Compile Data Set for Download or QSAR

Found 12 hits with Last Name = 'matera' and Initial = 'el'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50193013 (Duvelisib | INK-1147 | INK-1197 | IPI-145) Show SMILES C[C@H](Nc1ncnc2nc[nH]c12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCdelta/PIK3R1 (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50193013 (Duvelisib | INK-1147 | INK-1197 | IPI-145) Show SMILES C[C@H](Nc1ncnc2nc[nH]c12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCgamma (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50403068 (CHEMBL2216870 | IDELALISIB | US9745321, CAL-101) Show SMILES CC[C@H](Nc1ncnc2nc[nH]c12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCdelta/PIK3R1 (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50193013 (Duvelisib | INK-1147 | INK-1197 | IPI-145) Show SMILES C[C@H](Nc1ncnc2nc[nH]c12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCbeta/PIK3R1 (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50403068 (CHEMBL2216870 | IDELALISIB | US9745321, CAL-101) Show SMILES CC[C@H](Nc1ncnc2nc[nH]c12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCgamma (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50193013 (Duvelisib | INK-1147 | INK-1197 | IPI-145) Show SMILES C[C@H](Nc1ncnc2nc[nH]c12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCalpha/PIK3R1 (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50403068 (CHEMBL2216870 | IDELALISIB | US9745321, CAL-101) Show SMILES CC[C@H](Nc1ncnc2nc[nH]c12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCbeta/PIK3R1 (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50403068 (CHEMBL2216870 | IDELALISIB | US9745321, CAL-101) Show SMILES CC[C@H](Nc1ncnc2nc[nH]c12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCalpha/PIK3R1 (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50467362 (CHEMBL4287949) Show SMILES COc1cc(OC)c(\C=C\C(=O)c2c(OC)cc(OC)c(C3CCN(C)CC3)c2O)c(OC)c1 Show InChI InChI=1S/C26H33NO7/c1-27-11-9-16(10-12-27)24-22(33-5)15-23(34-6)25(26(24)29)19(28)8-7-18-20(31-3)13-17(30-2)14-21(18)32-4/h7-8,13-16,29H,9-12H2,1-6H3/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCdelta/PIK3R1 (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50467362 (CHEMBL4287949) Show SMILES COc1cc(OC)c(\C=C\C(=O)c2c(OC)cc(OC)c(C3CCN(C)CC3)c2O)c(OC)c1 Show InChI InChI=1S/C26H33NO7/c1-27-11-9-16(10-12-27)24-22(33-5)15-23(34-6)25(26(24)29)19(28)8-7-18-20(31-3)13-17(30-2)14-21(18)32-4/h7-8,13-16,29H,9-12H2,1-6H3/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCgamma (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50467362 (CHEMBL4287949) Show SMILES COc1cc(OC)c(\C=C\C(=O)c2c(OC)cc(OC)c(C3CCN(C)CC3)c2O)c(OC)c1 Show InChI InChI=1S/C26H33NO7/c1-27-11-9-16(10-12-27)24-22(33-5)15-23(34-6)25(26(24)29)19(28)8-7-18-20(31-3)13-17(30-2)14-21(18)32-4/h7-8,13-16,29H,9-12H2,1-6H3/b8-7+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCalpha/PIK3R1 (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50467362 (CHEMBL4287949) Show SMILES COc1cc(OC)c(\C=C\C(=O)c2c(OC)cc(OC)c(C3CCN(C)CC3)c2O)c(OC)c1 Show InChI InChI=1S/C26H33NO7/c1-27-11-9-16(10-12-27)24-22(33-5)15-23(34-6)25(26(24)29)19(28)8-7-18-20(31-3)13-17(30-2)14-21(18)32-4/h7-8,13-16,29H,9-12H2,1-6H3/b8-7+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCbeta/PIK3R1 (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
					More data for this Ligand-Target Pair