Compile Data Set for Download or QSAR

Found 420 hits with Last Name = 'urabe' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450193 (US10703755, Example 393 | US10703755, Example 403) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)[C@H]3CN4CCC3CC4)c2n1 |r,wD:25.26,(-6.37,-13.42,;-5.04,-14.19,;-3.71,-13.42,;-3.71,-11.88,;-2.37,-11.11,;-2.37,-9.57,;-1.04,-11.88,;.43,-11.41,;1.33,-12.65,;2.87,-12.65,;3.64,-13.98,;5.18,-13.98,;5.95,-12.65,;5.18,-11.32,;5.95,-9.98,;3.64,-11.32,;.43,-13.9,;.82,-15.38,;2.31,-15.78,;3.4,-14.69,;4.89,-15.09,;5.29,-16.58,;4.2,-17.67,;2.71,-17.27,;1.62,-18.36,;6.77,-16.98,;7.17,-18.47,;8.66,-18.87,;9.75,-17.78,;9.35,-16.29,;7.86,-15.89,;7.86,-17.43,;8.66,-17.33,;-1.04,-13.42,;-2.37,-14.19,)| Show InChI InChI=1S/C26H26F2N6O/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)19-9-20(27)12-29-11-19)13-18-4-3-17(10-22(18)28)21-14-33-7-5-16(21)6-8-33/h3-4,9-12,16,21H,5-8,13-14H2,1-2H3/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450104 (US10703755, Example 285) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@@H]4C[C@@H]5CC[C@H](C4)N5C)cc3F)c2n1 |r,THB:31:30:24.29.23:27.26| Show InChI InChI=1S/C27H28F2N6O2/c1-15-24-26(33-27(31-15)36-3)35(25(32-24)17-8-18(28)13-30-12-17)14-16-4-7-21(11-23(16)29)37-22-9-19-5-6-20(10-22)34(19)2/h4,7-8,11-13,19-20,22H,5-6,9-10,14H2,1-3H3/t19-,20+,22+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450060 (9-{4-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]benzyl}-8-(...) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)[C@H]3CN4CCC3CC4)c2n1 |r,wD:24.25,(-6.22,-13.2,;-5.04,-14.19,;-3.71,-13.42,;-3.71,-11.88,;-2.37,-11.11,;-2.37,-9.57,;-1.04,-11.88,;.43,-11.41,;1.33,-12.65,;2.87,-12.65,;3.64,-13.98,;5.18,-13.98,;5.95,-12.65,;5.18,-11.32,;5.95,-9.98,;3.64,-11.32,;.43,-13.9,;.82,-15.38,;2.31,-15.78,;2.71,-17.27,;4.2,-17.67,;5.29,-16.58,;4.89,-15.09,;3.4,-14.69,;6.77,-16.98,;7.17,-18.47,;8.66,-18.87,;9.75,-17.78,;9.35,-16.29,;7.86,-15.89,;7.86,-17.43,;8.66,-17.33,;-1.04,-13.42,;-2.37,-14.19,)| Show InChI InChI=1S/C26H27FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)20-11-21(27)13-28-12-20)14-17-3-5-18(6-4-17)22-15-32-9-7-19(22)8-10-32/h3-6,11-13,19,22H,7-10,14-15H2,1-2H3/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450099 (US10703755, Example 280) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@@H]5C[C@H]4CN5C)cc3F)c2n1 |r| Show InChI InChI=1S/C26H27F2N7O/c1-15-23-25(32-26(30-15)36-3)35(24(31-23)18-7-19(27)10-29-9-18)12-17-5-4-16(6-22(17)28)11-34-14-20-8-21(34)13-33(20)2/h4-7,9-10,20-21H,8,11-14H2,1-3H3/t20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450103 (US10703755, Example 284) Show SMILES CCN1CCC(CC1)c1ccc(Cn2c(nc3c(C)nc(OC)nc23)-c2cncc(F)c2)c(F)c1 Show InChI InChI=1S/C26H28F2N6O/c1-4-33-9-7-17(8-10-33)18-5-6-19(22(28)12-18)15-34-24(20-11-21(27)14-29-13-20)31-23-16(2)30-26(35-3)32-25(23)34/h5-6,11-14,17H,4,7-10,15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450055 (US10703755, Example 172) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1 |(-8.05,2.46,;-8.57,1.02,;-7.39,.03,;-6.06,.8,;-6.06,2.34,;-4.73,3.11,;-4.73,4.65,;-3.39,2.34,;-1.93,2.81,;-1.02,1.57,;.52,1.57,;1.29,.23,;2.83,.23,;3.6,1.57,;2.83,2.9,;3.6,4.23,;1.29,2.9,;-1.93,.32,;-1.53,-1.17,;-.04,-1.57,;1.05,-.48,;2.53,-.87,;2.93,-2.36,;1.84,-3.45,;.36,-3.05,;-.73,-4.14,;4.42,-2.76,;4.82,-4.25,;6.31,-4.65,;7.39,-3.56,;7,-2.07,;5.51,-1.67,;5.51,-3.21,;6.31,-3.11,;-3.39,.8,;-4.73,.03,)| Show InChI InChI=1S/C27H28F2N6O/c1-3-36-27-31-16(2)24-26(33-27)35(25(32-24)20-10-21(28)13-30-12-20)14-19-5-4-18(11-23(19)29)22-15-34-8-6-17(22)7-9-34/h4-5,10-13,17,22H,3,6-9,14-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450121 (US10703755, Example 304) Show SMILES COc1nc(C)c2nc(-c3cnccc3C)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1 |(-8.57,1.02,;-7.39,.03,;-6.06,.8,;-6.06,2.34,;-4.73,3.11,;-4.73,4.65,;-3.39,2.34,;-1.93,2.81,;-1.02,1.57,;.52,1.57,;1.29,.23,;2.83,.23,;3.6,1.57,;2.83,2.9,;1.26,2.95,;.49,4.28,;-1.93,.32,;-1.53,-1.17,;-.04,-1.57,;1.05,-.48,;2.53,-.87,;2.93,-2.36,;1.84,-3.45,;.36,-3.05,;-.73,-4.14,;4.42,-2.76,;4.82,-4.25,;6.31,-4.65,;7.39,-3.56,;7,-2.07,;5.51,-1.67,;5.51,-3.21,;6.31,-3.11,;-3.39,.8,;-4.73,.03,)| Show InChI InChI=1S/C27H29FN6O/c1-16-6-9-29-13-21(16)25-31-24-17(2)30-27(35-3)32-26(24)34(25)14-20-5-4-19(12-23(20)28)22-15-33-10-7-18(22)8-11-33/h4-6,9,12-13,18,22H,7-8,10-11,14-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450122 (US10703755, Example 305) Show SMILES COc1nc(C)c2nc(-c3cncc(C)c3)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1 |(-8.57,1.02,;-7.39,.03,;-6.06,.8,;-6.06,2.34,;-4.73,3.11,;-4.73,4.65,;-3.39,2.34,;-1.93,2.81,;-1.02,1.57,;.52,1.57,;1.29,.23,;2.83,.23,;3.6,1.57,;2.84,3,;3.59,4.34,;1.29,2.9,;-1.93,.32,;-1.53,-1.17,;-.04,-1.57,;1.05,-.48,;2.53,-.87,;2.93,-2.36,;1.84,-3.45,;.36,-3.05,;-.73,-4.14,;4.42,-2.76,;4.82,-4.25,;6.31,-4.65,;7.39,-3.56,;7,-2.07,;5.51,-1.67,;5.51,-3.21,;6.31,-3.11,;-3.39,.8,;-4.73,.03,)| Show InChI InChI=1S/C27H29FN6O/c1-16-10-21(13-29-12-16)25-31-24-17(2)30-27(35-3)32-26(24)34(25)14-20-5-4-19(11-23(20)28)22-15-33-8-6-18(22)7-9-33/h4-5,10-13,18,22H,6-9,14-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM449992 (US10703755, Example 110) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@H]5C[C@@H]4CN5C)cc3)c2n1 |r| Show InChI InChI=1S/C27H30FN7O/c1-4-36-27-30-17(2)24-26(32-27)35(25(31-24)20-9-21(28)12-29-11-20)14-19-7-5-18(6-8-19)13-34-16-22-10-23(34)15-33(22)3/h5-9,11-12,22-23H,4,10,13-16H2,1-3H3/t22-,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450208 (US10703755, Example 412) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@@H]4CN5CCC4CC5)cc3F)c2n1 |r,wD:23.23,(-8.92,.76,;-7.74,-.23,;-6.41,.54,;-6.41,2.08,;-5.08,2.85,;-5.08,4.39,;-3.74,2.08,;-2.28,2.56,;-1.37,1.31,;.17,1.31,;.94,-.02,;2.48,-.02,;3.25,1.31,;2.48,2.65,;3.25,3.98,;.94,2.65,;-2.28,.07,;-1.88,-1.42,;-.39,-1.82,;.7,-.73,;2.18,-1.13,;2.58,-2.62,;4.07,-3.01,;5.16,-1.92,;4.78,-.43,;5.88,.64,;7.36,.23,;7.74,-1.26,;6.64,-2.34,;6.66,-.8,;5.79,-.79,;1.49,-3.7,;.01,-3.31,;-1.08,-4.39,;-3.74,.54,;-5.08,-.23,)| Show InChI InChI=1S/C26H26F2N6O2/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)18-9-19(27)12-29-11-18)13-17-3-4-20(10-21(17)28)36-22-14-33-7-5-16(22)6-8-33/h3-4,9-12,16,22H,5-8,13-14H2,1-2H3/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450195 (US10703755, Example 395) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc([C@H]4CN5CCC4CC5)c(c3)C#N)c2n1 |r,wD:23.23,(-7.56,-13.3,;-6.22,-12.53,;-4.89,-13.3,;-3.56,-12.53,;-3.56,-10.99,;-2.22,-10.22,;-2.22,-8.68,;-.89,-10.99,;.57,-10.52,;1.48,-11.76,;3.02,-11.76,;3.79,-13.1,;5.33,-13.1,;6.1,-11.76,;5.33,-10.43,;6.1,-9.09,;3.79,-10.43,;.57,-13.01,;.97,-14.5,;2.46,-14.89,;3.55,-13.8,;5.04,-14.2,;5.44,-15.69,;6.92,-16.09,;7.32,-17.58,;8.81,-17.98,;9.9,-16.89,;9.5,-15.4,;8.01,-15,;8.01,-16.54,;8.81,-16.44,;4.36,-16.83,;2.86,-16.38,;4.76,-18.32,;5.16,-19.81,;-.89,-12.53,;-2.22,-13.3,)| Show InChI InChI=1S/C28H28FN7O/c1-3-37-28-32-17(2)25-27(34-28)36(26(33-25)21-11-22(29)14-31-13-21)15-18-4-5-23(20(10-18)12-30)24-16-35-8-6-19(24)7-9-35/h4-5,10-11,13-14,19,24H,3,6-9,15-16H2,1-2H3/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450201 (US10703755, Example 401) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc([C@H]4CN5CCC4CC5)c(c3)C#N)c2n1 |r,wD:22.22,(-6.37,-12.53,;-5.04,-13.3,;-3.71,-12.53,;-3.71,-10.99,;-2.37,-10.22,;-2.37,-8.68,;-1.04,-10.99,;.43,-10.52,;1.33,-11.76,;2.87,-11.76,;3.64,-13.1,;5.18,-13.1,;5.95,-11.76,;5.18,-10.43,;5.95,-9.09,;3.64,-10.43,;.43,-13.01,;.82,-14.5,;2.31,-14.89,;3.4,-13.8,;4.89,-14.2,;5.29,-15.69,;6.77,-16.09,;7.17,-17.58,;8.66,-17.98,;9.75,-16.89,;9.35,-15.4,;7.86,-15,;7.86,-16.54,;8.66,-16.44,;4.21,-16.83,;2.71,-16.38,;4.61,-18.32,;5.01,-19.81,;-1.04,-12.53,;-2.37,-13.3,)| Show InChI InChI=1S/C27H26FN7O/c1-16-24-26(33-27(31-16)36-2)35(25(32-24)20-10-21(28)13-30-12-20)14-17-3-4-22(19(9-17)11-29)23-15-34-7-5-18(23)6-8-34/h3-4,9-10,12-13,18,23H,5-8,14-15H2,1-2H3/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450120 (US10703755, Example 303) Show SMILES COc1nc(C)c2nc(-c3cccnc3)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1 |(-8.57,1.02,;-7.39,.03,;-6.06,.8,;-6.06,2.34,;-4.73,3.11,;-4.73,4.65,;-3.39,2.34,;-1.93,2.81,;-1.02,1.57,;.52,1.57,;1.29,2.9,;2.83,2.9,;3.6,1.57,;2.83,.23,;1.29,.23,;-1.93,.32,;-1.53,-1.17,;-.04,-1.57,;1.05,-.48,;2.53,-.87,;2.93,-2.36,;1.84,-3.45,;.36,-3.05,;-.73,-4.14,;4.42,-2.76,;4.82,-4.25,;6.31,-4.65,;7.39,-3.56,;7,-2.07,;5.51,-1.67,;5.51,-3.21,;6.31,-3.11,;-3.39,.8,;-4.73,.03,)| Show InChI InChI=1S/C26H27FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)19-4-3-9-28-13-19)14-20-6-5-18(12-22(20)27)21-15-32-10-7-17(21)8-11-32/h3-6,9,12-13,17,21H,7-8,10-11,14-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450014 (US10703755, Example 131) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@@H]5C[C@H]4CN5CC)cc3)c2n1 |r| Show InChI InChI=1S/C28H32FN7O/c1-4-34-16-24-11-23(34)17-35(24)14-19-6-8-20(9-7-19)15-36-26(21-10-22(29)13-30-12-21)32-25-18(3)31-28(37-5-2)33-27(25)36/h6-10,12-13,23-24H,4-5,11,14-17H2,1-3H3/t23-,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450052 (US10703755, Example 169) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)C3CN4CCC3CC4)c2n1 |(-8.05,2.46,;-8.57,1.02,;-7.39,.03,;-6.06,.8,;-6.06,2.34,;-4.73,3.11,;-4.73,4.65,;-3.39,2.34,;-1.93,2.81,;-1.02,1.57,;.52,1.57,;1.29,.23,;2.83,.23,;3.6,1.57,;2.83,2.9,;3.6,4.23,;1.29,2.9,;-1.93,.32,;-1.53,-1.17,;-.04,-1.57,;.36,-3.05,;1.84,-3.45,;2.93,-2.36,;2.53,-.87,;1.05,-.48,;4.42,-2.76,;4.82,-4.25,;6.31,-4.65,;7.39,-3.56,;7,-2.07,;5.51,-1.67,;5.51,-3.21,;6.31,-3.11,;-3.39,.8,;-4.73,.03,)| Show InChI InChI=1S/C27H29FN6O/c1-3-35-27-30-17(2)24-26(32-27)34(25(31-24)21-12-22(28)14-29-13-21)15-18-4-6-19(7-5-18)23-16-33-10-8-20(23)9-11-33/h4-7,12-14,20,23H,3,8-11,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450133 (US10703755, Example 316) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(C4CN5CCC4CC5)c(c3)C#N)c2n1 |(-8.05,3.35,;-8.57,1.91,;-7.39,.92,;-6.06,1.69,;-6.06,3.23,;-4.73,4,;-4.73,5.54,;-3.39,3.23,;-1.93,3.7,;-1.02,2.46,;.52,2.46,;1.29,1.12,;2.83,1.12,;3.6,2.46,;2.83,3.79,;3.6,5.12,;1.29,3.79,;-1.93,1.21,;-1.53,-.28,;-.04,-.68,;1.05,.41,;2.53,.01,;2.93,-1.47,;4.42,-1.87,;4.82,-3.36,;6.31,-3.76,;7.39,-2.67,;7,-1.18,;5.51,-.78,;5.29,-2.27,;6.52,-2.27,;1.86,-2.61,;.36,-2.16,;2.26,-4.1,;2.65,-5.59,;-3.39,1.69,;-4.73,.92,)| Show InChI InChI=1S/C28H28FN7O/c1-3-37-28-32-17(2)25-27(34-28)36(26(33-25)21-11-22(29)14-31-13-21)15-18-4-5-23(20(10-18)12-30)24-16-35-8-6-19(24)7-9-35/h4-5,10-11,13-14,19,24H,3,6-9,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450179 (US10703755, Example 377) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(C4CN5CCC4CC5)c(F)c3)c2n1 |(-8.57,1.16,;-7.39,.17,;-6.06,.94,;-6.06,2.48,;-4.73,3.25,;-4.73,4.79,;-3.39,2.48,;-1.93,2.96,;-1.02,1.71,;.52,1.71,;1.29,.38,;2.83,.38,;3.6,1.71,;2.83,3.05,;3.6,4.38,;1.29,3.05,;-1.93,.47,;-1.53,-1.02,;-.04,-1.42,;1.05,-.33,;2.53,-.73,;2.93,-2.22,;4.42,-2.62,;4.82,-4.1,;6.31,-4.5,;7.39,-3.41,;7,-1.92,;5.51,-1.53,;5.51,-3.07,;6.38,-3.06,;1.84,-3.31,;2.24,-4.79,;.36,-2.91,;-3.39,.94,;-4.73,.17,)| Show InChI InChI=1S/C26H26F2N6O/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)18-10-19(27)12-29-11-18)13-16-3-4-20(22(28)9-16)21-14-33-7-5-17(21)6-8-33/h3-4,9-12,17,21H,5-8,13-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450135 (US10703755, Example 318) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(C4CN5CCC4CC5)c(c3)C#N)c2n1 |(-8.57,1.91,;-7.39,.92,;-6.06,1.69,;-6.06,3.23,;-4.73,4,;-4.73,5.54,;-3.39,3.23,;-1.93,3.7,;-1.02,2.46,;.52,2.46,;1.29,1.12,;2.83,1.12,;3.6,2.46,;2.83,3.79,;3.6,5.12,;1.29,3.79,;-1.93,1.21,;-1.53,-.28,;-.04,-.68,;1.05,.41,;2.53,.01,;2.93,-1.47,;4.42,-1.87,;4.82,-3.36,;6.31,-3.76,;7.39,-2.67,;7,-1.18,;5.51,-.78,;5.29,-2.27,;6.52,-2.27,;1.86,-2.61,;.36,-2.16,;2.26,-4.1,;2.65,-5.59,;-3.39,1.69,;-4.73,.92,)| Show InChI InChI=1S/C27H26FN7O/c1-16-24-26(33-27(31-16)36-2)35(25(32-24)20-10-21(28)13-30-12-20)14-17-3-4-22(19(9-17)11-29)23-15-34-7-5-18(23)6-8-34/h3-4,9-10,12-13,18,23H,5-8,14-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450131 (US10703755, Example 314) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1 |(-8.57,1.02,;-7.39,.03,;-6.06,.8,;-6.06,2.34,;-4.73,3.11,;-4.73,4.65,;-3.39,2.34,;-1.93,2.81,;-1.02,1.57,;.52,1.57,;1.29,.23,;2.83,.23,;3.6,1.57,;2.83,2.9,;3.6,4.23,;1.29,2.9,;-1.93,.32,;-1.53,-1.17,;-.04,-1.57,;1.05,-.48,;2.53,-.87,;2.93,-2.36,;1.84,-3.45,;.36,-3.05,;-.73,-4.14,;4.42,-2.76,;4.82,-4.25,;6.31,-4.65,;7.39,-3.56,;7,-2.07,;5.51,-1.67,;5.51,-3.21,;6.31,-3.11,;-3.39,.8,;-4.73,.03,)| Show InChI InChI=1S/C26H26F2N6O/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)19-9-20(27)12-29-11-19)13-18-4-3-17(10-22(18)28)21-14-33-7-5-16(21)6-8-33/h3-4,9-12,16,21H,5-8,13-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450130 (US10703755, Example 313) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4CC5CC4CN5C)cc3F)c2n1 Show InChI InChI=1S/C27H29F2N7O/c1-4-37-27-31-16(2)24-26(33-27)36(25(32-24)19-8-20(28)11-30-10-19)13-18-6-5-17(7-23(18)29)12-35-15-21-9-22(35)14-34(21)3/h5-8,10-11,21-22H,4,9,12-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450223 (US10703755, Example 431) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)C3CCNCC3)c2n1 Show InChI InChI=1S/C24H24F2N6O/c1-14-21-23(31-24(29-14)33-2)32(22(30-21)18-9-19(25)12-28-11-18)13-17-4-3-16(10-20(17)26)15-5-7-27-8-6-15/h3-4,9-12,15,27H,5-8,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450101 (US10703755, Example 282) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)C3CCN(C)CC3)c2n1 Show InChI InChI=1S/C25H26F2N6O/c1-15-22-24(31-25(29-15)34-3)33(23(30-22)19-10-20(26)13-28-12-19)14-18-5-4-17(11-21(18)27)16-6-8-32(2)9-7-16/h4-5,10-13,16H,6-9,14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450225 (US10703755, Example 433) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@@H]4C[C@@H]5CC[C@H](C4)N5)cc3F)c2n1 |r| Show InChI InChI=1S/C26H26F2N6O2/c1-14-23-25(33-26(30-14)35-2)34(24(32-23)16-7-17(27)12-29-11-16)13-15-3-6-20(10-22(15)28)36-21-8-18-4-5-19(9-21)31-18/h3,6-7,10-12,18-19,21,31H,4-5,8-9,13H2,1-2H3/t18-,19+,21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450209 (US10703755, Example 413) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@H]4CN5CCC4CC5)cc3F)c2n1 |r,wU:23.23,(-8.92,.76,;-7.74,-.23,;-6.41,.54,;-6.41,2.08,;-5.08,2.85,;-5.08,4.39,;-3.74,2.08,;-2.28,2.56,;-1.37,1.31,;.17,1.31,;.94,-.02,;2.48,-.02,;3.25,1.31,;2.48,2.65,;3.25,3.98,;.94,2.65,;-2.28,.07,;-1.88,-1.42,;-.39,-1.82,;.7,-.73,;2.18,-1.13,;2.58,-2.62,;4.07,-3.01,;5.16,-1.92,;4.78,-.43,;5.88,.64,;7.36,.23,;7.74,-1.26,;6.64,-2.34,;6.66,-.8,;5.79,-.79,;1.49,-3.7,;.01,-3.31,;-1.08,-4.39,;-3.74,.54,;-5.08,-.23,)| Show InChI InChI=1S/C26H26F2N6O2/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)18-9-19(27)12-29-11-18)13-17-3-4-20(10-21(17)28)36-22-14-33-7-5-16(22)6-8-33/h3-4,9-12,16,22H,5-8,13-14H2,1-2H3/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450060 (9-{4-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]benzyl}-8-(...) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)[C@H]3CN4CCC3CC4)c2n1 |r,wD:24.25,(-6.22,-13.2,;-5.04,-14.19,;-3.71,-13.42,;-3.71,-11.88,;-2.37,-11.11,;-2.37,-9.57,;-1.04,-11.88,;.43,-11.41,;1.33,-12.65,;2.87,-12.65,;3.64,-13.98,;5.18,-13.98,;5.95,-12.65,;5.18,-11.32,;5.95,-9.98,;3.64,-11.32,;.43,-13.9,;.82,-15.38,;2.31,-15.78,;2.71,-17.27,;4.2,-17.67,;5.29,-16.58,;4.89,-15.09,;3.4,-14.69,;6.77,-16.98,;7.17,-18.47,;8.66,-18.87,;9.75,-17.78,;9.35,-16.29,;7.86,-15.89,;7.86,-17.43,;8.66,-17.33,;-1.04,-13.42,;-2.37,-14.19,)| Show InChI InChI=1S/C26H27FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)20-11-21(27)13-28-12-20)14-17-3-5-18(6-4-17)22-15-32-9-7-19(22)8-10-32/h3-6,11-13,19,22H,7-10,14-15H2,1-2H3/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450046 (9-{[1-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-1H-pyraz...) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3cnn(CC4CN5CCC4CC5)c3)c2n1 |(-6.27,-3.01,;-6.79,-4.46,;-5.61,-5.45,;-4.28,-4.68,;-4.28,-3.14,;-2.95,-2.37,;-2.95,-.83,;-1.61,-3.14,;-.15,-2.66,;.76,-3.91,;2.3,-3.91,;3.07,-5.24,;4.61,-5.24,;5.38,-3.91,;4.61,-2.57,;5.38,-1.24,;3.07,-2.57,;-.15,-5.15,;.62,-6.49,;1.96,-7.26,;2.43,-8.72,;3.97,-8.72,;4.45,-7.26,;5.78,-6.49,;7.11,-7.26,;8.45,-6.49,;9.78,-7.26,;9.78,-8.8,;8.45,-9.57,;7.11,-8.8,;8.65,-8.8,;8.24,-7.26,;3.2,-6.35,;-1.61,-4.68,;-2.95,-5.45,)| Show InChI InChI=1S/C25H29FN8O/c1-3-35-25-29-16(2)22-24(31-25)34(23(30-22)19-8-21(26)11-27-10-19)13-17-9-28-33(12-17)15-20-14-32-6-4-18(20)5-7-32/h8-12,18,20H,3-7,13-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM449991 (US10703755, Example 109) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@@H]5C[C@H]4CN5C)cc3)c2n1 |r| Show InChI InChI=1S/C27H30FN7O/c1-4-36-27-30-17(2)24-26(32-27)35(25(31-24)20-9-21(28)12-29-11-20)14-19-7-5-18(6-8-19)13-34-16-22-10-23(34)15-33(22)3/h5-9,11-12,22-23H,4,10,13-16H2,1-3H3/t22-,23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450128 (US10703755, Example 311) Show SMILES CCOc1nc(C)c2nc(-c3cncc(c3)C#N)n(Cc3ccc(CN4CC5CC4CN5C)cc3F)c2n1 Show InChI InChI=1S/C28H29FN8O/c1-4-38-28-32-17(2)25-27(34-28)37(26(33-25)21-7-19(10-30)11-31-12-21)14-20-6-5-18(8-24(20)29)13-36-16-22-9-23(36)15-35(22)3/h5-8,11-12,22-23H,4,9,13-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450167 (US10703755, Example 364) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3cccc(c3)C3=CN4CCC3CC4)c2n1 |t:26,(-6.92,2.66,;-5.74,1.67,;-4.4,2.44,;-4.4,3.98,;-3.07,4.75,;-3.07,6.29,;-1.74,3.98,;-.27,4.46,;.63,3.21,;2.17,3.21,;2.94,1.88,;4.48,1.88,;5.25,3.21,;4.48,4.54,;5.25,5.88,;2.94,4.54,;-.27,1.96,;.13,.48,;1.62,.08,;2.7,1.17,;4.19,.77,;4.59,-.72,;3.5,-1.81,;2.01,-1.41,;3.9,-3.3,;2.78,-4.36,;3.14,-5.85,;3.83,-4.59,;4.57,-5.05,;5.38,-3.73,;5.74,-5.23,;4.62,-6.29,;-1.74,2.44,;-3.07,1.67,)| Show InChI InChI=1S/C26H25FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)20-11-21(27)13-28-12-20)14-17-4-3-5-19(10-17)22-15-32-8-6-18(22)7-9-32/h3-5,10-13,15,18H,6-9,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450059 (US10703755, Example 176) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)[C@H]3CN4CCC3CC4)c2n1 |r,wD:25.26,(-7.56,-14.19,;-6.22,-13.42,;-4.89,-14.19,;-3.56,-13.42,;-3.56,-11.88,;-2.22,-11.11,;-2.22,-9.57,;-.89,-11.88,;.57,-11.41,;1.48,-12.65,;3.02,-12.65,;3.79,-13.98,;5.33,-13.98,;6.1,-12.65,;5.33,-11.32,;6.1,-9.98,;3.79,-11.32,;.57,-13.9,;.97,-15.38,;2.46,-15.78,;2.86,-17.27,;4.35,-17.67,;5.44,-16.58,;5.04,-15.09,;3.55,-14.69,;6.92,-16.98,;7.32,-18.47,;8.81,-18.87,;9.9,-17.78,;9.5,-16.29,;8.01,-15.89,;8.01,-17.43,;8.81,-17.33,;-.89,-13.42,;-2.22,-14.19,)| Show InChI InChI=1S/C27H29FN6O/c1-3-35-27-30-17(2)24-26(32-27)34(25(31-24)21-12-22(28)14-29-13-21)15-18-4-6-19(7-5-18)23-16-33-10-8-20(23)9-11-33/h4-7,12-14,20,23H,3,8-11,15-16H2,1-2H3/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450174 (US10703755, Example 372) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3OC)C3CN4CCC3CC4)c2n1 |(-8.05,2.46,;-8.57,1.02,;-7.39,.03,;-6.06,.8,;-6.06,2.34,;-4.73,3.11,;-4.73,4.65,;-3.39,2.34,;-1.93,2.81,;-1.02,1.57,;.52,1.57,;1.29,.23,;2.83,.23,;3.6,1.57,;2.83,2.9,;3.6,4.23,;1.29,2.9,;-1.93,.32,;-1.53,-1.17,;-.04,-1.57,;1.05,-.48,;2.53,-.87,;2.93,-2.36,;1.84,-3.45,;.36,-3.05,;-.73,-4.14,;-2.13,-3.49,;4.42,-2.76,;4.82,-4.25,;6.31,-4.65,;7.39,-3.56,;7,-2.07,;5.51,-1.67,;5.51,-3.21,;6.38,-3.21,;-3.39,.8,;-4.73,.03,)| Show InChI InChI=1S/C28H31FN6O2/c1-4-37-28-31-17(2)25-27(33-28)35(26(32-25)21-11-22(29)14-30-13-21)15-20-6-5-19(12-24(20)36-3)23-16-34-9-7-18(23)8-10-34/h5-6,11-14,18,23H,4,7-10,15-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450151 (US10703755, Example 344) Show SMILES COc1nc(C)c2nc(-c3cccc(c3)C#N)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1 |(-8.57,.56,;-7.39,-.43,;-6.06,.34,;-6.06,1.88,;-4.73,2.65,;-4.73,4.19,;-3.39,1.88,;-1.93,2.35,;-1.02,1.11,;.52,1.11,;1.29,-.23,;2.83,-.23,;3.6,1.11,;2.84,2.54,;1.29,2.44,;3.59,3.88,;4.34,5.23,;-1.93,-.14,;-1.53,-1.63,;-.04,-2.03,;1.05,-.94,;2.53,-1.34,;2.93,-2.82,;1.84,-3.91,;.36,-3.51,;-.73,-4.6,;4.42,-3.22,;4.82,-4.71,;6.31,-5.11,;7.39,-4.02,;7,-2.53,;5.51,-2.13,;5.51,-3.67,;6.31,-3.57,;-3.39,.34,;-4.73,-.43,)| Show InChI InChI=1S/C28H27FN6O/c1-17-25-27(33-28(31-17)36-2)35(26(32-25)21-5-3-4-18(12-21)14-30)15-22-7-6-20(13-24(22)29)23-16-34-10-8-19(23)9-11-34/h3-7,12-13,19,23H,8-11,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450114 (US10703755, Example 295) Show SMILES COc1nc(C)c2nc(-c3cncc(c3)C#N)n(Cc3ccc(OC4CC5CCC(C4)N5C)cc3F)c2n1 Show InChI InChI=1S/C28H28FN7O2/c1-16-25-27(34-28(32-16)37-3)36(26(33-25)19-8-17(12-30)13-31-14-19)15-18-4-7-22(11-24(18)29)38-23-9-20-5-6-21(10-23)35(20)2/h4,7-8,11,13-14,20-21,23H,5-6,9-10,15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450136 (US10703755, Example 322) Show SMILES COc1nc(C)c2nc(-c3cncc(c3)C#N)n(Cc3ccc(OC4CN5CCC4CC5)cc3F)c2n1 |(-8.92,.3,;-7.74,-.69,;-6.41,.08,;-6.41,1.62,;-5.07,2.39,;-5.07,3.93,;-3.74,1.62,;-2.27,2.1,;-1.37,.85,;.17,.85,;.94,-.48,;2.48,-.48,;3.25,.85,;2.55,2.25,;.94,2.19,;3.34,3.57,;4.12,4.9,;-2.27,-.39,;-1.88,-1.88,;-.39,-2.28,;.7,-1.19,;2.19,-1.59,;2.59,-3.08,;4.07,-3.47,;5.16,-2.39,;4.76,-.9,;5.85,.19,;7.34,-.21,;7.74,-1.69,;6.65,-2.78,;6.65,-1.24,;5.85,-1.35,;1.5,-4.16,;.01,-3.77,;-1.08,-4.85,;-3.74,.08,;-5.07,-.69,)| Show InChI InChI=1S/C27H26FN7O2/c1-16-24-26(33-27(31-16)36-2)35(25(32-24)20-9-17(11-29)12-30-13-20)14-19-3-4-21(10-22(19)28)37-23-15-34-7-5-18(23)6-8-34/h3-4,9-10,12-13,18,23H,5-8,14-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450187 (US10703755, Example 386) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3cccc(c3)C3CN4CCC3CC4)c2n1 |(-6.77,2.7,;-5.59,1.71,;-4.26,2.48,;-4.26,4.02,;-2.93,4.79,;-2.93,6.33,;-1.59,4.02,;-.13,4.49,;.78,3.25,;2.32,3.25,;3.09,1.91,;4.63,1.91,;5.4,3.25,;4.63,4.58,;5.4,5.91,;3.09,4.58,;-.13,2,;.27,.51,;1.76,.11,;2.85,1.2,;4.34,.8,;4.73,-.68,;3.64,-1.77,;2.16,-1.37,;4.04,-3.26,;2.79,-4.15,;2.94,-5.69,;4.34,-6.33,;5.59,-5.43,;5.44,-3.9,;4,-4.44,;4.31,-5.26,;-1.59,2.48,;-2.93,1.71,)| Show InChI InChI=1S/C26H27FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)20-11-21(27)13-28-12-20)14-17-4-3-5-19(10-17)22-15-32-8-6-18(22)7-9-32/h3-5,10-13,18,22H,6-9,14-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450192 (9-{4-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-2-fluorobe...) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)[C@@H]3CN4CCC3CC4)c2n1 |r,wU:25.26,(-6.37,-13.42,;-5.04,-14.19,;-3.71,-13.42,;-3.71,-11.88,;-2.37,-11.11,;-2.37,-9.57,;-1.04,-11.88,;.43,-11.41,;1.33,-12.65,;2.87,-12.65,;3.64,-13.98,;5.18,-13.98,;5.95,-12.65,;5.18,-11.32,;5.95,-9.98,;3.64,-11.32,;.43,-13.9,;.82,-15.38,;2.31,-15.78,;3.4,-14.69,;4.89,-15.09,;5.29,-16.58,;4.2,-17.67,;2.71,-17.27,;1.62,-18.36,;6.77,-16.98,;7.17,-18.47,;8.66,-18.87,;9.75,-17.78,;9.35,-16.29,;7.86,-15.89,;7.86,-17.43,;8.66,-17.33,;-1.04,-13.42,;-2.37,-14.19,)| Show InChI InChI=1S/C26H26F2N6O/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)19-9-20(27)12-29-11-19)13-18-4-3-17(10-22(18)28)21-14-33-7-5-16(21)6-8-33/h3-4,9-12,16,21H,5-8,13-14H2,1-2H3/t21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450016 (US10703755, Example 133) Show SMILES CCCN1C[C@@H]2C[C@H]1CN2Cc1ccc(Cn2c(nc3c(C)nc(OC)nc23)-c2cncc(F)c2)cc1 |r| Show InChI InChI=1S/C28H32FN7O/c1-4-9-34-16-24-11-23(34)17-35(24)14-19-5-7-20(8-6-19)15-36-26(21-10-22(29)13-30-12-21)32-25-18(2)31-28(37-3)33-27(25)36/h5-8,10,12-13,23-24H,4,9,11,14-17H2,1-3H3/t23-,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450210 (US10703755, Example 414) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@H]4CCN(C)C4)cc3F)c2n1 |r| Show InChI InChI=1S/C24H24F2N6O2/c1-14-21-23(30-24(28-14)33-3)32(22(29-21)16-8-17(25)11-27-10-16)12-15-4-5-18(9-20(15)26)34-19-6-7-31(2)13-19/h4-5,8-11,19H,6-7,12-13H2,1-3H3/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450211 (US10703755, Example 415) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@@H]4CCN(C)C4)cc3F)c2n1 |r| Show InChI InChI=1S/C24H24F2N6O2/c1-14-21-23(30-24(28-14)33-3)32(22(29-21)16-8-17(25)11-27-10-16)12-15-4-5-18(9-20(15)26)34-19-6-7-31(2)13-19/h4-5,8-11,19H,6-7,12-13H2,1-3H3/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450048 (9-[4-(1-Azabicyclo[2.2.2]oct-3-yl)benzyl]-8-(5-flu...) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)C3CN4CCC3CC4)c2n1 |(-6.59,-6.21,;-5.41,-7.2,;-4.08,-6.43,;-4.08,-4.89,;-2.74,-4.12,;-2.74,-2.58,;-1.41,-4.89,;.05,-4.41,;.96,-5.66,;2.5,-5.66,;3.27,-6.99,;4.81,-6.99,;5.58,-5.66,;4.81,-4.33,;5.58,-2.99,;3.27,-4.33,;.05,-6.91,;.82,-8.24,;2.31,-8.64,;3.4,-7.55,;4.89,-7.95,;5.29,-9.44,;4.2,-10.52,;2.71,-10.13,;6.77,-9.83,;7.17,-11.32,;8.66,-11.72,;9.75,-10.63,;9.35,-9.14,;7.86,-8.74,;7.86,-10.28,;8.66,-10.18,;-1.41,-6.43,;-2.74,-7.2,)| Show InChI InChI=1S/C26H27FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)20-11-21(27)13-28-12-20)14-17-3-5-18(6-4-17)22-15-32-9-7-19(22)8-10-32/h3-6,11-13,19,22H,7-10,14-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450031 (1-[4-(4-{[6-Amino-2-ethoxy-8-(5-fluoropyridin-3-yl...) Show SMILES CCOc1nc(N)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)C3CCN(CC3)C(=O)CN(C)C)c2n1 Show InChI InChI=1S/C28H33FN8O2/c1-4-39-28-33-25(30)24-27(34-28)37(26(32-24)21-13-22(29)15-31-14-21)16-18-5-7-19(8-6-18)20-9-11-36(12-10-20)23(38)17-35(2)3/h5-8,13-15,20H,4,9-12,16-17H2,1-3H3,(H2,30,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450229 (US10703755, Example 437) Show SMILES COc1nc(C)c2nc(-c3cccnc3)n(Cc3ccc(O[C@@H]4C[C@@H]5CC[C@H](C4)N5)cc3F)c2n1 |r| Show InChI InChI=1S/C26H27FN6O2/c1-15-23-25(32-26(29-15)34-2)33(24(31-23)16-4-3-9-28-13-16)14-17-5-8-20(12-22(17)27)35-21-10-18-6-7-19(11-21)30-18/h3-5,8-9,12-13,18-19,21,30H,6-7,10-11,14H2,1-2H3/t18-,19+,21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450110 (US10703755, Example 291) Show SMILES CCN1CCC(C1)c1ccc(Cn2c(nc3c(C)nc(OC)nc23)-c2cncc(F)c2)c(F)c1 Show InChI InChI=1S/C25H26F2N6O/c1-4-32-8-7-17(13-32)16-5-6-18(21(27)10-16)14-33-23(19-9-20(26)12-28-11-19)30-22-15(2)29-25(34-3)31-24(22)33/h5-6,9-12,17H,4,7-8,13-14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450233 (US10703755, Example 443) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3cc(ccc3F)C3CN4CCC3CC4)c2n1 |(-8.33,2.07,;-7.15,1.08,;-5.81,1.85,;-5.81,3.39,;-4.48,4.16,;-4.48,5.7,;-3.15,3.39,;-1.68,3.87,;-.78,2.62,;.76,2.62,;1.53,1.29,;3.07,1.29,;3.84,2.62,;3.07,3.96,;3.84,5.29,;1.53,3.96,;-1.68,1.38,;-.58,-2.73,;.91,-3.13,;1.99,-2.04,;3.48,-2.44,;3.88,-3.92,;2.79,-5.01,;1.3,-4.61,;.22,-5.7,;4.57,-1.35,;4.17,.14,;5.26,1.23,;6.75,.83,;7.15,-.66,;6.06,-1.75,;4.97,-.66,;6.3,.11,;-3.15,1.85,;-4.48,1.08,)| Show InChI InChI=1S/C26H26F2N6O/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)18-10-20(27)12-29-11-18)13-19-9-17(3-4-22(19)28)21-14-33-7-5-16(21)6-8-33/h3-4,9-12,16,21H,5-8,13-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450227 (US10703755, Example 435) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)C3CCNC3)c2n1 Show InChI InChI=1S/C23H22F2N6O/c1-13-20-22(30-23(28-13)32-2)31(21(29-20)17-7-18(24)11-27-10-17)12-16-4-3-14(8-19(16)25)15-5-6-26-9-15/h3-4,7-8,10-11,15,26H,5-6,9,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450112 (US10703755, Example 293) Show SMILES CCN1CCC(CC1)c1ccc(Cn2c(nc3c(C)nc(OC)nc23)-c2cccnc2)c(F)c1 Show InChI InChI=1S/C26H29FN6O/c1-4-32-12-9-18(10-13-32)19-7-8-21(22(27)14-19)16-33-24(20-6-5-11-28-15-20)30-23-17(2)29-26(34-3)31-25(23)33/h5-8,11,14-15,18H,4,9-10,12-13,16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450080 (US10703755, Example 260) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4CCC4)cc3F)c2n1 Show InChI InChI=1S/C23H22F2N6O/c1-14-20-22(29-23(27-14)32-2)31(21(28-20)17-9-18(24)11-26-10-17)13-16-5-4-15(8-19(16)25)12-30-6-3-7-30/h4-5,8-11H,3,6-7,12-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450054 (US10703755, Example 171) Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(nc3)C3CN4CCC3CC4)c2n1 |(-8.05,2.46,;-8.57,1.02,;-7.39,.03,;-6.06,.8,;-6.06,2.34,;-4.73,3.11,;-4.73,4.65,;-3.39,2.34,;-1.93,2.81,;-1.02,1.57,;.52,1.57,;1.29,.23,;2.83,.23,;3.6,1.57,;2.83,2.9,;3.6,4.23,;1.29,2.9,;-1.93,.32,;-1.53,-1.17,;-.04,-1.57,;1.05,-.48,;2.53,-.87,;2.93,-2.36,;1.84,-3.45,;.36,-3.05,;4.42,-2.76,;4.82,-4.25,;6.31,-4.65,;7.39,-3.56,;7,-2.07,;5.51,-1.67,;5.51,-3.21,;6.31,-3.11,;-3.39,.8,;-4.73,.03,)| Show InChI InChI=1S/C26H28FN7O/c1-3-35-26-30-16(2)23-25(32-26)34(24(31-23)19-10-20(27)13-28-12-19)14-17-4-5-22(29-11-17)21-15-33-8-6-18(21)7-9-33/h4-5,10-13,18,21H,3,6-9,14-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450162 (US10703755, Example 358) Show SMILES Cc1nc(O)nc2n(Cc3ccc(C4=CN5CCC4CC5)c(F)c3)c(nc12)-c1cncc(F)c1 |t:13,(-4.73,4.79,;-4.73,3.25,;-6.06,2.48,;-6.06,.94,;-7.39,.17,;-4.73,.17,;-3.39,.94,;-1.93,.47,;-1.53,-1.02,;-.04,-1.42,;1.05,-.33,;2.53,-.73,;2.93,-2.22,;4.42,-2.62,;4.82,-4.1,;6.31,-4.5,;7.39,-3.41,;7,-1.92,;5.51,-1.53,;5.51,-3.07,;6.38,-3.06,;1.84,-3.31,;2.24,-4.79,;.36,-2.91,;-1.02,1.71,;-1.93,2.96,;-3.39,2.48,;.52,1.71,;1.29,.38,;2.83,.38,;3.6,1.71,;2.83,3.05,;3.6,4.38,;1.29,3.05,)| Show InChI InChI=1S/C25H22F2N6O/c1-14-22-24(31-25(34)29-14)33(23(30-22)17-9-18(26)11-28-10-17)12-15-2-3-19(21(27)8-15)20-13-32-6-4-16(20)5-7-32/h2-3,8-11,13,16H,4-7,12H2,1H3,(H,29,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM450213 (US10703755, Example 418) Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@H]4C[C@@H]5CC[C@H](C4)N5C)cc3F)c2n1 |r,THB:31:30:29.24.23:27.26| Show InChI InChI=1S/C27H28F2N6O2/c1-15-24-26(33-27(31-15)36-3)35(25(32-24)17-8-18(28)13-30-12-17)14-16-4-7-21(11-23(16)29)37-22-9-19-5-6-20(10-22)34(19)2/h4,7-8,11-13,19-20,22H,5-6,9-10,14H2,1-3H3/t19-,20+,22-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent					Assay Description As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter™ HEK293 cell), which is human emb...				US Patent US10703755 (2020) BindingDB Entry DOI: 10.7270/Q28W3HBW
					More data for this Ligand-Target Pair

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