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Compile Data Set for Download or QSAR

Found 33 hits with Last Name = 'eunkyeong kim' and Initial = 'e'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))
BDBM50085415
PNG
(3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)
Show SMILES Oc1c(Br)cc(\C=C2/C(=O)Nc3ccc(I)cc23)cc1Br
Show InChI InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)/b10-3-
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n/an/a 7.40n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50085415
PNG
(3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)
Show SMILES Oc1c(Br)cc(\C=C2/C(=O)Nc3ccc(I)cc23)cc1Br
Show InChI InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)/b10-3-
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n/an/a 7.5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50085415
PNG
(3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)
Show SMILES Oc1c(Br)cc(\C=C2/C(=O)Nc3ccc(I)cc23)cc1Br
Show InChI InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)/b10-3-
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n/an/a 13n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))
BDBM50556317
PNG
(CHEMBL4795732)
Show SMILES CCN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3c(OC)cccc3n2)c1
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n/an/a 229n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))
BDBM50554673
PNG
(CHEMBL4760204)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(N)=O |r|
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n/an/a 230n/an/an/an/an/an/a


TBA

Assay Description
Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01451
BindingDB Entry DOI: 10.7270/Q2W38105
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))
BDBM50556315
PNG
(CHEMBL4745330)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12
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n/an/a 370n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))
BDBM50556319
PNG
(CHEMBL4800457)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)-n4cnc(C)c4)c3)ccc12
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n/an/a 414n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1


(Homo sapiens (Human))
BDBM50556317
PNG
(CHEMBL4795732)
Show SMILES CCN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3c(OC)cccc3n2)c1
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n/an/a 538n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human DDR1 using KKSRGDYMTMQIG as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))
BDBM50556318
PNG
(CHEMBL4781021)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)N4CCOCC4)c3)ccc12
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n/an/a 616n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556317
PNG
(CHEMBL4795732)
Show SMILES CCN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3c(OC)cccc3n2)c1
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n/an/a 888n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556319
PNG
(CHEMBL4800457)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)-n4cnc(C)c4)c3)ccc12
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n/an/a 1.10E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))
BDBM50556316
PNG
(CHEMBL4743339)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCOCC5)c(c4)C(F)(F)F)c3)ccc12
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n/an/a 1.44E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556315
PNG
(CHEMBL4745330)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12
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n/an/a 1.46E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556318
PNG
(CHEMBL4781021)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)N4CCOCC4)c3)ccc12
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n/an/a 1.49E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50556317
PNG
(CHEMBL4795732)
Show SMILES CCN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3c(OC)cccc3n2)c1
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n/an/a 1.67E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRKA using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM2579
PNG
((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r|
Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1
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n/an/a 1.67E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRKA using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556317
PNG
(CHEMBL4795732)
Show SMILES CCN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3c(OC)cccc3n2)c1
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n/an/a 2.23E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1


(Homo sapiens (Human))
BDBM50556315
PNG
(CHEMBL4745330)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12
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n/an/a 2.25E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human DDR1 using KKSRGDYMTMQIG as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1


(Homo sapiens (Human))
BDBM2579
PNG
((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r|
Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1
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n/an/a 2.89E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human DDR1 using KKSRGDYMTMQIG as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556315
PNG
(CHEMBL4745330)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12
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n/an/a 2.94E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556316
PNG
(CHEMBL4743339)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCOCC5)c(c4)C(F)(F)F)c3)ccc12
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n/an/a 4.57E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))
BDBM50556314
PNG
(CHEMBL4782569)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c3)ccc12
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n/an/a 4.79E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556318
PNG
(CHEMBL4781021)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)N4CCOCC4)c3)ccc12
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n/an/a 5.87E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556319
PNG
(CHEMBL4800457)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)-n4cnc(C)c4)c3)ccc12
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n/an/a 9.28E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556314
PNG
(CHEMBL4782569)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c3)ccc12
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n/an/a 9.45E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))
BDBM50554676
PNG
(CHEMBL4788427)
Show SMILES [#6]-[#7]-c1ccc(cc1)-[#6](=O)-[#7]-[#6]-[#6]-n1cc(\[#6]=[#6]-2\[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]-2=O)c(n1)-c1ccccc1
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n/an/a 1.64E+4n/an/an/an/an/an/a


TBA

Assay Description
Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01451
BindingDB Entry DOI: 10.7270/Q2W38105
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))
BDBM50554672
PNG
(CHEMBL4758139)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@@H]1C(=O)N[C@@H]([C@@H](C)O)C(O)=O |r|
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n/an/a 2.90E+4n/an/an/an/an/an/a


TBA

Assay Description
Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01451
BindingDB Entry DOI: 10.7270/Q2W38105
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))
BDBM50554674
PNG
(CHEMBL4777323)
Show SMILES O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]/c2cn(nc2-c2ccccc2)-c2ccccc2)-[#6](=O)-[#7]-1
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n/an/a 3.22E+4n/an/an/an/an/an/a


TBA

Assay Description
Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01451
BindingDB Entry DOI: 10.7270/Q2W38105
More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50556315
PNG
(CHEMBL4745330)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12
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n/an/a 3.40E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRKA using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556316
PNG
(CHEMBL4743339)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCOCC5)c(c4)C(F)(F)F)c3)ccc12
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n/an/a 4.09E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))
BDBM50554675
PNG
(CHEMBL4792348)
Show SMILES O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]/c2cn(-[#6]-c3ccccc3)nc2-c2ccccc2)-[#6](=O)-[#7]-1
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n/an/a 5.27E+4n/an/an/an/an/an/a


TBA

Assay Description
Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01451
BindingDB Entry DOI: 10.7270/Q2W38105
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))
BDBM50554677
PNG
(CHEMBL4765111)
Show SMILES O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]\c2cn(-[#6]-[#6]-[#7]-3-[#6]-[#6]-[#8]-[#6]-[#6]-3)nc2-c2ccccc2)-[#6](=O)-[#7]-1
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n/an/a 7.10E+4n/an/an/an/an/an/a


TBA

Assay Description
Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01451
BindingDB Entry DOI: 10.7270/Q2W38105
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50556314
PNG
(CHEMBL4782569)
Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c3)ccc12
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n/an/a>1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112756
BindingDB Entry DOI: 10.7270/Q2BP06GC
More data for this
Ligand-Target Pair