Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50236004 (CHEMBL4101809) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FORUM Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of CYP2D6 (unknown origin) | J Med Chem 60: 2383-2400 (2017) Article DOI: 10.1021/acs.jmedchem.6b01620 BindingDB Entry DOI: 10.7270/Q2WD42TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C8 (Homo sapiens (Human)) | BDBM50577525 (CHEMBL4848062) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CYP2C8 (unknown origin) | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50236004 (CHEMBL4101809) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FORUM Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of CYP1A2 (unknown origin) | J Med Chem 60: 2383-2400 (2017) Article DOI: 10.1021/acs.jmedchem.6b01620 BindingDB Entry DOI: 10.7270/Q2WD42TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50577525 (CHEMBL4848062) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CYP2D6 (unknown origin) | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50236004 (CHEMBL4101809) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FORUM Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of CYP2C9 (unknown origin) | J Med Chem 60: 2383-2400 (2017) Article DOI: 10.1021/acs.jmedchem.6b01620 BindingDB Entry DOI: 10.7270/Q2WD42TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50577525 (CHEMBL4848062) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CYP2C19 (unknown origin) | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577525 (CHEMBL4848062) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of gamma secretase (unknown origin) assessed as reduction in notch cleavage | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50577525 (CHEMBL4848062) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human ERG | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50236004 (CHEMBL4101809) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FORUM Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of human ERG by patch clamp assay | J Med Chem 60: 2383-2400 (2017) Article DOI: 10.1021/acs.jmedchem.6b01620 BindingDB Entry DOI: 10.7270/Q2WD42TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50236004 (CHEMBL4101809) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FORUM Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of CYP2C19 (unknown origin) | J Med Chem 60: 2383-2400 (2017) Article DOI: 10.1021/acs.jmedchem.6b01620 BindingDB Entry DOI: 10.7270/Q2WD42TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C8 (Homo sapiens (Human)) | BDBM50236004 (CHEMBL4101809) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FORUM Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of CYP2C8 (unknown origin) | J Med Chem 60: 2383-2400 (2017) Article DOI: 10.1021/acs.jmedchem.6b01620 BindingDB Entry DOI: 10.7270/Q2WD42TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50236004 (CHEMBL4101809) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FORUM Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of CYP3A4 (unknown origin) | J Med Chem 60: 2383-2400 (2017) Article DOI: 10.1021/acs.jmedchem.6b01620 BindingDB Entry DOI: 10.7270/Q2WD42TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577496 (CHEMBL4859045) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 97 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577495 (CHEMBL4866858) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 450 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577498 (CHEMBL4846662) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 74 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577499 (CHEMBL4872582) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 39 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577500 (CHEMBL4848262) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577501 (CHEMBL4851690) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577502 (CHEMBL4865043) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 214 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577503 (CHEMBL4878673) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 197 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577504 (CHEMBL4849643) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577505 (CHEMBL4863683) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577506 (CHEMBL4849519) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577507 (CHEMBL4871709) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577508 (CHEMBL4848661) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577509 (CHEMBL4850647) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577510 (CHEMBL4858970) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577511 (CHEMBL4864477) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577512 (CHEMBL4873343) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577513 (CHEMBL4865396) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577514 (CHEMBL4868749) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577515 (CHEMBL4872778) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577516 (CHEMBL4855162) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577517 (CHEMBL4878938) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577518 (CHEMBL4855120) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577519 (CHEMBL4849599) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 75 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577520 (CHEMBL4868827) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577521 (CHEMBL4851284) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577522 (CHEMBL4848087) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577523 (CHEMBL4869387) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577524 (CHEMBL4862666) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577525 (CHEMBL4848062) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577494 (CHEMBL4855113) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577493 (CHEMBL4865935) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 97 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577493 (CHEMBL4865935) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 97 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50236004 (CHEMBL4101809) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50577497 (CHEMBL4855802) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 37 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00904 BindingDB Entry DOI: 10.7270/Q2RV0SJR | |||||||||||
More data for this Ligand-Target Pair |