Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552588 (N-[2-({4-[3-(3-chloro-2-methoxyanilino)-4-oxo-4,5,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552593 (N-[2-({4-[3-(3-fluoro-2-methoxyanilino)-4-oxo-4,5,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552600 (3-(3-chloro-2-methoxyanilino)-2-(3-{[(2S)-1-(prop-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552592 (N-[2-({4-[3-(3-chloro-2-methoxyanilino)-4-oxo-4,5,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552590 (N-[2-({4-[3-(3-chloro-2-methylanilino)-4-oxo-4,5,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552591 (N-[3-({4-[3-(3-chloro-2-methoxyanilino)-4-oxo-4,5,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552589 (N-[2-({4-[3-(3-fluoro-2-methylanilino)-4-oxo-4,5,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552598 (N-[2-({4-[3'-(3-chloro-2-methoxyanilino)-4'-oxo-1'...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552595 ((2E)-4-(dimethylamino)-N-[2-({4-[3-(3-fluoro-2-met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552601 (N-(2-{[4-(3-{[2-(difluoromethoxy)phenyl]amino}-4-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552599 (N-[2-({4-[3-(3-chloro-2-methoxyanilino)-6,6-dimeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552594 (N-[2-({4-[3-(4-fluoroanilino)-4-oxo-4,5,6,7-tetrah...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 1.62 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552596 ((2E)-N-[2-({4-[3-(3-chloro-2-methoxyanilino)-4-oxo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 2.48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM552597 ((2E)-N-[2-({4-[3'-(3-chloro-2-methoxyanilino)-4'-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022101184 | n/a | n/a | 3.55 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542RSQ | |||||||||||
More data for this Ligand-Target Pair |