Found 33 hits with Last Name = 'eunkyeong kim' and Initial = 'e' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50085415
![PNG](/data/jpeg/tenK5008/BindingDB_50085415.png) (3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)Show InChI InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)/b10-3- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50085415
![PNG](/data/jpeg/tenK5008/BindingDB_50085415.png) (3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)Show InChI InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)/b10-3- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50085415
![PNG](/data/jpeg/tenK5008/BindingDB_50085415.png) (3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)Show InChI InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)/b10-3- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50556317
![PNG](/data/jpeg/tenK5055/BindingDB_50556317.png) (CHEMBL4795732)Show SMILES CCN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3c(OC)cccc3n2)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 229 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50554673
![PNG](/data/jpeg/tenK5055/BindingDB_50554673.png) (CHEMBL4760204)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(N)=O |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 |
More data for this Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50556315
![PNG](/data/jpeg/tenK5055/BindingDB_50556315.png) (CHEMBL4745330)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50556319
![PNG](/data/jpeg/tenK5055/BindingDB_50556319.png) (CHEMBL4800457)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)-n4cnc(C)c4)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 414 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Epithelial discoidin domain-containing receptor 1
(Homo sapiens (Human)) | BDBM50556317
![PNG](/data/jpeg/tenK5055/BindingDB_50556317.png) (CHEMBL4795732)Show SMILES CCN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3c(OC)cccc3n2)c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 538 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human DDR1 using KKSRGDYMTMQIG as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50556318
![PNG](/data/jpeg/tenK5055/BindingDB_50556318.png) (CHEMBL4781021)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)N4CCOCC4)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 616 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556317
![PNG](/data/jpeg/tenK5055/BindingDB_50556317.png) (CHEMBL4795732)Show SMILES CCN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3c(OC)cccc3n2)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 888 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556319
![PNG](/data/jpeg/tenK5055/BindingDB_50556319.png) (CHEMBL4800457)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)-n4cnc(C)c4)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50556316
![PNG](/data/jpeg/tenK5055/BindingDB_50556316.png) (CHEMBL4743339)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCOCC5)c(c4)C(F)(F)F)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556315
![PNG](/data/jpeg/tenK5055/BindingDB_50556315.png) (CHEMBL4745330)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556318
![PNG](/data/jpeg/tenK5055/BindingDB_50556318.png) (CHEMBL4781021)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)N4CCOCC4)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50556317
![PNG](/data/jpeg/tenK5055/BindingDB_50556317.png) (CHEMBL4795732)Show SMILES CCN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3c(OC)cccc3n2)c1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human TRKA using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM2579
![PNG](/data/jpeg/tenK0/BindingDB_2579.png) ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human TRKA using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556317
![PNG](/data/jpeg/tenK5055/BindingDB_50556317.png) (CHEMBL4795732)Show SMILES CCN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3c(OC)cccc3n2)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Epithelial discoidin domain-containing receptor 1
(Homo sapiens (Human)) | BDBM50556315
![PNG](/data/jpeg/tenK5055/BindingDB_50556315.png) (CHEMBL4745330)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human DDR1 using KKSRGDYMTMQIG as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Epithelial discoidin domain-containing receptor 1
(Homo sapiens (Human)) | BDBM2579
![PNG](/data/jpeg/tenK0/BindingDB_2579.png) ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human DDR1 using KKSRGDYMTMQIG as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556315
![PNG](/data/jpeg/tenK5055/BindingDB_50556315.png) (CHEMBL4745330)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556316
![PNG](/data/jpeg/tenK5055/BindingDB_50556316.png) (CHEMBL4743339)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCOCC5)c(c4)C(F)(F)F)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50556314
![PNG](/data/jpeg/tenK5055/BindingDB_50556314.png) (CHEMBL4782569)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556318
![PNG](/data/jpeg/tenK5055/BindingDB_50556318.png) (CHEMBL4781021)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)N4CCOCC4)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556319
![PNG](/data/jpeg/tenK5055/BindingDB_50556319.png) (CHEMBL4800457)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)-n4cnc(C)c4)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556314
![PNG](/data/jpeg/tenK5055/BindingDB_50556314.png) (CHEMBL4782569)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50554676
![PNG](/data/jpeg/tenK5055/BindingDB_50554676.png) (CHEMBL4788427)Show SMILES [#6]-[#7]-c1ccc(cc1)-[#6](=O)-[#7]-[#6]-[#6]-n1cc(\[#6]=[#6]-2\[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]-2=O)c(n1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50554672
![PNG](/data/jpeg/tenK5055/BindingDB_50554672.png) (CHEMBL4758139)Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@@H]1C(=O)N[C@@H]([C@@H](C)O)C(O)=O |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50554674
![PNG](/data/jpeg/tenK5055/BindingDB_50554674.png) (CHEMBL4777323)Show SMILES O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]/c2cn(nc2-c2ccccc2)-c2ccccc2)-[#6](=O)-[#7]-1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50556315
![PNG](/data/jpeg/tenK5055/BindingDB_50556315.png) (CHEMBL4745330)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human TRKA using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556316
![PNG](/data/jpeg/tenK5055/BindingDB_50556316.png) (CHEMBL4743339)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCOCC5)c(c4)C(F)(F)F)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50554675
![PNG](/data/jpeg/tenK5055/BindingDB_50554675.png) (CHEMBL4792348)Show SMILES O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]/c2cn(-[#6]-c3ccccc3)nc2-c2ccccc2)-[#6](=O)-[#7]-1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50554677
![PNG](/data/jpeg/tenK5055/BindingDB_50554677.png) (CHEMBL4765111)Show SMILES O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]\c2cn(-[#6]-[#6]-[#7]-3-[#6]-[#6]-[#8]-[#6]-[#6]-3)nc2-c2ccccc2)-[#6](=O)-[#7]-1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50556314
![PNG](/data/jpeg/tenK5055/BindingDB_50556314.png) (CHEMBL4782569)Show SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c3)ccc12 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112756 BindingDB Entry DOI: 10.7270/Q2BP06GC |
More data for this Ligand-Target Pair | |