Compile Data Set for Download or QSAR

Found 52 hits with Last Name = 'kikuchi' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560445 (CHEMBL4792789) Show SMILES Oc1cccc(C(=O)Nc2ccc(Oc3ccc4ccccc4c3Br)c(Cl)c2)c1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560439 (CHEMBL4762099) Show SMILES Oc1ccc(cc1C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1)[N+]([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560448 (CHEMBL4759888) Show SMILES Oc1cccc(O)c1C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560415 (CHEMBL4797256) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560424 (CHEMBL4751500) Show SMILES Oc1cc(O)cc(Oc2ccc(NC(=O)c3cc(Cl)cc(Cl)c3O)cc2Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560420 (CHEMBL4759820) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2cccc(c2)C(F)(F)F)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560419 (CHEMBL4753158) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2ccccc2C(F)(F)F)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560417 (CHEMBL4750439) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2ccc(Cl)cc2Cl)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560428 (CHEMBL4783530) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2ccccc2)cc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560430 (CHEMBL4758154) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2ccccc2)c(Br)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560429 (CHEMBL4747390) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1cc(Cl)c(Oc2ccccc2)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560421 (CHEMBL4793138) Show SMILES Oc1ccccc1Oc1ccc(NC(=O)c2cc(Cl)cc(Cl)c2O)cc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560437 (CHEMBL4748104) Show SMILES Oc1ccc(cc1)C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560433 (CHEMBL4744527) Show SMILES Oc1cc(Oc2ccccc2)ccc1NC(=O)c1cc(Cl)cc(Cl)c1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560438 (CHEMBL4795291) Show SMILES Oc1cc(ccc1C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1)C(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560432 (CHEMBL4757952) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2ccccc2)c(c1)C(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267911 (CHEMBL4096245) Show SMILES Nc1c2ccc(NC(=O)Nc3ccc(cc3)C#N)cc2nc2ccc(O)cc12 Show InChI InChI=1S/C21H15N5O2/c22-11-12-1-3-13(4-2-12)24-21(28)25-14-5-7-16-19(9-14)26-18-8-6-15(27)10-17(18)20(16)23/h1-10,27H,(H2,23,26)(H2,24,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267897 (CHEMBL4092297) Show SMILES CCOc1ccc2nc3cc(NC(=O)c4cccc(c4)C#N)ccc3c(N)c2c1 Show InChI InChI=1S/C23H18N4O2/c1-2-29-17-7-9-20-19(12-17)22(25)18-8-6-16(11-21(18)27-20)26-23(28)15-5-3-4-14(10-15)13-24/h3-12H,2H2,1H3,(H2,25,27)(H,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560418 (CHEMBL4748683) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2cc(Cl)cc(Cl)c2)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560426 (CHEMBL4757062) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2ccc3CCCCc3c2)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560444 (CHEMBL4796271) Show SMILES COc1cccc(OC)c1C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560422 (CHEMBL4762871) Show SMILES Oc1cccc(Oc2ccc(NC(=O)c3cc(Cl)cc(Cl)c3O)cc2Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267896 (CHEMBL4064614) Show SMILES CCOc1ccc2nc3cc(NC(=O)c4cccc(c4)[N+]([O-])=O)ccc3c(N)c2c1 Show InChI InChI=1S/C22H18N4O4/c1-2-30-16-7-9-19-18(12-16)21(23)17-8-6-14(11-20(17)25-19)24-22(27)13-4-3-5-15(10-13)26(28)29/h3-12H,2H2,1H3,(H2,23,25)(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560440 (CHEMBL4783506) Show SMILES Cc1ccc(cc1O)C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50350105 (CHEMBL1814047) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2ccccc2)c(Cl)c1 Show InChI InChI=1S/C19H12Cl3NO3/c20-11-8-14(18(24)16(22)9-11)19(25)23-12-6-7-17(15(21)10-12)26-13-4-2-1-3-5-13/h1-10,24H,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267893 (CHEMBL4086083) Show SMILES COc1ccc2nc3cc(NC(=O)Nc4ccc(cc4)C#N)ccc3c(N)c2c1 Show InChI InChI=1S/C22H17N5O2/c1-29-16-7-9-19-18(11-16)21(24)17-8-6-15(10-20(17)27-19)26-22(28)25-14-4-2-13(12-23)3-5-14/h2-11H,1H3,(H2,24,27)(H2,25,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560416 (CHEMBL4641560) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2ccc(Cl)cc2)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560425 (CHEMBL4796688) Show SMILES Oc1ccc2ccc(Oc3ccc(NC(=O)c4cc(Cl)cc(Cl)c4O)cc3Cl)cc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560423 (CHEMBL4793886) Show SMILES Oc1ccc(Oc2ccc(NC(=O)c3cc(Cl)cc(Cl)c3O)cc2Cl)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560427 (CHEMBL4758811) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267909 (CHEMBL4094766) Show SMILES CCOc1ccc2nc3cc(NC(=O)c4ccc(cc4)C#N)ccc3c(N)c2c1 Show InChI InChI=1S/C23H18N4O2/c1-2-29-17-8-10-20-19(12-17)22(25)18-9-7-16(11-21(18)27-20)26-23(28)15-5-3-14(13-24)4-6-15/h3-12H,2H2,1H3,(H2,25,27)(H,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267895 (CHEMBL4084562) Show SMILES CCOc1ccc2nc3cc(NC(=O)c4ccc5ccccc5c4)ccc3c(N)c2c1 Show InChI InChI=1S/C26H21N3O2/c1-2-31-20-10-12-23-22(15-20)25(27)21-11-9-19(14-24(21)29-23)28-26(30)18-8-7-16-5-3-4-6-17(16)13-18/h3-15H,2H2,1H3,(H2,27,29)(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267916 (CHEMBL531227 | TCMDC-125004) Show SMILES CCOc1ccc2nc3cc(NC(=O)c4ccco4)ccc3c(N)c2c1 Show InChI InChI=1S/C20H17N3O3/c1-2-25-13-6-8-16-15(11-13)19(21)14-7-5-12(10-17(14)23-16)22-20(24)18-4-3-9-26-18/h3-11H,2H2,1H3,(H2,21,23)(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267913 (CHEMBL602783 | GNF-Pf-3043) Show SMILES CCOc1ccc2nc3cc(NCc4ccco4)ccc3c(N)c2c1 Show InChI InChI=1S/C20H19N3O2/c1-2-24-14-6-8-18-17(11-14)20(21)16-7-5-13(10-19(16)23-18)22-12-15-4-3-9-25-15/h3-11,22H,2,12H2,1H3,(H2,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560431 (CHEMBL4781027) Show SMILES Cc1cc(NC(=O)c2cc(Cl)cc(Cl)c2O)ccc1Oc1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267901 (CHEMBL4087066) Show SMILES CCOc1ccc2nc3cc(NC(=O)c4ccc(cc4)[N+]([O-])=O)ccc3c(N)c2c1 Show InChI InChI=1S/C22H18N4O4/c1-2-30-16-8-10-19-18(12-16)21(23)17-9-5-14(11-20(17)25-19)24-22(27)13-3-6-15(7-4-13)26(28)29/h3-12H,2H2,1H3,(H2,23,25)(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267917 (CHEMBL4080499) Show SMILES CCOc1ccc2nc3cc(NCc4ccc(OC)cc4OC)ccc3c(N)c2c1 Show InChI InChI=1S/C24H25N3O3/c1-4-30-18-8-10-21-20(12-18)24(25)19-9-6-16(11-22(19)27-21)26-14-15-5-7-17(28-2)13-23(15)29-3/h5-13,26H,4,14H2,1-3H3,(H2,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267915 (CHEMBL4088361) Show SMILES CCOc1ccc2nc3cc(NC(=O)c4ccccc4)ccc3c(N)c2c1 Show InChI InChI=1S/C22H19N3O2/c1-2-27-16-9-11-19-18(13-16)21(23)17-10-8-15(12-20(17)25-19)24-22(26)14-6-4-3-5-7-14/h3-13H,2H2,1H3,(H2,23,25)(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267921 (CHEMBL4095711) Show SMILES CCOc1ccc2nc3cc(NCc4ccccc4)ccc3c(N)c2c1 Show InChI InChI=1S/C22H21N3O/c1-2-26-17-9-11-20-19(13-17)22(23)18-10-8-16(12-21(18)25-20)24-14-15-6-4-3-5-7-15/h3-13,24H,2,14H2,1H3,(H2,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267910 (CHEMBL4074261) Show SMILES CCOc1ccc2nc3cc(NC(=O)c4ccc(F)cc4)ccc3c(N)c2c1 Show InChI InChI=1S/C22H18FN3O2/c1-2-28-16-8-10-19-18(12-16)21(24)17-9-7-15(11-20(17)26-19)25-22(27)13-3-5-14(23)6-4-13/h3-12H,2H2,1H3,(H2,24,26)(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267914 (CHEMBL4067097) Show SMILES CCOc1ccc2nc3cc(NC(=O)c4ccc(Cl)cc4)ccc3c(N)c2c1 Show InChI InChI=1S/C22H18ClN3O2/c1-2-28-16-8-10-19-18(12-16)21(24)17-9-7-15(11-20(17)26-19)25-22(27)13-3-5-14(23)6-4-13/h3-12H,2H2,1H3,(H2,24,26)(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560434 (CHEMBL4744081) Show SMILES Clc1cc(NC(=O)c2ccccc2)ccc1Oc1ccc2ccccc2c1Br Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560441 (CHEMBL4797907) Show SMILES COc1cccc(C(=O)Nc2ccc(Oc3ccc4ccccc4c3Br)c(Cl)c2)c1OC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560436 (CHEMBL4751625) Show SMILES Oc1cccc(c1)C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560443 (CHEMBL4753349) Show SMILES COc1cc(OC)cc(c1)C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560447 (CHEMBL4745477) Show SMILES Oc1cc(O)cc(c1)C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560446 (CHEMBL4759749) Show SMILES Oc1ccc(cc1O)C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560449 (CHEMBL4749571) Show SMILES Oc1ncccc1C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560435 (CHEMBL4743960) Show SMILES Oc1ccccc1C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560442 (CHEMBL4778943) Show SMILES COc1ccc(cc1OC)C(=O)Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
					More data for this Ligand-Target Pair

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