Compile Data Set for Download or QSAR

Found 36 hits with Last Name = 'tang-liu' and Initial = 'dd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 2 (Homo sapiens (Human))	BDBM476688 ((R)-3-Imino-2,2,5-trimethyl-5-(8- (prop-1-yn-1-yl)...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CS(=O)(=O)C(C)(C)C(=N)N1 |r| Show InChI InChI=1S/C22H22N2O2S2/c1-5-6-14-7-9-18-16(11-14)17-12-15(8-10-19(17)27-18)22(4)13-28(25,26)21(2,3)20(23)24-22/h7-12H,13H2,1-4H3,(H2,23,24)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE2 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected compounds by AnaSpec BACE2 fluorescent as...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 2 (Homo sapiens (Human))	BDBM476692 ((R)-5-(3-Fluoro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...) Show SMILES CC#Cc1ccc2sc3cc(F)c(cc3c2c1)[C@]1(C)CS(=O)(=O)C(C)(C)C(=N)N1 |r| Show InChI InChI=1S/C22H21FN2O2S2/c1-5-6-13-7-8-18-14(9-13)15-10-16(17(23)11-19(15)28-18)22(4)12-29(26,27)21(2,3)20(24)25-22/h7-11H,12H2,1-4H3,(H2,24,25)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE2 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected compounds by AnaSpec BACE2 fluorescent as...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476679 ((S)-6-(8-(3-Hydroxyprop-1-yn-1-yl) dibenzo[b,d]thi...) Show SMILES CN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(cc3c2c1)C#CCO |r| Show InChI InChI=1S/C21H19N3O2S/c1-21(12-19(26)24(2)20(22)23-21)14-6-8-18-16(11-14)15-10-13(4-3-9-25)5-7-17(15)27-18/h5-8,10-11,25H,9,12H2,1-2H3,(H2,22,23)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476666 ((S)-6-(3-Fluoro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...) Show SMILES CC#Cc1ccc2sc3cc(F)c(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C21H18FN3OS/c1-4-5-12-6-7-17-13(8-12)14-9-15(16(22)10-18(14)27-17)21(2)11-19(26)25(3)20(23)24-21/h6-10H,11H2,1-3H3,(H2,23,24)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 2 (Homo sapiens (Human))	BDBM476661 ((S)-6-(3-Chloro-5-(prop-1-yn-1-yl)- 1H-indol-2-yl)...) Show SMILES CC#Cc1ccc2[nH]c(c(Cl)c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE2 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected compounds by AnaSpec BACE2 fluorescent as...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476692 ((R)-5-(3-Fluoro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...) Show SMILES CC#Cc1ccc2sc3cc(F)c(cc3c2c1)[C@]1(C)CS(=O)(=O)C(C)(C)C(=N)N1 |r| Show InChI InChI=1S/C22H21FN2O2S2/c1-5-6-13-7-8-18-14(9-13)15-10-16(17(23)11-19(15)28-18)22(4)12-29(26,27)21(2,3)20(24)25-22/h7-11H,12H2,1-4H3,(H2,24,25)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476692 ((R)-5-(3-Fluoro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...) Show SMILES CC#Cc1ccc2sc3cc(F)c(cc3c2c1)[C@]1(C)CS(=O)(=O)C(C)(C)C(=N)N1 |r| Show InChI InChI=1S/C22H21FN2O2S2/c1-5-6-13-7-8-18-14(9-13)15-10-16(17(23)11-19(15)28-18)22(4)12-29(26,27)21(2,3)20(24)25-22/h7-11H,12H2,1-4H3,(H2,24,25)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476660 ((S)-2-Imino-3,6-dimethyl-6-(8-(prop- 1-yn-1-yl)dib...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C21H19N3OS/c1-4-5-13-6-8-17-15(10-13)16-11-14(7-9-18(16)26-17)21(2)12-19(25)24(3)20(22)23-21/h6-11H,12H2,1-3H3,(H2,22,23)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476660 ((S)-2-Imino-3,6-dimethyl-6-(8-(prop- 1-yn-1-yl)dib...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C21H19N3OS/c1-4-5-13-6-8-17-15(10-13)16-11-14(7-9-18(16)26-17)21(2)12-19(25)24(3)20(22)23-21/h6-11H,12H2,1-3H3,(H2,22,23)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476688 ((R)-3-Imino-2,2,5-trimethyl-5-(8- (prop-1-yn-1-yl)...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CS(=O)(=O)C(C)(C)C(=N)N1 |r| Show InChI InChI=1S/C22H22N2O2S2/c1-5-6-14-7-9-18-16(11-14)17-12-15(8-10-19(17)27-18)22(4)13-28(25,26)21(2,3)20(23)24-22/h7-12H,13H2,1-4H3,(H2,23,24)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476688 ((R)-3-Imino-2,2,5-trimethyl-5-(8- (prop-1-yn-1-yl)...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CS(=O)(=O)C(C)(C)C(=N)N1 |r| Show InChI InChI=1S/C22H22N2O2S2/c1-5-6-14-7-9-18-16(11-14)17-12-15(8-10-19(17)27-18)22(4)13-28(25,26)21(2,3)20(23)24-22/h7-12H,13H2,1-4H3,(H2,23,24)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476688 ((R)-3-Imino-2,2,5-trimethyl-5-(8- (prop-1-yn-1-yl)...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CS(=O)(=O)C(C)(C)C(=N)N1 |r| Show InChI InChI=1S/C22H22N2O2S2/c1-5-6-14-7-9-18-16(11-14)17-12-15(8-10-19(17)27-18)22(4)13-28(25,26)21(2,3)20(23)24-22/h7-12H,13H2,1-4H3,(H2,23,24)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476694 ((S)-6-(3-Chloro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...) Show SMILES CC#Cc1ccc2sc3cc(Cl)c(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C21H18ClN3OS/c1-4-5-12-6-7-17-13(8-12)14-9-15(16(22)10-18(14)27-17)21(2)11-19(26)25(3)20(23)24-21/h6-10H,11H2,1-3H3,(H2,23,24)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476661 ((S)-6-(3-Chloro-5-(prop-1-yn-1-yl)- 1H-indol-2-yl)...) Show SMILES CC#Cc1ccc2[nH]c(c(Cl)c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476673 ((6S)-2-Imino-3,6-dimethyl-6-(5-oxido-8- (prop-1-yn...) Show SMILES CC#Cc1ccc2c(c1)c1cc(ccc1s2=O)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C21H19N3O2S/c1-4-5-13-6-8-17-15(10-13)16-11-14(7-9-18(16)27(17)26)21(2)12-19(25)24(3)20(22)23-21/h6-11H,12H2,1-3H3,(H2,22,23)/t21-,27?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476682 ((S)-6-(8-Cyclopropyldibenzo[b,d] thiophen-2-yl)-2-...) Show SMILES CN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(cc3c2c1)C1CC1 |r| Show InChI InChI=1S/C21H21N3OS/c1-21(11-19(25)24(2)20(22)23-21)14-6-8-18-16(10-14)15-9-13(12-3-4-12)5-7-17(15)26-18/h5-10,12H,3-4,11H2,1-2H3,(H2,22,23)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476685 ((S)-2-Imino-3,6-dimethyl-6-(8-(trifluoro- methyl)d...) Show SMILES CN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(cc3c2c1)C(F)(F)F |r| Show InChI InChI=1S/C19H16F3N3OS/c1-18(9-16(26)25(2)17(23)24-18)10-3-5-14-12(7-10)13-8-11(19(20,21)22)4-6-15(13)27-14/h3-8H,9H2,1-2H3,(H2,23,24)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476670 ((S)-6-(5,5-Dioxido-8-(prop-1-yn-1-yl) dibenzo[b,d]...) Show SMILES CC#Cc1ccc2c(c1)-c1cc(ccc1S2(=O)=O)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C21H19N3O3S/c1-4-5-13-6-8-17-15(10-13)16-11-14(7-9-18(16)28(17,26)27)21(2)12-19(25)24(3)20(22)23-21/h6-11H,12H2,1-3H3,(H2,22,23)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476687 ((R)-5,5-Difluoro-4-methyl-4-(8-(prop- 1-yn-1-yl)di...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@@]1(C)NC(=N)OCC1(F)F |r| Show InChI InChI=1S/C20H16F2N2OS/c1-3-4-12-5-7-16-14(9-12)15-10-13(6-8-17(15)26-16)19(2)20(21,22)11-25-18(23)24-19/h5-10H,11H2,1-2H3,(H2,23,24)/t19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476678 ((S)-2-Imino-6-(8-(3-methoxyprop-1- yn-1-yl)dibenzo...) Show SMILES COCC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C22H21N3O2S/c1-22(13-20(26)25(2)21(23)24-22)15-7-9-19-17(12-15)16-11-14(5-4-10-27-3)6-8-18(16)28-19/h6-9,11-12H,10,13H2,1-3H3,(H2,23,24)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	218	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476693 ((R)-3-Imino-1,5-dimethyl-5-(8-(prop- 1-yn-1-yl)dib...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CN(C)C(=O)C(=N)N1 |r| Show InChI InChI=1S/C21H19N3OS/c1-4-5-13-6-8-17-15(10-13)16-11-14(7-9-18(16)26-17)21(2)12-24(3)20(25)19(22)23-21/h6-11H,12H2,1-3H3,(H2,22,23)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476691 ((S)-2-Imino-3-(2-methoxyethyl)-6- methyl-6-(8-(pro...) Show SMILES COCCN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(cc3c2c1)C#CC |r| Show InChI InChI=1S/C23H23N3O2S/c1-4-5-15-6-8-19-17(12-15)18-13-16(7-9-20(18)29-19)23(2)14-21(27)26(10-11-28-3)22(24)25-23/h6-9,12-13H,10-11,14H2,1-3H3,(H2,24,25)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476690 ((S)-3-(2,2-Difluoroethyl)-2-imino-6- methyl-6-(8-(...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CC(=O)N(CC(F)F)C(=N)N1 |r| Show InChI InChI=1S/C22H19F2N3OS/c1-3-4-13-5-7-17-15(9-13)16-10-14(6-8-18(16)29-17)22(2)11-20(28)27(12-19(23)24)21(25)26-22/h5-10,19H,11-12H2,1-2H3,(H2,25,26)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476689 ((R)-3-Imino-2,5-dimethyl-5-(8-(prop- 1-yn-1-yl)dib...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CS(=O)(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C20H19N3O2S2/c1-4-5-13-6-8-17-15(10-13)16-11-14(7-9-18(16)26-17)20(2)12-27(24,25)23(3)19(21)22-20/h6-11H,12H2,1-3H3,(H2,21,22)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476684 ((S)-6-(8-(Diethylamino)dibenzo[b,d] thiophen-2-yl)...) Show SMILES CCN(CC)c1ccc2sc3ccc(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C22H26N4OS/c1-5-26(6-2)15-8-10-19-17(12-15)16-11-14(7-9-18(16)28-19)22(3)13-20(27)25(4)21(23)24-22/h7-12H,5-6,13H2,1-4H3,(H2,23,24)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476683 ((S)-8-(2-Imino-1,4-dimethyl-6- oxohexahydropyrimid...) Show SMILES CN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(cc3c2c1)C(N)=O |r| Show InChI InChI=1S/C19H18N4O2S/c1-19(9-16(24)23(2)18(21)22-19)11-4-6-15-13(8-11)12-7-10(17(20)25)3-5-14(12)26-15/h3-8H,9H2,1-2H3,(H2,20,25)(H2,21,22)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476681 ((S)-2-Imino-3,6-dimethyl-6-(8-propyl- dibenzo[b,d]...) Show SMILES CCCc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C21H23N3OS/c1-4-5-13-6-8-17-15(10-13)16-11-14(7-9-18(16)26-17)21(2)12-19(25)24(3)20(22)23-21/h6-11H,4-5,12H2,1-3H3,(H2,22,23)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476680 ((S)-6-(8-Bromodibenzo[b,d]thiophen- 2-yl)-2-imino-...) Show SMILES CN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(Br)cc3c2c1 |r| Show InChI InChI=1S/C18H16BrN3OS/c1-18(9-16(23)22(2)17(20)21-18)10-3-5-14-12(7-10)13-8-11(19)4-6-15(13)24-14/h3-8H,9H2,1-2H3,(H2,20,21)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476677 ((S)-8-(2-Imino-1,4-dimethyl-6- oxohexahydropyrimid...) Show SMILES CN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(cc3c2c1)C#N |r| Show InChI InChI=1S/C19H16N4OS/c1-19(9-17(24)23(2)18(21)22-19)12-4-6-16-14(8-12)13-7-11(10-20)3-5-15(13)25-16/h3-8H,9H2,1-2H3,(H2,21,22)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476676 ((S)-6-(9,9-Difluoro-6-(prop-1-yn-1-yl)- 9H-fluoren...) Show SMILES CC#Cc1ccc2c(c1)-c1cc(ccc1C2(F)F)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C22H19F2N3O/c1-4-5-13-6-8-17-15(10-13)16-11-14(7-9-18(16)22(17,23)24)21(2)12-19(28)27(3)20(25)26-21/h6-11H,12H2,1-3H3,(H2,25,26)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476675 ((S)-6-(9,9-Dimethyl-6-(prop-1-yn-1-yl)- 9H-fluoren...) Show SMILES CC#Cc1ccc2c(c1)-c1cc(ccc1C2(C)C)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C24H25N3O/c1-6-7-15-8-10-19-17(12-15)18-13-16(9-11-20(18)23(19,2)3)24(4)14-21(28)27(5)22(25)26-24/h8-13H,14H2,1-5H3,(H2,25,26)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM476686 ((R)-6-Cyclopropyl-2-imino-3-methyl- 6-(8-(prop-1-y...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@@]1(CC(=O)N(C)C(=N)N1)C1CC1 |r| Show InChI InChI=1S/C23H21N3OS/c1-3-4-14-5-9-19-17(11-14)18-12-16(8-10-20(18)28-19)23(15-6-7-15)13-21(27)26(2)22(24)25-23/h5,8-12,15H,6-7,13H2,1-2H3,(H2,24,25)/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM476694 ((S)-6-(3-Chloro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...) Show SMILES CC#Cc1ccc2sc3cc(Cl)c(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C21H18ClN3OS/c1-4-5-12-6-7-17-13(8-12)14-9-15(16(22)10-18(14)27-17)21(2)11-19(26)25(3)20(23)24-21/h6-10H,11H2,1-3H3,(H2,23,24)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description Cathepsin D (Cat D) is a major intercellular member of the mammalian aspartic proteinase family and is thought to be in the normal degradation of int...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM476692 ((R)-5-(3-Fluoro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...) Show SMILES CC#Cc1ccc2sc3cc(F)c(cc3c2c1)[C@]1(C)CS(=O)(=O)C(C)(C)C(=N)N1 |r| Show InChI InChI=1S/C22H21FN2O2S2/c1-5-6-13-7-8-18-14(9-13)15-10-16(17(23)11-19(15)28-18)22(4)12-29(26,27)21(2,3)20(24)25-22/h7-11H,12H2,1-4H3,(H2,24,25)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description Cathepsin D (Cat D) is a major intercellular member of the mammalian aspartic proteinase family and is thought to be in the normal degradation of int...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM476660 ((S)-2-Imino-3,6-dimethyl-6-(8-(prop- 1-yn-1-yl)dib...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1 |r| Show InChI InChI=1S/C21H19N3OS/c1-4-5-13-6-8-17-15(10-13)16-11-14(7-9-18(16)26-17)21(2)12-19(25)24(3)20(22)23-21/h6-11H,12H2,1-3H3,(H2,22,23)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description Cathepsin D (Cat D) is a major intercellular member of the mammalian aspartic proteinase family and is thought to be in the normal degradation of int...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM476688 ((R)-3-Imino-2,2,5-trimethyl-5-(8- (prop-1-yn-1-yl)...) Show SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CS(=O)(=O)C(C)(C)C(=N)N1 |r| Show InChI InChI=1S/C22H22N2O2S2/c1-5-6-14-7-9-18-16(11-14)17-12-15(8-10-19(17)27-18)22(4)13-28(25,26)21(2,3)20(23)24-22/h7-12H,13H2,1-4H3,(H2,23,24)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
ALLGENESIS BIOTHERAPEUTICS, INC. US Patent					Assay Description Cathepsin D (Cat D) is a major intercellular member of the mammalian aspartic proteinase family and is thought to be in the normal degradation of int...				US Patent US10870635 (2020) BindingDB Entry DOI: 10.7270/Q2474DXV
					More data for this Ligand-Target Pair