Compile Data Set for Download or QSAR

Found 193 hits with Last Name = 'old' and Initial = 'dw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202319 (US9540357, example 14 | US9540357, example 15) Show SMILES CCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C31H32ClNO4/c1-2-22-20-26(32)12-15-28(22)24-6-3-7-25(19-24)29(34)16-13-27-14-17-30(35)33(27)18-4-5-21-8-10-23(11-9-21)31(36)37/h3,6-13,15-16,19-20,27,29,34H,2,4-5,14,17-18H2,1H3,(H,36,37)/b16-13+/t27-,29?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6	-46.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202325 (US9540357, example 16 | US9540357, example 17) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(c1)-c1ccc(Cl)cc1C(F)(F)F |r| Show InChI InChI=1S/C30H27ClF3NO4/c31-23-10-13-25(26(18-23)30(32,33)34)21-4-1-5-22(17-21)27(36)14-11-24-12-15-28(37)35(24)16-2-3-19-6-8-20(9-7-19)29(38)39/h1,4-11,13-14,17-18,24,27,36H,2-3,12,15-16H2,(H,38,39)/b14-11+/t24-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11	-45.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202318 (US9540357, example 13) Show SMILES Cc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H30ClNO4/c1-20-18-25(31)11-14-27(20)23-5-2-6-24(19-23)28(33)15-12-26-13-16-29(34)32(26)17-3-4-21-7-9-22(10-8-21)30(35)36/h2,5-12,14-15,18-19,26,28,33H,3-4,13,16-17H2,1H3,(H,35,36)/b15-12+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	23	-43.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202307 (US9540357, example 10 | US9540357, example 9) Show SMILES Cc1cc(O)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H31NO5/c1-20-18-26(32)13-14-27(20)23-5-2-6-24(19-23)28(33)15-11-25-12-16-29(34)31(25)17-3-4-21-7-9-22(10-8-21)30(35)36/h2,5-11,13-15,18-19,25,28,32-33H,3-4,12,16-17H2,1H3,(H,35,36)/b15-11+/t25-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	25	-43.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202310 (US9540357, example 11 | US9540357, example 12) Show SMILES Cc1cc(F)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H30FNO4/c1-20-18-25(31)11-14-27(20)23-5-2-6-24(19-23)28(33)15-12-26-13-16-29(34)32(26)17-3-4-21-7-9-22(10-8-21)30(35)36/h2,5-12,14-15,18-19,26,28,33H,3-4,13,16-17H2,1H3,(H,35,36)/b15-12+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	53	-41.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202331 (US9540357, example 20 | US9540357, example 21) Show SMILES Cc1cc(Cl)cc(C)c1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C31H32ClNO4/c1-20-17-26(32)18-21(2)30(20)25-7-3-6-24(19-25)28(34)14-12-27-13-15-29(35)33(27)16-4-5-22-8-10-23(11-9-22)31(36)37/h3,6-12,14,17-19,27-28,34H,4-5,13,15-16H2,1-2H3,(H,36,37)/b14-12+/t27-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	60	-41.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202345 (US9540357, example 24 | US9540357, example 25) Show SMILES CCCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C32H34ClNO4/c1-2-5-24-21-27(33)13-16-29(24)25-7-3-8-26(20-25)30(35)17-14-28-15-18-31(36)34(28)19-4-6-22-9-11-23(12-10-22)32(37)38/h3,7-14,16-17,20-21,28,30,35H,2,4-6,15,18-19H2,1H3,(H,37,38)/b17-14+/t28-,30?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	130	-39.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202340 (US9540357, example 22 | US9540357, example 23) Show SMILES Cc1c(Cl)c(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H29Cl2NO4/c1-19-25(13-14-26(31)29(19)32)22-5-2-6-23(18-22)27(34)15-11-24-12-16-28(35)33(24)17-3-4-20-7-9-21(10-8-20)30(36)37/h2,5-11,13-15,18,24,27,34H,3-4,12,16-17H2,1H3,(H,36,37)/b15-11+/t24-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	140	-39.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202305 (US9540357, example 7 | US9540357, example 8) Show SMILES Cc1ccccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H31NO4/c1-21-6-2-3-10-27(21)24-8-4-9-25(20-24)28(32)17-15-26-16-18-29(33)31(26)19-5-7-22-11-13-23(14-12-22)30(34)35/h2-4,6,8-15,17,20,26,28,32H,5,7,16,18-19H2,1H3,(H,34,35)/b17-15+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	159	-38.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202452 (US9540357, example 30 | US9540357, example 31) Show SMILES CC(C)c1cc(O)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C32H35NO5/c1-21(2)29-20-27(34)14-15-28(29)24-6-3-7-25(19-24)30(35)16-12-26-13-17-31(36)33(26)18-4-5-22-8-10-23(11-9-22)32(37)38/h3,6-12,14-16,19-21,26,30,34-35H,4-5,13,17-18H2,1-2H3,(H,37,38)/b16-12+/t26-,30?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	211	-38.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202319 (US9540357, example 14 | US9540357, example 15) Show SMILES CCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C31H32ClNO4/c1-2-22-20-26(32)12-15-28(22)24-6-3-7-25(19-24)29(34)16-13-27-14-17-30(35)33(27)18-4-5-21-8-10-23(11-9-21)31(36)37/h3,6-13,15-16,19-20,27,29,34H,2,4-5,14,17-18H2,1H3,(H,36,37)/b16-13+/t27-,29?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	216	-38.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202394 (US9540357, example 28 | US9540357, example 29) Show SMILES CCCCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C33H36ClNO4/c1-2-3-7-26-22-28(34)14-17-30(26)25-8-4-9-27(21-25)31(36)18-15-29-16-19-32(37)35(29)20-5-6-23-10-12-24(13-11-23)33(38)39/h4,8-15,17-18,21-22,29,31,36H,2-3,5-7,16,19-20H2,1H3,(H,38,39)/b18-15+/t29-,31?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	319	-37.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202325 (US9540357, example 16 | US9540357, example 17) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(c1)-c1ccc(Cl)cc1C(F)(F)F |r| Show InChI InChI=1S/C30H27ClF3NO4/c31-23-10-13-25(26(18-23)30(32,33)34)21-4-1-5-22(17-21)27(36)14-11-24-12-15-28(37)35(24)16-2-3-19-6-8-20(9-7-19)29(38)39/h1,4-11,13-14,17-18,24,27,36H,2-3,12,15-16H2,(H,38,39)/b14-11+/t24-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	332	-37.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202472 (US9540357, example 34 | US9540357, example 35) Show SMILES Cc1cc(Cl)ccc1-c1cc(F)cc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H29ClFNO4/c1-19-15-24(31)8-11-27(19)22-16-23(18-25(32)17-22)28(34)12-9-26-10-13-29(35)33(26)14-2-3-20-4-6-21(7-5-20)30(36)37/h4-9,11-12,15-18,26,28,34H,2-3,10,13-14H2,1H3,(H,36,37)/b12-9+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	352	-36.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202460 (US9540357, example 32 | US9540357, example 33) Show SMILES Cc1cc(Cl)ccc1-c1ccc(s1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C28H28ClNO4S/c1-18-17-21(29)8-11-23(18)25-13-14-26(35-25)24(31)12-9-22-10-15-27(32)30(22)16-2-3-19-4-6-20(7-5-19)28(33)34/h4-9,11-14,17,22,24,31H,2-3,10,15-16H2,1H3,(H,33,34)/b12-9+/t22-,24?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	536	-35.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202452 (US9540357, example 30 | US9540357, example 31) Show SMILES CC(C)c1cc(O)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C32H35NO5/c1-21(2)29-20-27(34)14-15-28(29)24-6-3-7-25(19-24)30(35)16-12-26-13-17-31(36)33(26)18-4-5-22-8-10-23(11-9-22)32(37)38/h3,6-12,14-16,19-21,26,30,34-35H,4-5,13,17-18H2,1-2H3,(H,37,38)/b16-12+/t26-,30?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	582	-35.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202329 (US9540357, example 18 | US9540357, example 19) Show SMILES OCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H30ClNO5/c31-25-10-13-27(24(18-25)19-33)22-4-1-5-23(17-22)28(34)14-11-26-12-15-29(35)32(26)16-2-3-20-6-8-21(9-7-20)30(36)37/h1,4-11,13-14,17-18,26,28,33-34H,2-3,12,15-16,19H2,(H,36,37)/b14-11+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	658	-35.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202354 (US9540357, example 26 | US9540357, example 27) Show SMILES CC(C)(C)c1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C33H36ClNO4/c1-33(2,3)29-21-26(34)13-16-28(29)24-7-4-8-25(20-24)30(36)17-14-27-15-18-31(37)35(27)19-5-6-22-9-11-23(12-10-22)32(38)39/h4,7-14,16-17,20-21,27,30,36H,5-6,15,18-19H2,1-3H3,(H,38,39)/b17-14+/t27-,30?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	757	-34.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202331 (US9540357, example 20 | US9540357, example 21) Show SMILES Cc1cc(Cl)cc(C)c1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C31H32ClNO4/c1-20-17-26(32)18-21(2)30(20)25-7-3-6-24(19-25)28(34)14-12-27-13-15-29(35)33(27)16-4-5-22-8-10-23(11-9-22)31(36)37/h3,6-12,14,17-19,27-28,34H,4-5,13,15-16H2,1-2H3,(H,36,37)/b14-12+/t27-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	955	-34.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202485 (US9540357, example 36 | US9540357, example 37) Show SMILES Cc1cc(Cl)ccc1-c1cc(ccc1F)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H29ClFNO4/c1-19-17-23(31)9-12-25(19)26-18-22(8-13-27(26)32)28(34)14-10-24-11-15-29(35)33(24)16-2-3-20-4-6-21(7-5-20)30(36)37/h4-10,12-14,17-18,24,28,34H,2-3,11,15-16H2,1H3,(H,36,37)/b14-10+/t24-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.08E+3	-34.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202305 (US9540357, example 7 | US9540357, example 8) Show SMILES Cc1ccccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H31NO4/c1-21-6-2-3-10-27(21)24-8-4-9-25(20-24)28(32)17-15-26-16-18-29(33)31(26)19-5-7-22-11-13-23(14-12-22)30(34)35/h2-4,6,8-15,17,20,26,28,32H,5,7,16,18-19H2,1H3,(H,34,35)/b17-15+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.15E+3	-33.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202290 (US9540357, example 1 | US9540357, example 2) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C23H24BrNO4/c24-19-5-1-4-18(15-19)21(26)12-10-20-11-13-22(27)25(20)14-2-3-16-6-8-17(9-7-16)23(28)29/h1,4-10,12,15,20-21,26H,2-3,11,13-14H2,(H,28,29)/b12-10+/t20-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.21E+3	-33.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202345 (US9540357, example 24 | US9540357, example 25) Show SMILES CCCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C32H34ClNO4/c1-2-5-24-21-27(33)13-16-29(24)25-7-3-8-26(20-25)30(35)17-14-28-15-18-31(36)34(28)19-4-6-22-9-11-23(12-10-22)32(37)38/h3,7-14,16-17,20-21,28,30,35H,2,4-6,15,18-19H2,1H3,(H,37,38)/b17-14+/t28-,30?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.31E+3	-33.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202310 (US9540357, example 11 | US9540357, example 12) Show SMILES Cc1cc(F)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H30FNO4/c1-20-18-25(31)11-14-27(20)23-5-2-6-24(19-23)28(33)15-12-26-13-16-29(34)32(26)17-3-4-21-7-9-22(10-8-21)30(35)36/h2,5-12,14-15,18-19,26,28,33H,3-4,13,16-17H2,1H3,(H,35,36)/b15-12+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.34E+3	>-33.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202290 (US9540357, example 1 | US9540357, example 2) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C23H24BrNO4/c24-19-5-1-4-18(15-19)21(26)12-10-20-11-13-22(27)25(20)14-2-3-16-6-8-17(9-7-16)23(28)29/h1,4-10,12,15,20-21,26H,2-3,11,13-14H2,(H,28,29)/b12-10+/t20-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.04E+3	-32.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202340 (US9540357, example 22 | US9540357, example 23) Show SMILES Cc1c(Cl)c(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H29Cl2NO4/c1-19-25(13-14-26(31)29(19)32)22-5-2-6-23(18-22)27(34)15-11-24-12-16-28(35)33(24)17-3-4-20-7-9-21(10-8-20)30(36)37/h2,5-11,13-15,18,24,27,34H,3-4,12,16-17H2,1H3,(H,36,37)/b15-11+/t24-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.34E+3	-32.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202307 (US9540357, example 10 | US9540357, example 9) Show SMILES Cc1cc(O)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H31NO5/c1-20-18-26(32)13-14-27(20)23-5-2-6-24(19-23)28(33)15-11-25-12-16-29(34)31(25)17-3-4-21-7-9-22(10-8-21)30(35)36/h2,5-11,13-15,18-19,25,28,32-33H,3-4,12,16-17H2,1H3,(H,35,36)/b15-11+/t25-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.32E+3	-31.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202318 (US9540357, example 13) Show SMILES Cc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H30ClNO4/c1-20-18-25(31)11-14-27(20)23-5-2-6-24(19-23)28(33)15-12-26-13-16-29(34)32(26)17-3-4-21-7-9-22(10-8-21)30(35)36/h2,5-12,14-15,18-19,26,28,33H,3-4,13,16-17H2,1H3,(H,35,36)/b15-12+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.32E+3	-30.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202472 (US9540357, example 34 | US9540357, example 35) Show SMILES Cc1cc(Cl)ccc1-c1cc(F)cc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H29ClFNO4/c1-19-15-24(31)8-11-27(19)22-16-23(18-25(32)17-22)28(34)12-9-26-10-13-29(35)33(26)14-2-3-20-4-6-21(7-5-20)30(36)37/h4-9,11-12,15-18,26,28,34H,2-3,10,13-14H2,1H3,(H,36,37)/b12-9+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.34E+3	-30.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202485 (US9540357, example 36 | US9540357, example 37) Show SMILES Cc1cc(Cl)ccc1-c1cc(ccc1F)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H29ClFNO4/c1-19-17-23(31)9-12-25(19)26-18-22(8-13-27(26)32)28(34)14-10-24-11-15-29(35)33(24)16-2-3-20-4-6-21(7-5-20)30(36)37/h4-10,12-14,17-18,24,28,34H,2-3,11,15-16H2,1H3,(H,36,37)/b14-10+/t24-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.48E+3	-30.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202460 (US9540357, example 32 | US9540357, example 33) Show SMILES Cc1cc(Cl)ccc1-c1ccc(s1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C28H28ClNO4S/c1-18-17-21(29)8-11-23(18)25-13-14-26(35-25)24(31)12-9-22-10-15-27(32)30(22)16-2-3-19-4-6-20(7-5-19)28(33)34/h4-9,11-14,17,22,24,31H,2-3,10,15-16H2,1H3,(H,33,34)/b12-9+/t22-,24?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.83E+3	-30.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202293 (US9540357, example 3 | US9540357, example 4) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C23H25NO4/c25-21(18-6-2-1-3-7-18)14-12-20-13-15-22(26)24(20)16-4-5-17-8-10-19(11-9-17)23(27)28/h1-3,6-12,14,20-21,25H,4-5,13,15-16H2,(H,27,28)/b14-12+/t20-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.97E+3	-30.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202394 (US9540357, example 28 | US9540357, example 29) Show SMILES CCCCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C33H36ClNO4/c1-2-3-7-26-22-28(34)14-17-30(26)25-8-4-9-27(21-25)31(36)18-15-29-16-19-32(37)35(29)20-5-6-23-10-12-24(13-11-23)33(38)39/h4,8-15,17-18,21-22,29,31,36H,2-3,5-7,16,19-20H2,1H3,(H,38,39)/b18-15+/t29-,31?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.16E+3	-30.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202296 (US9540357, example 5 | US9540357, example 6) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29NO4/c31-27(25-10-4-9-24(20-25)22-7-2-1-3-8-22)17-15-26-16-18-28(32)30(26)19-5-6-21-11-13-23(14-12-21)29(33)34/h1-4,7-15,17,20,26-27,31H,5-6,16,18-19H2,(H,33,34)/b17-15+/t26-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.71E+3	-29.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202290 (US9540357, example 1 | US9540357, example 2) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C23H24BrNO4/c24-19-5-1-4-18(15-19)21(26)12-10-20-11-13-22(27)25(20)14-2-3-16-6-8-17(9-7-16)23(28)29/h1,4-10,12,15,20-21,26H,2-3,11,13-14H2,(H,28,29)/b12-10+/t20-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.49E+3	-29.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202485 (US9540357, example 36 | US9540357, example 37) Show SMILES Cc1cc(Cl)ccc1-c1cc(ccc1F)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H29ClFNO4/c1-19-17-23(31)9-12-25(19)26-18-22(8-13-27(26)32)28(34)14-10-24-11-15-29(35)33(24)16-2-3-20-4-6-21(7-5-20)30(36)37/h4-10,12-14,17-18,24,28,34H,2-3,11,15-16H2,1H3,(H,36,37)/b14-10+/t24-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.49E+3	-29.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202296 (US9540357, example 5 | US9540357, example 6) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29NO4/c31-27(25-10-4-9-24(20-25)22-7-2-1-3-8-22)17-15-26-16-18-28(32)30(26)19-5-6-21-11-13-23(14-12-21)29(33)34/h1-4,7-15,17,20,26-27,31H,5-6,16,18-19H2,(H,33,34)/b17-15+/t26-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.56E+3	-28.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202354 (US9540357, example 26 | US9540357, example 27) Show SMILES CC(C)(C)c1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C33H36ClNO4/c1-33(2,3)29-21-26(34)13-16-28(29)24-7-4-8-25(20-24)30(36)17-14-27-15-18-31(37)35(27)19-5-6-22-9-11-23(12-10-22)32(38)39/h4,7-14,16-17,20-21,27,30,36H,5-6,15,18-19H2,1-3H3,(H,38,39)/b17-14+/t27-,30?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.85E+3	-28.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202305 (US9540357, example 7 | US9540357, example 8) Show SMILES Cc1ccccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H31NO4/c1-21-6-2-3-10-27(21)24-8-4-9-25(20-24)28(32)17-15-26-16-18-29(33)31(26)19-5-7-22-11-13-23(14-12-22)30(34)35/h2-4,6,8-15,17,20,26,28,32H,5,7,16,18-19H2,1H3,(H,34,35)/b17-15+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202305 (US9540357, example 7 | US9540357, example 8) Show SMILES Cc1ccccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H31NO4/c1-21-6-2-3-10-27(21)24-8-4-9-25(20-24)28(32)17-15-26-16-18-29(33)31(26)19-5-7-22-11-13-23(14-12-22)30(34)35/h2-4,6,8-15,17,20,26,28,32H,5,7,16,18-19H2,1H3,(H,34,35)/b17-15+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202307 (US9540357, example 10 | US9540357, example 9) Show SMILES Cc1cc(O)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H31NO5/c1-20-18-26(32)13-14-27(20)23-5-2-6-24(19-23)28(33)15-11-25-12-16-29(34)31(25)17-3-4-21-7-9-22(10-8-21)30(35)36/h2,5-11,13-15,18-19,25,28,32-33H,3-4,12,16-17H2,1H3,(H,35,36)/b15-11+/t25-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202307 (US9540357, example 10 | US9540357, example 9) Show SMILES Cc1cc(O)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H31NO5/c1-20-18-26(32)13-14-27(20)23-5-2-6-24(19-23)28(33)15-11-25-12-16-29(34)31(25)17-3-4-21-7-9-22(10-8-21)30(35)36/h2,5-11,13-15,18-19,25,28,32-33H,3-4,12,16-17H2,1H3,(H,35,36)/b15-11+/t25-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202310 (US9540357, example 11 | US9540357, example 12) Show SMILES Cc1cc(F)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H30FNO4/c1-20-18-25(31)11-14-27(20)23-5-2-6-24(19-23)28(33)15-12-26-13-16-29(34)32(26)17-3-4-21-7-9-22(10-8-21)30(35)36/h2,5-12,14-15,18-19,26,28,33H,3-4,13,16-17H2,1H3,(H,35,36)/b15-12+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202310 (US9540357, example 11 | US9540357, example 12) Show SMILES Cc1cc(F)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H30FNO4/c1-20-18-25(31)11-14-27(20)23-5-2-6-24(19-23)28(33)15-12-26-13-16-29(34)32(26)17-3-4-21-7-9-22(10-8-21)30(35)36/h2,5-12,14-15,18-19,26,28,33H,3-4,13,16-17H2,1H3,(H,35,36)/b15-12+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202319 (US9540357, example 14 | US9540357, example 15) Show SMILES CCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C31H32ClNO4/c1-2-22-20-26(32)12-15-28(22)24-6-3-7-25(19-24)29(34)16-13-27-14-17-30(35)33(27)18-4-5-21-8-10-23(11-9-21)31(36)37/h3,6-13,15-16,19-20,27,29,34H,2,4-5,14,17-18H2,1H3,(H,36,37)/b16-13+/t27-,29?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202319 (US9540357, example 14 | US9540357, example 15) Show SMILES CCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C31H32ClNO4/c1-2-22-20-26(32)12-15-28(22)24-6-3-7-25(19-24)29(34)16-13-27-14-17-30(35)33(27)18-4-5-21-8-10-23(11-9-21)31(36)37/h3,6-13,15-16,19-20,27,29,34H,2,4-5,14,17-18H2,1H3,(H,36,37)/b16-13+/t27-,29?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202325 (US9540357, example 16 | US9540357, example 17) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(c1)-c1ccc(Cl)cc1C(F)(F)F |r| Show InChI InChI=1S/C30H27ClF3NO4/c31-23-10-13-25(26(18-23)30(32,33)34)21-4-1-5-22(17-21)27(36)14-11-24-12-15-28(37)35(24)16-2-3-19-6-8-20(9-7-19)29(38)39/h1,4-11,13-14,17-18,24,27,36H,2-3,12,15-16H2,(H,38,39)/b14-11+/t24-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202325 (US9540357, example 16 | US9540357, example 17) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(c1)-c1ccc(Cl)cc1C(F)(F)F |r| Show InChI InChI=1S/C30H27ClF3NO4/c31-23-10-13-25(26(18-23)30(32,33)34)21-4-1-5-22(17-21)27(36)14-11-24-12-15-28(37)35(24)16-2-3-19-6-8-20(9-7-19)29(38)39/h1,4-11,13-14,17-18,24,27,36H,2-3,12,15-16H2,(H,38,39)/b14-11+/t24-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202329 (US9540357, example 18 | US9540357, example 19) Show SMILES OCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H30ClNO5/c31-25-10-13-27(24(18-25)19-33)22-4-1-5-23(17-22)28(34)14-11-26-12-15-29(35)32(26)16-2-3-20-6-8-21(9-7-20)30(36)37/h1,4-11,13-14,17-18,26,28,33-34H,2-3,12,15-16,19H2,(H,36,37)/b14-11+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202329 (US9540357, example 18 | US9540357, example 19) Show SMILES OCc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C30H30ClNO5/c31-25-10-13-27(24(18-25)19-33)22-4-1-5-23(17-22)28(34)14-11-26-12-15-29(35)32(26)16-2-3-20-6-8-21(9-7-20)30(36)37/h1,4-11,13-14,17-18,26,28,33-34H,2-3,12,15-16,19H2,(H,36,37)/b14-11+/t26-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair

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