Compile Data Set for Download or QSAR

Found 87 hits with Last Name = 'st?phanie' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577554 (2-[[1-[(1 R)-2,2-Difluoro-1-methyl-ethyl]-3-(oxeta...) Show SMILES C[C@H](C(F)F)n1cc(Nc2ncc3cc(C#N)n([C@H]4COC[C@@H]4C)c3n2)c(OC2COC2)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577560 (7-[(3R,4R)-4-Methyltetrahydrofuran-3-yl]-2-[[1-(ox...) Show SMILES C[C@H](ON(c1cnn(c1)C1COC1)c1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1)C(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577560 (7-[(3R,4R)-4-Methyltetrahydrofuran-3-yl]-2-[[1-(ox...) Show SMILES C[C@H](ON(c1cnn(c1)C1COC1)c1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577575 (2-((1-Methyl-3-(oxetan-3-yloxy)-1 H-pyrazol-4-yl)a...) Show SMILES C[C@@H]1COC[C@H]1n1c(cc2cnc(Nc3cn(C)nc3OC3COC3)nc12)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577554 (2-[[1-[(1 R)-2,2-Difluoro-1-methyl-ethyl]-3-(oxeta...) Show SMILES C[C@H](C(F)F)n1cc(Nc2ncc3cc(C#N)n([C@H]4COC[C@@H]4C)c3n2)c(OC2COC2)n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577571 (2-((1-Methyl-3-(((R)-1 ,1 ,1-trifluoropropan-2-yl)...) Show SMILES C[C@@H](Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577571 (2-((1-Methyl-3-(((R)-1 ,1 ,1-trifluoropropan-2-yl)...) Show SMILES C[C@@H](Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1)C(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577564 (2-[[1-(Methylsulfonylmethyl)-3-(oxetan-3-yloxy)pyr...) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(CS(C)(=O)=O)nc3OC3COC3)nc12)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577564 (2-[[1-(Methylsulfonylmethyl)-3-(oxetan-3-yloxy)pyr...) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(CS(C)(=O)=O)nc3OC3COC3)nc12)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577557 (2-((1-methyl-3-(((2S,3R)-2-methyloxetan-3-yl)oxy)-...) Show SMILES C[C@@H]1OCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577568 (2-((3-(((S)-1-acetyl-2,2-dimethylazetidin-3-yl)oxy...) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3O[C@H]3CN(C(C)=O)C3(C)C)nc12)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577568 (2-((3-(((S)-1-acetyl-2,2-dimethylazetidin-3-yl)oxy...) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3O[C@H]3CN(C(C)=O)C3(C)C)nc12)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577557 (2-((1-methyl-3-(((2S,3R)-2-methyloxetan-3-yl)oxy)-...) Show SMILES C[C@@H]1OCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577570 (2-((4-(2-Hydroxypropan-2-yl)-2-(oxetan-3-yloxy)phe...) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3ccc(cc3OC3COC3)C(C)(C)O)nc12)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577570 (2-((4-(2-Hydroxypropan-2-yl)-2-(oxetan-3-yloxy)phe...) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3ccc(cc3OC3COC3)C(C)(C)O)nc12)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577567 (2-((3-(((R)-1 -Acetyl-2, 2-dimethylazetidin-3-yl)o...) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3O[C@@H]3CN(C(C)=O)C3(C)C)nc12)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577567 (2-((3-(((R)-1 -Acetyl-2, 2-dimethylazetidin-3-yl)o...) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3O[C@@H]3CN(C(C)=O)C3(C)C)nc12)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577556 (2-((1-Methyl-3-(((2R,3S)-2-methyloxetan-3-yl)oxy)-...) Show SMILES C[C@H]1OCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577556 (2-((1-Methyl-3-(((2R,3S)-2-methyloxetan-3-yl)oxy)-...) Show SMILES C[C@H]1OCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577556 (2-((1-Methyl-3-(((2R,3S)-2-methyloxetan-3-yl)oxy)-...) Show SMILES C[C@H]1OCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577553 (2-[[1 -methyl-3-[(3S,4R)-4-methyltetrahydrofuran-3...) Show SMILES C[C@@H]1COCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577555 (2-[[1 -[(1 S)-2,2-difluoro-1 -methyl-ethyl]-3-(oxe...) Show SMILES C[C@@H](C(F)F)n1cc(Nc2ncc3cc(C#N)n([C@H]4COC[C@@H]4C)c3n2)c(OC2COC2)n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577574 (2-((1 -(methyl-d3)-3-(((2S,3S)-2-methyloxetan-3-yl...) Show SMILES C[C@H]1OC[C@H]1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577587 (2-((1-((S)-1-Cyanoethyl)-3-isopropoxy-1 H-pyrazol-...) Show SMILES CO[C@H]1COC[C@H]1n1c(cc2cnc(Nc3cn(nc3OC(C)C)[C@H](C)C#N)nc12)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577558 (WO2022263472, Example 19 | WO2022263472, Example 8) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3OC3COC3)nc12)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577555 (2-[[1 -[(1 S)-2,2-difluoro-1 -methyl-ethyl]-3-(oxe...) Show SMILES C[C@@H](C(F)F)n1cc(Nc2ncc3cc(C#N)n([C@H]4COC[C@@H]4C)c3n2)c(OC2COC2)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577553 (2-[[1 -methyl-3-[(3S,4R)-4-methyltetrahydrofuran-3...) Show SMILES C[C@@H]1COCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577559 (2-[[1-[2-Hydroxy-1-methyl-ethyl]-3-(oxetan-3-yloxy...) Show SMILES CC(CO)n1cc(Nc2ncc3cc(C#N)n([C@H]4COC[C@@H]4C)c3n2)c(OC2COC2)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577552 (2-[[1-Methyl-3-[(3R,4S)-4-methyltetrahydrofuran-3-...) Show SMILES C[C@H]1COCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577552 (2-[[1-Methyl-3-[(3R,4S)-4-methyltetrahydrofuran-3-...) Show SMILES C[C@H]1COCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577556 (2-((1-Methyl-3-(((2R,3S)-2-methyloxetan-3-yl)oxy)-...) Show SMILES C[C@H]1OCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577559 (2-[[1-[2-Hydroxy-1-methyl-ethyl]-3-(oxetan-3-yloxy...) Show SMILES CC(CO)n1cc(Nc2ncc3cc(C#N)n([C@H]4COC[C@@H]4C)c3n2)c(OC2COC2)n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577558 (WO2022263472, Example 19 | WO2022263472, Example 8) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3OC3COC3)nc12)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577558 (WO2022263472, Example 19 | WO2022263472, Example 8) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3OC3COC3)nc12)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577582 ((R)-2-((1-Methyl-3-(oxetan-3-yloxy)-1 H-pyrazol-4-...) Show SMILES CC(C)Oc1nn(cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@H]3C)c2n1)[C@@H](C)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description LRRK2(human) is incubated with 50 mM HEPES pH 8.0, 0.2 mM EDTA, 0.01 %Brij-35, 1% (w/v) BSA, 5 mM DTT, 250 Mm RLGRDKYKTLRQIRQ, 10 mM Magnesium aceta...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577551 (2-[[3-(1-acetylazetidin-3-yl)oxy-1-methyl-pyrazol-...) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3OC3CN(C3)C(C)=O)nc12)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577574 (2-((1 -(methyl-d3)-3-(((2S,3S)-2-methyloxetan-3-yl...) Show SMILES C[C@H]1OC[C@H]1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577562 (2-[[3-[(3R,4R)-4-Methoxytetrahydrofuran-3-yl]oxy-1...) Show SMILES CO[C@H]1COC[C@@H]1ON(c1cnn(C)c1)c1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577558 (WO2022263472, Example 19 | WO2022263472, Example 8) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3OC3COC3)nc12)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577551 (2-[[3-(1-acetylazetidin-3-yl)oxy-1-methyl-pyrazol-...) Show SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3OC3CN(C3)C(C)=O)nc12)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577599 (WO2022263472, Example 80) Show SMILES Cn1cc(Nc2ncc3cc(C#N)n(C4CCOCC4)c3n2)c(OC2COC2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577557 (2-((1-methyl-3-(((2S,3R)-2-methyloxetan-3-yl)oxy)-...) Show SMILES C[C@@H]1OCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577557 (2-((1-methyl-3-(((2S,3R)-2-methyloxetan-3-yl)oxy)-...) Show SMILES C[C@@H]1OCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577581 (2-((1-((S)-1-cyanoethyl)-3-isopropoxy-1H-pyrazol-4...) Show SMILES CC(C)Oc1nn(cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@H]3C)c2n1)[C@H](C)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description LRRK2(human) is incubated with 50 mM HEPES pH 8.0, 0.2 mM EDTA, 0.01 %Brij-35, 1% (w/v) BSA, 5 mM DTT, 250 Mm RLGRDKYKTLRQIRQ, 10 mM Magnesium aceta...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577587 (2-((1-((S)-1-Cyanoethyl)-3-isopropoxy-1 H-pyrazol-...) Show SMILES CO[C@H]1COC[C@H]1n1c(cc2cnc(Nc3cn(nc3OC(C)C)[C@H](C)C#N)nc12)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577573 (2-((1-(Methyl-d3)-3-(((2R,3R)-2-methyloxetan-3-yl)...) Show SMILES C[C@@H]1OC[C@@H]1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577562 (2-[[3-[(3R,4R)-4-Methoxytetrahydrofuran-3-yl]oxy-1...) Show SMILES CO[C@H]1COC[C@@H]1ON(c1cnn(C)c1)c1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577563 (2-[[3-[(3S,4S)-4-methoxytetrahydrofuran-3-yl]oxy-1...) Show SMILES CO[C@@H]1COC[C@H]1ON(c1cnn(C)c1)c1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577599 (WO2022263472, Example 80) Show SMILES Cn1cc(Nc2ncc3cc(C#N)n(C4CCOCC4)c3n2)c(OC2COC2)n1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577573 (2-((1-(Methyl-d3)-3-(((2R,3R)-2-methyloxetan-3-yl)...) Show SMILES C[C@@H]1OC[C@@H]1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair

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