindingDB Entry DOI: 10.7270/Q2FN14QN
More data for this
Ligand-Target Pair
Ephrin type-A receptor 4 [1-949,A922V]


(Homo sapiens (Human))
BDBM82187
PNG
(Salicylic acid derivative, 76D10)
Show SMILES OC(=O)c1cc(ccc1O)-c1ccc(\C=C\C(=O)\C=C\c2ccc(o2)-c2ccc(O)c(c2)C(O)=O)o1
Show InChI InChI=1S/C27H18O9/c28-17(3-5-18-7-11-24(35-18)15-1-9-22(29)20(13-15)26(31)32)4-6-19-8-12-25(36-19)16-2-10-23(30)21(14-16)27(33)34/h1-14,29-30H,(H,31,32)(H,33,34)/b5-3+,6-4+
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n/an/a 2.60E+3n/an/an/an/a7.5n/a



Sanford-Burnham Medical Research Institute



Assay Description
Protein A-coasted wells (from Pierce Biotechnology) were used to immobilize Eph receptor Fc fusion proteins (from R&D systems)incubated at 1 ug/ml in...


Chem Biol Drug Des 78: 667-78 (2011)


Article DOI: 10.1111/j.1747-0285.2011.01199.x
BindingDB Entry DOI: 10.7270/Q2FN14QN
More data for this
Ligand-Target Pair
Ephrin type-A receptor 4 [1-949,A922V]


(Homo sapiens (Human))
BDBM82190
PNG
(Salicylic acid derivative, compound 2)
Show SMILES Cc1ccc(C)n1-c1ccc(O)c(c1)C(O)=O
Show InChI InChI=1S/C13H13NO3/c1-8-3-4-9(2)14(8)10-5-6-12(15)11(7-10)13(16)17/h3-7,15H,1-2H3,(H,16,17)
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n/an/a 1.00E+4n/an/an/an/a7.5n/a



Sanford-Burnham Medical Research Institute



Assay Description
Protein A-coasted wells (from Pierce Biotechnology) were used to immobilize Eph receptor Fc fusion proteins (from R&D systems)incubated at 1 ug/ml in...


Chem Biol Drug Des 78: 667-78 (2011)


Article DOI: 10.1111/j.1747-0285.2011.01199.x
BindingDB Entry DOI: 10.7270/Q2FN14QN
More data for this
Ligand-Target Pair
Ephrin type-A receptor 4 [1-949,A922V]


(Homo sapiens (Human))
BDBM82188
PNG
(Salicylic acid derivative, 76A5)
Show SMILES OC(=O)\C=C\c1ccc(o1)-c1ccc(O)c(c1)C(O)=O
Show InChI InChI=1S/C14H10O6/c15-11-4-1-8(7-10(11)14(18)19)12-5-2-9(20-12)3-6-13(16)17/h1-7,15H,(H,16,17)(H,18,19)/b6-3+
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n/an/a>5.00E+5n/an/an/an/a7.5n/a



Sanford-Burnham Medical Research Institute



Assay Description
Protein A-coasted wells (from Pierce Biotechnology) were used to immobilize Eph receptor Fc fusion proteins (from R&D systems)incubated at 1 ug/ml in...


Chem Biol Drug Des 78: 667-78 (2011)


Article DOI: 10.1111/j.1747-0285.2011.01199.x
BindingDB Entry DOI: 10.7270/Q2FN14QN
More data for this
Ligand-Target Pair
Ephrin type-A receptor 4 [1-949,A922V]


(Homo sapiens (Human))
BDBM82189
PNG
(Salicylic acid derivative, 76B8)
Show SMILES OC(=O)c1ccc(o1)-c1ccc(O)c(c1)C(O)=O
Show InChI InChI=1S/C12H8O6/c13-8-2-1-6(5-7(8)11(14)15)9-3-4-10(18-9)12(16)17/h1-5,13H,(H,14,15)(H,16,17)
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n/an/a>5.00E+5n/an/an/an/a7.5n/a



Sanford-Burnham Medical Research Institute



Assay Description
Protein A-coasted wells (from Pierce Biotechnology) were used to immobilize Eph receptor Fc fusion proteins (from R&D systems)incubated at 1 ug/ml in...


Chem Biol Drug Des 78: 667-78 (2011)


Article DOI: 10.1111/j.1747-0285.2011.01199.x
BindingDB Entry DOI: 10.7270/Q2FN14QN
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393728
PNG
(US10597367, Example 18 | US9969726, Example 18)
Show SMILES OC(=O)c1cc(ccc1F)-c1ccccc1-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H14FNO2S/c23-19-11-10-15(12-18(19)22(25)26)16-8-4-5-9-17(16)20-13-27-21(24-20)14-6-2-1-3-7-14/h1-13H,(H,25,26)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393728
PNG
(US10597367, Example 18 | US9969726, Example 18)
Show SMILES OC(=O)c1cc(ccc1F)-c1ccccc1-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H14FNO2S/c23-19-11-10-15(12-18(19)22(25)26)16-8-4-5-9-17(16)20-13-27-21(24-20)14-6-2-1-3-7-14/h1-13H,(H,25,26)
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n/an/an/an/a>3.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393729
PNG
(US10597367, Example 19 | US9969726, Example 19)
Show SMILES COc1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H16FNOS/c1-25-21-13-17(10-11-19(21)23)16-8-5-9-18(12-16)20-14-26-22(24-20)15-6-3-2-4-7-15/h2-14H,1H3
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n/an/an/an/a 3.67E+3n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393729
PNG
(US10597367, Example 19 | US9969726, Example 19)
Show SMILES COc1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H16FNOS/c1-25-21-13-17(10-11-19(21)23)16-8-5-9-18(12-16)20-14-26-22(24-20)15-6-3-2-4-7-15/h2-14H,1H3
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n/an/an/an/a 1.55E+3n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393729
PNG
(US10597367, Example 19 | US9969726, Example 19)
Show SMILES COc1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H16FNOS/c1-25-21-13-17(10-11-19(21)23)16-8-5-9-18(12-16)20-14-26-22(24-20)15-6-3-2-4-7-15/h2-14H,1H3
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n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393729
PNG
(US10597367, Example 19 | US9969726, Example 19)
Show SMILES COc1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H16FNOS/c1-25-21-13-17(10-11-19(21)23)16-8-5-9-18(12-16)20-14-26-22(24-20)15-6-3-2-4-7-15/h2-14H,1H3
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n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393730
PNG
(US9969726, Example 20)
Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-
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n/an/an/an/a>3.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393730
PNG
(US9969726, Example 20)
Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393730
PNG
(US9969726, Example 20)
Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-
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n/an/an/an/a>3.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393730
PNG
(US9969726, Example 20)
Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393731
PNG
(US10597367, Example 21 | US9969726, Example 21)
Show SMILES Clc1cccc(c1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-5-9-17(13-19)16-8-4-10-18(12-16)20-14-24-21(23-20)15-6-2-1-3-7-15/h1-14H
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n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393731
PNG
(US10597367, Example 21 | US9969726, Example 21)
Show SMILES Clc1cccc(c1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-5-9-17(13-19)16-8-4-10-18(12-16)20-14-24-21(23-20)15-6-2-1-3-7-15/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393731
PNG
(US10597367, Example 21 | US9969726, Example 21)
Show SMILES Clc1cccc(c1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-5-9-17(13-19)16-8-4-10-18(12-16)20-14-24-21(23-20)15-6-2-1-3-7-15/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393731
PNG
(US10597367, Example 21 | US9969726, Example 21)
Show SMILES Clc1cccc(c1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-5-9-17(13-19)16-8-4-10-18(12-16)20-14-24-21(23-20)15-6-2-1-3-7-15/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
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n/an/an/an/a>3.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
PDB

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n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
PDB

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n/an/an/an/a>3.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393733
PNG
(US10597367, Example 23 | US9969726, Example 23)
Show SMILES COc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H17NOS/c1-24-21-13-6-5-12-19(21)17-10-7-11-18(14-17)20-15-25-22(23-20)16-8-3-2-4-9-16/h2-15H,1H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393733
PNG
(US10597367, Example 23 | US9969726, Example 23)
Show SMILES COc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H17NOS/c1-24-21-13-6-5-12-19(21)17-10-7-11-18(14-17)20-15-25-22(23-20)16-8-3-2-4-9-16/h2-15H,1H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393733
PNG
(US10597367, Example 23 | US9969726, Example 23)
Show SMILES COc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H17NOS/c1-24-21-13-6-5-12-19(21)17-10-7-11-18(14-17)20-15-25-22(23-20)16-8-3-2-4-9-16/h2-15H,1H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393733
PNG
(US10597367, Example 23 | US9969726, Example 23)
Show SMILES COc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H17NOS/c1-24-21-13-6-5-12-19(21)17-10-7-11-18(14-17)20-15-25-22(23-20)16-8-3-2-4-9-16/h2-15H,1H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393734
PNG
(US10597367, Example 24 | US9969726, Example 24)
Show SMILES Clc1ccc(cc1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-9-15(10-12-19)17-7-4-8-18(13-17)20-14-24-21(23-20)16-5-2-1-3-6-16/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393734
PNG
(US10597367, Example 24 | US9969726, Example 24)
Show SMILES Clc1ccc(cc1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-9-15(10-12-19)17-7-4-8-18(13-17)20-14-24-21(23-20)16-5-2-1-3-6-16/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393734
PNG
(US10597367, Example 24 | US9969726, Example 24)
Show SMILES Clc1ccc(cc1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-9-15(10-12-19)17-7-4-8-18(13-17)20-14-24-21(23-20)16-5-2-1-3-6-16/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393734
PNG
(US10597367, Example 24 | US9969726, Example 24)
Show SMILES Clc1ccc(cc1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-9-15(10-12-19)17-7-4-8-18(13-17)20-14-24-21(23-20)16-5-2-1-3-6-16/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393735
PNG
(US10597367, Example 25 | US9969726, Example 25)
Show SMILES OC(=O)c1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15NO2S/c24-22(25)19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-26-21(23-20)15-7-2-1-3-8-15/h1-14H,(H,24,25)
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393735
PNG
(US10597367, Example 25 | US9969726, Example 25)
Show SMILES OC(=O)c1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15NO2S/c24-22(25)19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-26-21(23-20)15-7-2-1-3-8-15/h1-14H,(H,24,25)
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393735
PNG
(US10597367, Example 25 | US9969726, Example 25)
Show SMILES OC(=O)c1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15NO2S/c24-22(25)19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-26-21(23-20)15-7-2-1-3-8-15/h1-14H,(H,24,25)
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393735
PNG
(US10597367, Example 25 | US9969726, Example 25)
Show SMILES OC(=O)c1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15NO2S/c24-22(25)19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-26-21(23-20)15-7-2-1-3-8-15/h1-14H,(H,24,25)
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393736
PNG
(US10597367, Example 26 | US9969726, Example 26)
Show SMILES Clc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-24-21(23-20)15-7-2-1-3-8-15/h1-14H
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393736
PNG
(US10597367, Example 26 | US9969726, Example 26)
Show SMILES Clc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-24-21(23-20)15-7-2-1-3-8-15/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393736
PNG
(US10597367, Example 26 | US9969726, Example 26)
Show SMILES Clc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-24-21(23-20)15-7-2-1-3-8-15/h1-14H
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393736
PNG
(US10597367, Example 26 | US9969726, Example 26)
Show SMILES Clc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-24-21(23-20)15-7-2-1-3-8-15/h1-14H
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393737
PNG
(US10597367, Example 27 | US9969726, Example 27)
Show SMILES Fc1ccc(cc1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C15H10FNS/c16-13-8-6-11(7-9-13)14-10-18-15(17-14)12-4-2-1-3-5-12/h1-10H
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393737
PNG
(US10597367, Example 27 | US9969726, Example 27)
Show SMILES Fc1ccc(cc1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C15H10FNS/c16-13-8-6-11(7-9-13)14-10-18-15(17-14)12-4-2-1-3-5-12/h1-10H
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393737
PNG
(US10597367, Example 27 | US9969726, Example 27)
Show SMILES Fc1ccc(cc1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C15H10FNS/c16-13-8-6-11(7-9-13)14-10-18-15(17-14)12-4-2-1-3-5-12/h1-10H
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393737
PNG
(US10597367, Example 27 | US9969726, Example 27)
Show SMILES Fc1ccc(cc1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C15H10FNS/c16-13-8-6-11(7-9-13)14-10-18-15(17-14)12-4-2-1-3-5-12/h1-10H
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
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Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393739
PNG
(US10597367, Example 29 | US9969726, Example 29)
Show SMILES COc1ccc(cc1OC)-c1nc(cs1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H19NO2S/c1-25-21-12-11-19(14-22(21)26-2)23-24-20(15-27-23)18-10-6-9-17(13-18)16-7-4-3-5-8-16/h3-15H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.58E+3n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393739
PNG
(US10597367, Example 29 | US9969726, Example 29)
Show SMILES COc1ccc(cc1OC)-c1nc(cs1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H19NO2S/c1-25-21-12-11-19(14-22(21)26-2)23-24-20(15-27-23)18-10-6-9-17(13-18)16-7-4-3-5-8-16/h3-15H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.10E+3n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393739
PNG
(US10597367, Example 29 | US9969726, Example 29)
Show SMILES COc1ccc(cc1OC)-c1nc(cs1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H19NO2S/c1-25-21-12-11-19(14-22(21)26-2)23-24-20(15-27-23)18-10-6-9-17(13-18)16-7-4-3-5-8-16/h3-15H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 4.02E+3n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
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