Compile Data Set for Download or QSAR

Found 45 hits with Last Name = 'hockerman' and Initial = 'gh'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM24182 (4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...) Show SMILES NCC(CC(O)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assay				J Med Chem 58: 6336-47 (2015) Article DOI: 10.1021/jm5018913 BindingDB Entry DOI: 10.7270/Q2T155F6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50007119 (4-Amino-3-phenyl-butyric acid | CHEMBL53073) Show SMILES NC[C@H](CC(O)=O)c1ccccc1 Show InChI InChI=1S/C10H13NO2/c11-7-9(6-10(12)13)8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)/t9-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assay				J Med Chem 58: 6336-47 (2015) Article DOI: 10.1021/jm5018913 BindingDB Entry DOI: 10.7270/Q2T155F6
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50007119 (4-Amino-3-phenyl-butyric acid | CHEMBL53073) Show SMILES NC[C@H](CC(O)=O)c1ccccc1 Show InChI InChI=1S/C10H13NO2/c11-7-9(6-10(12)13)8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)/t9-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.77E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assay				J Med Chem 58: 6336-47 (2015) Article DOI: 10.1021/jm5018913 BindingDB Entry DOI: 10.7270/Q2T155F6
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50007118 (4-Amino-3-(5-chloro-thiophen-2-yl)-butyric acid | ...) Show SMILES NCC(CC(O)=O)c1ccc(Cl)s1 Show InChI InChI=1S/C8H10ClNO2S/c9-7-2-1-6(13-7)5(4-10)3-8(11)12/h1-2,5H,3-4,10H2,(H,11,12)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to GABA-B receptor (unknown origin)				J Med Chem 58: 6336-47 (2015) Article DOI: 10.1021/jm5018913 BindingDB Entry DOI: 10.7270/Q2T155F6
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427602 (CHEMBL2322937) Show SMILES COC(c1ccc(cc1)C(C)=O)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |THB:22:21:18:24.23.25,22:23:20.21.26:18,25:23:20:26.17.18,25:17:20:24.22.23,15:17:20:24.22.23| Show InChI InChI=1S/C22H26F2O3/c1-13(25)17-3-5-18(6-4-17)19(27-2)22(23,24)20(26)21-10-14-7-15(11-21)9-16(8-14)12-21/h3-6,14-16,19H,7-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427603 (CHEMBL2322934) Show SMILES CC(=O)c1ccc(cc1)C(O)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |THB:21:20:17:23.22.24,21:22:19.20.25:17,24:22:19:25.16.17,24:16:19:23.21.22,14:16:19:23.21.22| Show InChI InChI=1S/C21H24F2O3/c1-12(24)16-2-4-17(5-3-16)18(25)21(22,23)19(26)20-9-13-6-14(10-20)8-15(7-13)11-20/h2-5,13-15,18,25H,6-11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.78E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427603 (CHEMBL2322934) Show SMILES CC(=O)c1ccc(cc1)C(O)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |THB:21:20:17:23.22.24,21:22:19.20.25:17,24:22:19:25.16.17,24:16:19:23.21.22,14:16:19:23.21.22| Show InChI InChI=1S/C21H24F2O3/c1-12(24)16-2-4-17(5-3-16)18(25)21(22,23)19(26)20-9-13-6-14(10-20)8-15(7-13)11-20/h2-5,13-15,18,25H,6-11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.78E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50032964 ((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...) Show SMILES NC[C@H](CC(O)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)/t8-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427604 (CHEMBL2322936) Show SMILES FC(F)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C12H8F2O/c13-12(14)11(15)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,12H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427605 (CHEMBL2322932) Show SMILES C[C@H](C[C@@H](O)C(F)(F)C(=O)c1ccc2OCOc2c1)O[Si](C(C)C)(C(C)C)C(C)C |r| Show InChI InChI=1S/C22H34F2O5Si/c1-13(2)30(14(3)4,15(5)6)29-16(7)10-20(25)22(23,24)21(26)17-8-9-18-19(11-17)28-12-27-18/h8-9,11,13-16,20,25H,10,12H2,1-7H3/t16-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427606 (CHEMBL2322945) Show SMILES C\C=C\C=C\C(O)C(F)(F)C(=O)C(C)(C)C Show InChI InChI=1S/C12H18F2O2/c1-5-6-7-8-9(15)12(13,14)10(16)11(2,3)4/h5-9,15H,1-4H3/b6-5+,8-7+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427607 (CHEMBL2322944) Show SMILES CCCCC=CC(=O)C(F)(F)C(O)\C=C\C=C\C |w:4.3| Show InChI InChI=1S/C14H20F2O2/c1-3-5-7-9-11-13(18)14(15,16)12(17)10-8-6-4-2/h4,6,8-12,17H,3,5,7H2,1-2H3/b6-4+,10-8+,11-9?	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427608 (CHEMBL2322943) Show SMILES CCC\C=C\C(O)C(F)(F)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C14H15ClF2O2/c1-2-3-4-5-12(18)14(16,17)13(19)10-6-8-11(15)9-7-10/h4-9,12,18H,2-3H2,1H3/b5-4+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427609 (CHEMBL2322941) Show SMILES C\C=C\C=C\C(O)C(F)(F)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C18H16F2O2/c1-2-3-4-9-16(21)18(19,20)17(22)15-11-10-13-7-5-6-8-14(13)12-15/h2-12,16,21H,1H3/b3-2+,9-4+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.93E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427610 (CHEMBL2322940) Show SMILES CCC\C=C\C(O)C(F)(F)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C18H18F2O2/c1-2-3-4-9-16(21)18(19,20)17(22)15-11-10-13-7-5-6-8-14(13)12-15/h4-12,16,21H,2-3H2,1H3/b9-4+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.69E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427611 (CHEMBL2322939) Show SMILES COc1ccc(cc1)C(O)C(F)(F)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C20H16F2O3/c1-25-17-10-8-14(9-11-17)18(23)20(21,22)19(24)16-7-6-13-4-2-3-5-15(13)12-16/h2-12,18,23H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.18E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427612 (CHEMBL2322942) Show SMILES OC(C1CCCCC1)C(F)(F)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C19H20F2O2/c20-19(21,17(22)14-7-2-1-3-8-14)18(23)16-11-10-13-6-4-5-9-15(13)12-16/h4-6,9-12,14,17,22H,1-3,7-8H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.35E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427613 (CHEMBL2322935) Show SMILES OC(\C=C\c1ccccc1)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |THB:20:19:16:22.21.23,20:21:18.19.24:16,23:21:18:24.15.16,23:15:18:22.20.21,13:15:18:22.20.21| Show InChI InChI=1S/C21H24F2O2/c22-21(23,18(24)7-6-14-4-2-1-3-5-14)19(25)20-11-15-8-16(12-20)10-17(9-15)13-20/h1-7,15-18,24H,8-13H2/b7-6+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50462450 (CHEMBL4238712) Show SMILES FC(F)(C(NS(=O)(=O)c1ccccc1)c1ccccc1)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C25H19F2NO3S/c26-25(27,24(29)21-16-15-18-9-7-8-12-20(18)17-21)23(19-10-3-1-4-11-19)28-32(30,31)22-13-5-2-6-14-22/h1-17,23,28H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at rat GFP-fused GABA-A alpha1/beta2/gamma2 receptor expressed in human tsA201 cells at -60 mV holding potential by whole-cell volta...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427614 (CHEMBL2322946) Show SMILES CC(C)(C)c1cc2c(OC(=O)C2(O)C(F)(F)F)c(c1)C(C)(C)C Show InChI InChI=1S/C17H21F3O3/c1-14(2,3)9-7-10(15(4,5)6)12-11(8-9)16(22,13(21)23-12)17(18,19)20/h7-8,22H,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM24182 (4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...) Show SMILES NCC(CC(O)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462442 (CHEMBL4245403) Show SMILES CC(C)CC(=O)C(F)(F)C(NC(=O)OC(C)(C)C)c1ccccc1 Show InChI InChI=1S/C18H25F2NO3/c1-12(2)11-14(22)18(19,20)15(13-9-7-6-8-10-13)21-16(23)24-17(3,4)5/h6-10,12,15H,11H2,1-5H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50427613 (CHEMBL2322935) Show SMILES OC(\C=C\c1ccccc1)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |THB:20:19:16:22.21.23,20:21:18.19.24:16,23:21:18:24.15.16,23:15:18:22.20.21,13:15:18:22.20.21| Show InChI InChI=1S/C21H24F2O2/c22-21(23,18(24)7-6-14-4-2-1-3-5-14)19(25)20-11-15-8-16(12-20)10-17(9-15)13-20/h1-7,15-18,24H,8-13H2/b7-6+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at rat GFP-fused GABA-A alpha1/beta2/gamma2 receptor expressed in human tsA201 cells at -60 mV holding potential by whole-cell volta...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50462443 (CHEMBL4238315) Show SMILES FC(F)(C(NCc1ccccc1)c1ccccc1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H18ClF2NO/c23-19-13-11-18(12-14-19)21(27)22(24,25)20(17-9-5-2-6-10-17)26-15-16-7-3-1-4-8-16/h1-14,20,26H,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at rat GFP-fused GABA-A alpha1/beta2/gamma2 receptor expressed in human tsA201 cells at -60 mV holding potential by whole-cell volta...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462444 (CHEMBL4244129) Show SMILES FC(F)(C(NCc1ccccc1)c1ccccc1)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C26H21F2NO/c27-26(28,25(30)23-16-15-20-11-7-8-14-22(20)17-23)24(21-12-5-2-6-13-21)29-18-19-9-3-1-4-10-19/h1-17,24,29H,18H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50427613 (CHEMBL2322935) Show SMILES OC(\C=C\c1ccccc1)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |THB:20:19:16:22.21.23,20:21:18.19.24:16,23:21:18:24.15.16,23:15:18:22.20.21,13:15:18:22.20.21| Show InChI InChI=1S/C21H24F2O2/c22-21(23,18(24)7-6-14-4-2-1-3-5-14)19(25)20-11-15-8-16(12-20)10-17(9-15)13-20/h1-7,15-18,24H,8-13H2/b7-6+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462445 (CHEMBL4246158) Show SMILES OC(c1ccc(Cl)cc1)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |TLB:12:14:17:21.19.20,THB:19:18:15:21.20.22,19:20:17.18.23:15,22:20:17:23.14.15,22:14:17:21.19.20| Show InChI InChI=1S/C19H21ClF2O2/c20-15-3-1-14(2-4-15)16(23)19(21,22)17(24)18-8-11-5-12(9-18)7-13(6-11)10-18/h1-4,11-13,16,23H,5-10H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50462444 (CHEMBL4244129) Show SMILES FC(F)(C(NCc1ccccc1)c1ccccc1)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C26H21F2NO/c27-26(28,25(30)23-16-15-20-11-7-8-14-22(20)17-23)24(21-12-5-2-6-13-21)29-18-19-9-3-1-4-10-19/h1-17,24,29H,18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at rat GFP-fused GABA-A alpha1/beta2/gamma2 receptor expressed in human tsA201 cells at -60 mV holding potential by whole-cell volta...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50462446 (CHEMBL4238634) Show SMILES CC(C)(C)OC(=O)NC(c1ccccc1)C(F)(F)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H23F2NO3/c1-23(2,3)30-22(29)27-20(17-10-5-4-6-11-17)24(25,26)21(28)19-14-13-16-9-7-8-12-18(16)15-19/h4-15,20H,1-3H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at rat GFP-fused GABA-A alpha1/beta2/gamma2 receptor expressed in human tsA201 cells at -60 mV holding potential by whole-cell volta...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462447 (CHEMBL4248377) Show SMILES C\C=C\C=C\C(NCc1ccccc1)C(F)(F)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C25H23F2NO/c1-2-3-5-14-23(28-18-19-10-6-4-7-11-19)25(26,27)24(29)22-16-15-20-12-8-9-13-21(20)17-22/h2-17,23,28H,18H2,1H3/b3-2+,14-5+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462448 (CHEMBL4241188) Show SMILES CC(C)(C)OC(=O)NC(c1ccccc1)C(F)(F)C(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C21H21F2NO5/c1-20(2,3)29-19(26)24-17(13-7-5-4-6-8-13)21(22,23)18(25)14-9-10-15-16(11-14)28-12-27-15/h4-11,17H,12H2,1-3H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462449 (CHEMBL4247210) Show SMILES FC(F)(C(NS(=O)(=O)c1ccccc1)c1ccccc1)C(=O)C12CC3CC(CC(C3)C1)C2 |THB:27:26:23:29.28.30,27:28:25.26.31:23,30:28:25:31.22.23,30:22:25:29.27.28| Show InChI InChI=1S/C25H27F2NO3S/c26-25(27,23(29)24-14-17-11-18(15-24)13-19(12-17)16-24)22(20-7-3-1-4-8-20)28-32(30,31)21-9-5-2-6-10-21/h1-10,17-19,22,28H,11-16H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462450 (CHEMBL4238712) Show SMILES FC(F)(C(NS(=O)(=O)c1ccccc1)c1ccccc1)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C25H19F2NO3S/c26-25(27,24(29)21-16-15-18-9-7-8-12-20(18)17-21)23(19-10-3-1-4-11-19)28-32(30,31)22-13-5-2-6-14-22/h1-17,23,28H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.27E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462451 (CHEMBL4249205) Show SMILES OC(CN1C(=O)c2ccccc2C1=O)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |TLB:17:19:22:26.24.25,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| Show InChI InChI=1S/C22H23F2NO4/c23-22(24,20(29)21-8-12-5-13(9-21)7-14(6-12)10-21)17(26)11-25-18(27)15-3-1-2-4-16(15)19(25)28/h1-4,12-14,17,26H,5-11H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462452 (CHEMBL4244940) Show SMILES CC(=O)c1ccc(cc1)C(O)C(F)(F)C(=O)c1ccccn1 Show InChI InChI=1S/C16H13F2NO3/c1-10(20)11-5-7-12(8-6-11)14(21)16(17,18)15(22)13-4-2-3-9-19-13/h2-9,14,21H,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462453 (CHEMBL4244933) Show SMILES OC(c1ccccc1)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |TLB:11:13:16:20.18.19,THB:18:17:14:20.19.21,18:19:16.17.22:14,21:19:16:22.13.14,21:13:16:20.18.19| Show InChI InChI=1S/C19H22F2O2/c20-19(21,16(22)15-4-2-1-3-5-15)17(23)18-9-12-6-13(10-18)8-14(7-12)11-18/h1-5,12-14,16,22H,6-11H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462446 (CHEMBL4238634) Show SMILES CC(C)(C)OC(=O)NC(c1ccccc1)C(F)(F)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H23F2NO3/c1-23(2,3)30-22(29)27-20(17-10-5-4-6-11-17)24(25,26)21(28)19-14-13-16-9-7-8-12-18(16)15-19/h4-15,20H,1-3H3,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.94E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462454 (CHEMBL4250786) Show SMILES CCc1ccc(cc1)C(O)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |TLB:13:15:18:22.20.21,THB:20:19:16:22.21.23,20:21:18.19.24:16,23:21:18:24.15.16,23:15:18:22.20.21| Show InChI InChI=1S/C21H26F2O2/c1-2-13-3-5-17(6-4-13)18(24)21(22,23)19(25)20-10-14-7-15(11-20)9-16(8-14)12-20/h3-6,14-16,18,24H,2,7-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit beta-1/beta-2 (Homo sapiens (Human))	BDBM50462443 (CHEMBL4238315) Show SMILES FC(F)(C(NCc1ccccc1)c1ccccc1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H18ClF2NO/c23-19-13-11-18(12-14-19)21(27)22(24,25)20(17-9-5-2-6-10-17)26-15-16-7-3-1-4-8-16/h1-14,20,26H,15H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.74E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...				Bioorg Med Chem Lett 28: 2697-2700 (2018) Article DOI: 10.1016/j.bmcl.2018.04.003 BindingDB Entry DOI: 10.7270/Q20P12N7
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427601 (CHEMBL2322938) Show SMILES CC(=O)c1ccc(cc1)C(O)CC(=O)C12CC3CC(CC(C3)C1)C2 |THB:19:18:15:21.20.22,19:20:17.18.23:15,22:20:17:23.14.15,22:14:17:21.19.20,12:14:17:21.19.20| Show InChI InChI=1S/C21H26O3/c1-13(22)17-2-4-18(5-3-17)19(23)9-20(24)21-10-14-6-15(11-21)8-16(7-14)12-21/h2-5,14-16,19,23H,6-12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50108998 (CHEMBL3600560) Show SMILES NC[C@@H](F)CP(O)(O)=O |r| Show InChI InChI=1S/C3H9FNO3P/c4-3(1-5)2-9(6,7)8/h3H,1-2,5H2,(H2,6,7,8)/t3-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.60	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human recombinant GABA-B receptor				J Med Chem 58: 6336-47 (2015) Article DOI: 10.1021/jm5018913 BindingDB Entry DOI: 10.7270/Q2T155F6
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50108997 (CGP-71872 | CHEMBL1628548) Show SMILES C[C@@H](NC[C@H](O)CP(O)(=O)CCCCCNC(=O)c1cc([125I])c(cc1O)N=[N+]=[N-])c1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C24H31IN5O7P/c1-15(16-6-5-7-17(10-16)24(34)35)28-13-18(31)14-38(36,37)9-4-2-3-8-27-23(33)19-11-20(25)21(29-30-26)12-22(19)32/h5-7,10-12,15,18,28,31-32H,2-4,8-9,13-14H2,1H3,(H,27,33)(H,34,35)(H,36,37)/t15-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to GABA-B receptor (unknown origin)				J Med Chem 58: 6336-47 (2015) Article DOI: 10.1021/jm5018913 BindingDB Entry DOI: 10.7270/Q2T155F6
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50108996 (CGP-7930 | CHEMBL1256697) Show SMILES CC(C)(CO)Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C19H32O2/c1-17(2,3)14-9-13(11-19(7,8)12-20)10-15(16(14)21)18(4,5)6/h9-10,20-21H,11-12H2,1-8H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.37E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Positive allosteric modulator activity at GABA-B receptor (unknown origin) assessed as potentiation of 1 uM GABA-induced [35S]GTPgammaS binding				J Med Chem 58: 6336-47 (2015) Article DOI: 10.1021/jm5018913 BindingDB Entry DOI: 10.7270/Q2T155F6
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM50427603 (CHEMBL2322934) Show SMILES CC(=O)c1ccc(cc1)C(O)C(F)(F)C(=O)C12CC3CC(CC(C3)C1)C2 |THB:21:20:17:23.22.24,21:22:19.20.25:17,24:22:19:25.16.17,24:16:19:23.21.22,14:16:19:23.21.22| Show InChI InChI=1S/C21H24F2O3/c1-12(24)16-2-4-17(5-3-16)18(25)21(22,23)19(26)20-9-13-6-14(10-20)8-15(7-13)11-20/h2-5,13-15,18,25H,6-11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
					More data for this Ligand-Target Pair