Compile Data Set for Download or QSAR

Found 74 hits with Last Name = 'lim' and Initial = 'ej'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM15579 (CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r| Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50345949 (3-(4-Methoxy-phenyl)-9-prop-2-ynylamino-3H-pyrido[...) Show SMILES COc1ccc(cc1)-n1cnc2c(sc3nccc(NCC#C)c23)c1=O Show InChI InChI=1S/C19H14N4O2S/c1-3-9-20-14-8-10-21-18-15(14)16-17(26-18)19(24)23(11-22-16)12-4-6-13(25-2)7-5-12/h1,4-8,10-11H,9H2,2H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM86428 (SB-258585) Show SMILES COc1ccc(NS(=O)(=O)c2ccc(I)cc2)cc1N1CCN(C)CC1 Show InChI InChI=1S/C18H22IN3O3S/c1-21-9-11-22(12-10-21)17-13-15(5-8-18(17)25-2)20-26(23,24)16-6-3-14(19)4-7-16/h3-8,13,20H,9-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institutes of Science and Technology (KIST) Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation pretreated for 10 ...				Bioorg Med Chem Lett 23: 4696-700 (2013) Article DOI: 10.1016/j.bmcl.2013.05.100 BindingDB Entry DOI: 10.7270/Q2PZ5CS7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50231755 (6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...) Show SMILES CC1(C)CCc2nc(ccc2C1=O)C#Cc1ccccc1 Show InChI InChI=1S/C19H17NO/c1-19(2)13-12-17-16(18(19)21)11-10-15(20-17)9-8-14-6-4-3-5-7-14/h3-7,10-11H,12-13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Brain Science Institute Curated by ChEMBL					Assay Description Modulation of mGluR5 (unknown origin)				Bioorg Med Chem Lett 23: 1472-6 (2013) Article DOI: 10.1016/j.bmcl.2012.12.056 BindingDB Entry DOI: 10.7270/Q2DR2WVN
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50493222 (CHEMBL2418211) Show SMILES Fc1ccc(cc1)-c1nc2ccc(nc2s1)N1CCCCC1 Show InChI InChI=1S/C17H16FN3S/c18-13-6-4-12(5-7-13)16-19-14-8-9-15(20-17(14)22-16)21-10-2-1-3-11-21/h4-9H,1-3,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058042 (CHEMBL3330823) Show SMILES COc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccccc1C Show InChI InChI=1S/C20H16N2O2S/c1-13-5-3-4-6-16(13)17-11-25-19-18(17)21-12-22(20(19)23)14-7-9-15(24-2)10-8-14/h3-12H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058048 (CHEMBL3330811) Show SMILES COc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C19H14N2O2S/c1-23-15-9-7-14(8-10-15)21-12-20-17-16(11-24-18(17)19(21)22)13-5-3-2-4-6-13/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058044 (CHEMBL3330817) Show SMILES COc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccccc1F Show InChI InChI=1S/C19H13FN2O2S/c1-24-13-8-6-12(7-9-13)22-11-21-17-15(10-25-18(17)19(22)23)14-4-2-3-5-16(14)20/h2-11H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058056 (CHEMBL3330801) Show SMILES Fc1cccc(c1)-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C18H11FN2OS/c19-13-7-4-8-14(9-13)21-11-20-16-15(10-23-17(16)18(21)22)12-5-2-1-3-6-12/h1-11H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058055 (CHEMBL3330802) Show SMILES Fc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C18H11FN2OS/c19-13-6-8-14(9-7-13)21-11-20-16-15(10-23-17(16)18(21)22)12-4-2-1-3-5-12/h1-11H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058047 (CHEMBL3330812 | US9260448, 29) Show SMILES C=Cc1cccc(c1)-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C20H14N2OS/c1-2-14-7-6-10-16(11-14)22-13-21-18-17(12-24-19(18)20(22)23)15-8-4-3-5-9-15/h2-13H,1H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058049 (CHEMBL3330808 | US9260448, 18) Show SMILES Cc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C19H14N2OS/c1-13-7-9-15(10-8-13)21-12-20-17-16(11-23-18(17)19(21)22)14-5-3-2-4-6-14/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058045 (CHEMBL3330813) Show SMILES C=Cc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C20H14N2OS/c1-2-14-8-10-16(11-9-14)22-13-21-18-17(12-24-19(18)20(22)23)15-6-4-3-5-7-15/h2-13H,1H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058059 (CHEMBL3330800) Show SMILES O=c1n(cnc2c(csc12)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H12N2OS/c21-18-17-16(15(11-22-17)13-7-3-1-4-8-13)19-12-20(18)14-9-5-2-6-10-14/h1-12H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058052 (CHEMBL3330805 | US9260448, 7) Show SMILES Clc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C18H11ClN2OS/c19-13-6-8-14(9-7-13)21-11-20-16-15(10-23-17(16)18(21)22)12-4-2-1-3-5-12/h1-11H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50493221 (CHEMBL2418212) Show SMILES Clc1ccccc1-c1nc2ccc(nc2s1)N1CCCCC1 Show InChI InChI=1S/C17H16ClN3S/c18-13-7-3-2-6-12(13)16-19-14-8-9-15(20-17(14)22-16)21-10-4-1-5-11-21/h2-3,6-9H,1,4-5,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058050 (CHEMBL3330807) Show SMILES Cc1cccc(c1)-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C19H14N2OS/c1-13-6-5-9-15(10-13)21-12-20-17-16(11-23-18(17)19(21)22)14-7-3-2-4-8-14/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058043 (CHEMBL3330820) Show SMILES COc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccccc1Cl Show InChI InChI=1S/C19H13ClN2O2S/c1-24-13-8-6-12(7-9-13)22-11-21-17-15(10-25-18(17)19(22)23)14-4-2-3-5-16(14)20/h2-11H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058041 (CHEMBL3330824) Show SMILES COc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1cccc(C)c1 Show InChI InChI=1S/C20H16N2O2S/c1-13-4-3-5-14(10-13)17-11-25-19-18(17)21-12-22(20(19)23)15-6-8-16(24-2)9-7-15/h3-12H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058039 (CHEMBL3330827) Show SMILES COc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1cccc(OC)c1 Show InChI InChI=1S/C20H16N2O3S/c1-24-15-8-6-14(7-9-15)22-12-21-18-17(11-26-19(18)20(22)23)13-4-3-5-16(10-13)25-2/h3-12H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	257	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM251803 (US9469653, 5-39) Show SMILES Clc1ccccc1-c1nc2ccc(nc2o1)N1CCCCC1 Show InChI InChI=1S/C17H16ClN3O/c18-13-7-3-2-6-12(13)16-19-14-8-9-15(20-17(14)22-16)21-10-4-1-5-11-21/h2-3,6-9H,1,4-5,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	267	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM251806 (US9469653, 5-45) Show SMILES Fc1ccc(cc1)-c1nc2ccc(nc2o1)N1CCCCC1 Show InChI InChI=1S/C17H16FN3O/c18-13-6-4-12(5-7-13)16-19-14-8-9-15(20-17(14)22-16)21-10-2-1-3-11-21/h4-9H,1-3,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM251804 (US9469653, 5-40) Show SMILES Fc1cccc(c1)-c1nc2ccc(nc2o1)N1CCCCC1 Show InChI InChI=1S/C17H16FN3O/c18-13-6-4-5-12(11-13)16-19-14-7-8-15(20-17(14)22-16)21-9-2-1-3-10-21/h4-8,11H,1-3,9-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	272	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50492663 (CHEMBL2407553) Show SMILES O=C1N(CC2CCNCC2)CCc2c(NS(=O)(=O)c3cccc4ccccc34)n[nH]c12 Show InChI InChI=1S/C22H25N5O3S/c28-22-20-18(10-13-27(22)14-15-8-11-23-12-9-15)21(25-24-20)26-31(29,30)19-7-3-5-16-4-1-2-6-17(16)19/h1-7,15,23H,8-14H2,(H2,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institutes of Science and Technology (KIST) Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation pretreated for 10 ...				Bioorg Med Chem Lett 23: 4696-700 (2013) Article DOI: 10.1016/j.bmcl.2013.05.100 BindingDB Entry DOI: 10.7270/Q2PZ5CS7
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM251805 (US9469653, 5-41) Show SMILES Clc1cccc(c1)-c1nc2ccc(nc2o1)N1CCCCC1 Show InChI InChI=1S/C17H16ClN3O/c18-13-6-4-5-12(11-13)16-19-14-7-8-15(20-17(14)22-16)21-9-2-1-3-10-21/h4-8,11H,1-3,9-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	335	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM251802 (US9469653, 5-38) Show SMILES C1CCN(CC1)c1ccc2nc(sc2n1)-c1ccccc1 Show InChI InChI=1S/C17H17N3S/c1-3-7-13(8-4-1)16-18-14-9-10-15(19-17(14)21-16)20-11-5-2-6-12-20/h1,3-4,7-10H,2,5-6,11-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50493220 (CHEMBL2418213) Show SMILES Clc1ccc(cc1)-c1nc2ccc(nc2s1)N1CCCCC1 Show InChI InChI=1S/C17H16ClN3S/c18-13-6-4-12(5-7-13)16-19-14-8-9-15(20-17(14)22-16)21-10-2-1-3-11-21/h4-9H,1-3,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	358	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058053 (CHEMBL3330804 | US9260448, 6) Show SMILES Clc1cccc(c1)-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C18H11ClN2OS/c19-13-7-4-8-14(9-13)21-11-20-16-15(10-23-17(16)18(21)22)12-5-2-1-3-6-12/h1-11H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058054 (CHEMBL3330803) Show SMILES Clc1ccccc1-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C18H11ClN2OS/c19-14-8-4-5-9-15(14)21-11-20-16-13(10-23-17(16)18(21)22)12-6-2-1-3-7-12/h1-11H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50429062 (CHEMBL2335279) Show SMILES COc1cccc2nc(ccc12)C#Cc1ccccc1 Show InChI InChI=1S/C18H13NO/c1-20-18-9-5-8-17-16(18)13-12-15(19-17)11-10-14-6-3-2-4-7-14/h2-9,12-13H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Brain Science Institute Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assay				Bioorg Med Chem Lett 23: 1472-6 (2013) Article DOI: 10.1016/j.bmcl.2012.12.056 BindingDB Entry DOI: 10.7270/Q2DR2WVN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50429061 (CHEMBL2335285) Show SMILES COc1cccc2nc(ccc12)C#Cc1cccnc1 Show InChI InChI=1S/C17H12N2O/c1-20-17-6-2-5-16-15(17)10-9-14(19-16)8-7-13-4-3-11-18-12-13/h2-6,9-12H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Brain Science Institute Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assay				Bioorg Med Chem Lett 23: 1472-6 (2013) Article DOI: 10.1016/j.bmcl.2012.12.056 BindingDB Entry DOI: 10.7270/Q2DR2WVN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058051 (CHEMBL3330806) Show SMILES Cc1ccccc1-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C19H14N2OS/c1-13-7-5-6-10-16(13)21-12-20-17-15(11-23-18(17)19(21)22)14-8-3-2-4-9-14/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	499	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50492661 (CHEMBL2407547) Show SMILES COc1ccc(cc1)N1CCc2c(NS(=O)(=O)c3cccc(F)c3)n[nH]c2C1=O Show InChI InChI=1S/C19H17FN4O4S/c1-28-14-7-5-13(6-8-14)24-10-9-16-17(19(24)25)21-22-18(16)23-29(26,27)15-4-2-3-12(20)11-15/h2-8,11H,9-10H2,1H3,(H2,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institutes of Science and Technology (KIST) Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation pretreated for 10 ...				Bioorg Med Chem Lett 23: 4696-700 (2013) Article DOI: 10.1016/j.bmcl.2013.05.100 BindingDB Entry DOI: 10.7270/Q2PZ5CS7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50083571 (CHEMBL3422882) Show SMILES Fc1ccc(cc1)C(=O)N1CCc2c(C1)sc(NCc1ccccc1)c2C#N Show InChI InChI=1S/C22H18FN3OS/c23-17-8-6-16(7-9-17)22(27)26-11-10-18-19(12-24)21(28-20(18)14-26)25-13-15-4-2-1-3-5-15/h1-9,25H,10-11,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 expressed in human Chem-3 cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagen...				Eur J Med Chem 97: 245-58 (2015) Article DOI: 10.1016/j.ejmech.2015.04.060 BindingDB Entry DOI: 10.7270/Q2FJ2JGT
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50493218 (CHEMBL2418204) Show SMILES Fc1ccccc1-c1nc2ccc(nc2o1)N1CCCCC1 Show InChI InChI=1S/C17H16FN3O/c18-13-7-3-2-6-12(13)16-19-14-8-9-15(20-17(14)22-16)21-10-4-1-5-11-21/h2-3,6-9H,1,4-5,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	665	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058057 (CHEMBL3329236 | US9260448, 2) Show SMILES Fc1ccccc1-n1cnc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C18H11FN2OS/c19-14-8-4-5-9-15(14)21-11-20-16-13(10-23-17(16)18(21)22)12-6-2-1-3-7-12/h1-11H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	677	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50058040 (CHEMBL3330826) Show SMILES COc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccccc1OC Show InChI InChI=1S/C20H16N2O3S/c1-24-14-9-7-13(8-10-14)22-12-21-18-16(11-26-19(18)20(22)23)15-5-3-4-6-17(15)25-2/h3-12H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	747	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...				Eur J Med Chem 85: 629-37 (2014) Article DOI: 10.1016/j.ejmech.2014.08.027 BindingDB Entry DOI: 10.7270/Q2B56MDJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50429059 (CHEMBL2335295) Show SMILES Brc1cccc2nc(ccc12)C#Cc1ccccn1 Show InChI InChI=1S/C16H9BrN2/c17-15-5-3-6-16-14(15)10-9-13(19-16)8-7-12-4-1-2-11-18-12/h1-6,9-11H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Brain Science Institute Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assay				Bioorg Med Chem Lett 23: 1472-6 (2013) Article DOI: 10.1016/j.bmcl.2012.12.056 BindingDB Entry DOI: 10.7270/Q2DR2WVN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50492656 (CHEMBL2407551) Show SMILES O=C1N(CCc2c(NS(=O)(=O)c3cccc4ccccc34)n[nH]c12)C1CCNCC1 Show InChI InChI=1S/C21H23N5O3S/c27-21-19-17(10-13-26(21)15-8-11-22-12-9-15)20(24-23-19)25-30(28,29)18-7-3-5-14-4-1-2-6-16(14)18/h1-7,15,22H,8-13H2,(H2,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institutes of Science and Technology (KIST) Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation pretreated for 10 ...				Bioorg Med Chem Lett 23: 4696-700 (2013) Article DOI: 10.1016/j.bmcl.2013.05.100 BindingDB Entry DOI: 10.7270/Q2PZ5CS7
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50493219 (CHEMBL2418209) Show SMILES Clc1ccc(cc1)-c1nc2ccc(nc2o1)N1CCCCC1 Show InChI InChI=1S/C17H16ClN3O/c18-13-6-4-12(5-7-13)16-19-14-8-9-15(20-17(14)22-16)21-10-2-1-3-11-21/h4-9H,1-3,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50429060 (CHEMBL2335291) Show SMILES c1ccc(nc1)C#Cc1ccc2ccccc2n1 Show InChI InChI=1S/C16H10N2/c1-2-7-16-13(5-1)8-9-15(18-16)11-10-14-6-3-4-12-17-14/h1-9,12H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Brain Science Institute Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assay				Bioorg Med Chem Lett 23: 1472-6 (2013) Article DOI: 10.1016/j.bmcl.2012.12.056 BindingDB Entry DOI: 10.7270/Q2DR2WVN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50083626 (CHEMBL3422875) Show SMILES O=C(N1CCc2c(C1)sc(NCc1ccccc1)c2C#N)c1ccn[nH]1 Show InChI InChI=1S/C19H17N5OS/c20-10-15-14-7-9-24(19(25)16-6-8-22-23-16)12-17(14)26-18(15)21-11-13-4-2-1-3-5-13/h1-6,8,21H,7,9,11-12H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 expressed in human Chem-3 cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagen...				Eur J Med Chem 97: 245-58 (2015) Article DOI: 10.1016/j.ejmech.2015.04.060 BindingDB Entry DOI: 10.7270/Q2FJ2JGT
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50083570 (CHEMBL3422883) Show SMILES Fc1ccncc1C(=O)N1CCc2c(C1)sc(NCc1ccccc1)c2C#N Show InChI InChI=1S/C21H17FN4OS/c22-18-6-8-24-12-17(18)21(27)26-9-7-15-16(10-23)20(28-19(15)13-26)25-11-14-4-2-1-3-5-14/h1-6,8,12,25H,7,9,11,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 expressed in human Chem-3 cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagen...				Eur J Med Chem 97: 245-58 (2015) Article DOI: 10.1016/j.ejmech.2015.04.060 BindingDB Entry DOI: 10.7270/Q2FJ2JGT
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM251801 (US9469653, 5-37) Show SMILES C1CCN(CC1)c1ccc2nc(oc2n1)-c1ccccc1 Show InChI InChI=1S/C17H17N3O/c1-3-7-13(8-4-1)16-18-14-9-10-15(19-17(14)21-16)20-11-5-2-6-12-20/h1,3-4,7-10H,2,5-6,11-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using benzylamine hydrochloride as substrate assessed as H2O2 synthesis after 1 hr by fluorescence assay				Bioorg Med Chem 21: 5480-7 (2013) Article DOI: 10.1016/j.bmc.2013.05.066 BindingDB Entry DOI: 10.7270/Q2QN69PN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50083627 (CHEMBL3422874) Show SMILES Cc1cc([nH]n1)C(=O)N1CCc2c(C1)sc(NCc1ccccc1)c2C#N Show InChI InChI=1S/C20H19N5OS/c1-13-9-17(24-23-13)20(26)25-8-7-15-16(10-21)19(27-18(15)12-25)22-11-14-5-3-2-4-6-14/h2-6,9,22H,7-8,11-12H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 expressed in human Chem-3 cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagen...				Eur J Med Chem 97: 245-58 (2015) Article DOI: 10.1016/j.ejmech.2015.04.060 BindingDB Entry DOI: 10.7270/Q2FJ2JGT
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50083632 (CHEMBL3422890) Show SMILES COc1ccc(cc1)C(=O)N1CCc2c(C1)sc(NCc1ccc(F)cc1)c2C#N Show InChI InChI=1S/C23H20FN3O2S/c1-29-18-8-4-16(5-9-18)23(28)27-11-10-19-20(12-25)22(30-21(19)14-27)26-13-15-2-6-17(24)7-3-15/h2-9,26H,10-11,13-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in human embryonic kidney cells assessed as inhibition of L-glutamate-induced calcium release by calciu...				Eur J Med Chem 97: 245-58 (2015) Article DOI: 10.1016/j.ejmech.2015.04.060 BindingDB Entry DOI: 10.7270/Q2FJ2JGT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50492658 (CHEMBL2407545) Show SMILES Cc1ccc(cc1)N1CCc2c(NS(=O)(=O)c3cccc(Cl)c3C)n[nH]c2C1=O Show InChI InChI=1S/C20H19ClN4O3S/c1-12-6-8-14(9-7-12)25-11-10-15-18(20(25)26)22-23-19(15)24-29(27,28)17-5-3-4-16(21)13(17)2/h3-9H,10-11H2,1-2H3,(H2,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institutes of Science and Technology (KIST) Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation pretreated for 10 ...				Bioorg Med Chem Lett 23: 4696-700 (2013) Article DOI: 10.1016/j.bmcl.2013.05.100 BindingDB Entry DOI: 10.7270/Q2PZ5CS7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50083566 (CHEMBL3422887) Show SMILES Fc1ccc(CNc2sc3CN(CCc3c2C#N)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C22H18FN3OS/c23-17-8-6-15(7-9-17)13-25-21-19(12-24)18-10-11-26(14-20(18)28-21)22(27)16-4-2-1-3-5-16/h1-9,25H,10-11,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 expressed in human Chem-3 cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagen...				Eur J Med Chem 97: 245-58 (2015) Article DOI: 10.1016/j.ejmech.2015.04.060 BindingDB Entry DOI: 10.7270/Q2FJ2JGT
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50083574 (CHEMBL3422878) Show SMILES Fc1ccc(CNc2sc3CN(CCc3c2C#N)C(=O)c2ccn[nH]2)cc1 Show InChI InChI=1S/C19H16FN5OS/c20-13-3-1-12(2-4-13)10-22-18-15(9-21)14-6-8-25(11-17(14)27-18)19(26)16-5-7-23-24-16/h1-5,7,22H,6,8,10-11H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 expressed in human Chem-3 cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagen...				Eur J Med Chem 97: 245-58 (2015) Article DOI: 10.1016/j.ejmech.2015.04.060 BindingDB Entry DOI: 10.7270/Q2FJ2JGT
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50083564 (CHEMBL3422892) Show SMILES Fc1ccc(cc1)C(=O)N1CCc2c(C1)sc(NCc1cccc(F)c1)c2C#N Show InChI InChI=1S/C22H17F2N3OS/c23-16-6-4-15(5-7-16)22(28)27-9-8-18-19(11-25)21(29-20(18)13-27)26-12-14-2-1-3-17(24)10-14/h1-7,10,26H,8-9,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 expressed in human Chem-3 cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagen...				Eur J Med Chem 97: 245-58 (2015) Article DOI: 10.1016/j.ejmech.2015.04.060 BindingDB Entry DOI: 10.7270/Q2FJ2JGT
					More data for this Ligand-Target Pair

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