BindingDB PrimarySearch

Found 11 hits with Last Name = 'dunbar' and Initial = 'dc'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM21281 ((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cells				J Nat Prod 64: 1322-5 (2001) BindingDB Entry DOI: 10.7270/Q2C24W57
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50080528 (3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1 activation in human HeLa cells by luciferase reporter gene assay				J Nat Prod 68: 947-50 (2005) Article DOI: 10.1021/np050029m BindingDB Entry DOI: 10.7270/Q23J3GRV
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50216297 (6',7',10,11-tetramethoxyemetan \| CHEMBL50588 \| Eme...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1 activation in human HeLa cells by luciferase reporter gene assay				J Nat Prod 68: 947-50 (2005) Article DOI: 10.1021/np050029m BindingDB Entry DOI: 10.7270/Q23J3GRV
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50216297 (6',7',10,11-tetramethoxyemetan \| CHEMBL50588 \| Eme...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by luciferase reporter gene assay				J Nat Prod 68: 947-50 (2005) Article DOI: 10.1021/np050029m BindingDB Entry DOI: 10.7270/Q23J3GRV
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50478867 (CHEBI:66147 \| Klugine) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by luciferase reporter gene assay				J Nat Prod 68: 947-50 (2005) Article DOI: 10.1021/np050029m BindingDB Entry DOI: 10.7270/Q23J3GRV
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 (Homo sapiens (Human))	BDBM50478403 (CHEBI:23527 \| CYTOCHALASIN B) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	521	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of LFA1/ICAM1-mediated CFSE-labeled TPA-stimulated human HL60 cell adhesion to ICAM1 expressing human HeLa cells after 45 mins by fluoresc...				J Nat Prod 64: 559-62 (2001) Article DOI: 10.1021/np000436s BindingDB Entry DOI: 10.7270/Q26D5WSK
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50478866 (Isocephaeline) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by luciferase reporter gene assay				J Nat Prod 68: 947-50 (2005) Article DOI: 10.1021/np050029m BindingDB Entry DOI: 10.7270/Q23J3GRV
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L (Homo sapiens (Human))	BDBM50478403 (CHEBI:23527 \| CYTOCHALASIN B) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysis				J Nat Prod 66: 962-7 (2003) Article DOI: 10.1021/np030086k BindingDB Entry DOI: 10.7270/Q2M61P1C
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L (Homo sapiens (Human))	BDBM50478475 (CHEBI:3533 \| Cephaeline) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysis				J Nat Prod 66: 962-7 (2003) Article DOI: 10.1021/np030086k BindingDB Entry DOI: 10.7270/Q2M61P1C
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 (Homo sapiens (Human))	BDBM50478733 (CHEBI:67606 \| Sampangine) Show SMILES O=C1c2ccccc2-c2nccc3ccnc1c23 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of LFA1/ICAM1-mediated CFSE-labeled TPA-stimulated human HL60 cell adhesion to ICAM1 expressing human HeLa cells after 45 mins by fluoresc...				J Nat Prod 64: 559-62 (2001) Article DOI: 10.1021/np000436s BindingDB Entry DOI: 10.7270/Q26D5WSK
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L (Homo sapiens (Human))	BDBM50216297 (6',7',10,11-tetramethoxyemetan \| CHEMBL50588 \| Eme...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysis				J Nat Prod 66: 962-7 (2003) Article DOI: 10.1021/np030086k BindingDB Entry DOI: 10.7270/Q2M61P1C
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair