Compile Data Set for Download or QSAR

Found 1206 hits with Last Name = 'peltier' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50323351 (6-[(S)-1-(4-Chloro-phenyl)-ethyl]-4-isobutyl-6,7-d...) Show SMILES CC(C)CC1n2cncc2CN([C@@H](C)c2ccc(Cl)cc2)S1(=O)=O |r| Show InChI InChI=1S/C17H22ClN3O2S/c1-12(2)8-17-20-11-19-9-16(20)10-21(24(17,22)23)13(3)14-4-6-15(18)7-5-14/h4-7,9,11-13,17H,8,10H2,1-3H3/t13-,17?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human CYP11B2				Bioorg Med Chem Lett 23: 5471-83 (2013) Article DOI: 10.1016/j.bmcl.2013.08.003 BindingDB Entry DOI: 10.7270/Q2R49S6F
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50323353 (1-{6-[(S)-1-(4-Chloro-phenyl)-ethyl]-5,5-dioxo-4,5...) Show SMILES C[C@H](N1Cc2cncn2C(CC(C)(C)O)S1(=O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C17H22ClN3O3S/c1-12(13-4-6-14(18)7-5-13)21-10-15-9-19-11-20(15)16(25(21,23)24)8-17(2,3)22/h4-7,9,11-12,16,22H,8,10H2,1-3H3/t12-,16?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human CYP11B2				Bioorg Med Chem Lett 23: 5471-83 (2013) Article DOI: 10.1016/j.bmcl.2013.08.003 BindingDB Entry DOI: 10.7270/Q2R49S6F
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475561 (1-[6-Chloro-5-(4-chloro-phenylmethanesulfonyl)-1H-...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C18H12Cl2N4O4S/c19-12-3-1-10(2-4-12)9-29(27,28)16-6-15-14(5-13(16)20)22-18(23-15)24-8-11(7-21-24)17(25)26/h1-8H,9H2,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475561 (1-[6-Chloro-5-(4-chloro-phenylmethanesulfonyl)-1H-...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C18H12Cl2N4O4S/c19-12-3-1-10(2-4-12)9-29(27,28)16-6-15-14(5-13(16)20)22-18(23-15)24-8-11(7-21-24)17(25)26/h1-8H,9H2,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475567 (1-[6-Chloro-5-(4-trifluoromethyl-phenylmethanesulf...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H12ClF3N4O4S/c20-13-5-14-15(26-18(25-14)27-8-11(7-24-27)17(28)29)6-16(13)32(30,31)9-10-1-3-12(4-2-10)19(21,22)23/h1-8H,9H2,(H,25,26)(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475569 (1-[6-Chloro-5-(2'-cyano-biphenyl-4-ylmethanesulfon...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(cc1)-c1ccccc1C#N Show InChI InChI=1S/C25H16ClN5O4S/c26-20-9-21-22(30-25(29-21)31-13-18(12-28-31)24(32)33)10-23(20)36(34,35)14-15-5-7-16(8-6-15)19-4-2-1-3-17(19)11-27/h1-10,12-13H,14H2,(H,29,30)(H,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475479 (1-[6-Chloro-5-(4-methoxy-phenylmethanesulfonyl)-1H...) Show SMILES COc1ccc(CS(=O)(=O)c2cc3nc([nH]c3cc2Cl)-n2cc(cn2)C(O)=O)cc1 Show InChI InChI=1S/C19H15ClN4O5S/c1-29-13-4-2-11(3-5-13)10-30(27,28)17-7-16-15(6-14(17)20)22-19(23-16)24-9-12(8-21-24)18(25)26/h2-9H,10H2,1H3,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475563 (1-(6-Chloro-5-cyclohexylmethanesulfonyl-1H- | US10...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)CC1CCCCC1 Show InChI InChI=1S/C18H19ClN4O4S/c19-13-6-14-15(22-18(21-14)23-9-12(8-20-23)17(24)25)7-16(13)28(26,27)10-11-4-2-1-3-5-11/h6-9,11H,1-5,10H2,(H,21,22)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475557 (1-[6-Chloro-5-(4-methyl-benzylsulfanyl)-1H- | US10...) Show SMILES Cc1ccc(CS(=O)(=O)c2cc3nc([nH]c3cc2Cl)-n2cc(cn2)C(O)=O)cc1 Show InChI InChI=1S/C19H15ClN4O4S/c1-11-2-4-12(5-3-11)10-29(27,28)17-7-16-15(6-14(17)20)22-19(23-16)24-9-13(8-21-24)18(25)26/h2-9H,10H2,1H3,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475567 (1-[6-Chloro-5-(4-trifluoromethyl-phenylmethanesulf...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H12ClF3N4O4S/c20-13-5-14-15(26-18(25-14)27-8-11(7-24-27)17(28)29)6-16(13)32(30,31)9-10-1-3-12(4-2-10)19(21,22)23/h1-8H,9H2,(H,25,26)(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475569 (1-[6-Chloro-5-(2'-cyano-biphenyl-4-ylmethanesulfon...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(cc1)-c1ccccc1C#N Show InChI InChI=1S/C25H16ClN5O4S/c26-20-9-21-22(30-25(29-21)31-13-18(12-28-31)24(32)33)10-23(20)36(34,35)14-15-5-7-16(8-6-15)19-4-2-1-3-17(19)11-27/h1-10,12-13H,14H2,(H,29,30)(H,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475563 (1-(6-Chloro-5-cyclohexylmethanesulfonyl-1H- | US10...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)CC1CCCCC1 Show InChI InChI=1S/C18H19ClN4O4S/c19-13-6-14-15(22-18(21-14)23-9-12(8-20-23)17(24)25)7-16(13)28(26,27)10-11-4-2-1-3-5-11/h6-9,11H,1-5,10H2,(H,21,22)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475479 (1-[6-Chloro-5-(4-methoxy-phenylmethanesulfonyl)-1H...) Show SMILES COc1ccc(CS(=O)(=O)c2cc3nc([nH]c3cc2Cl)-n2cc(cn2)C(O)=O)cc1 Show InChI InChI=1S/C19H15ClN4O5S/c1-29-13-4-2-11(3-5-13)10-30(27,28)17-7-16-15(6-14(17)20)22-19(23-16)24-9-12(8-21-24)18(25)26/h2-9H,10H2,1H3,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475557 (1-[6-Chloro-5-(4-methyl-benzylsulfanyl)-1H- | US10...) Show SMILES Cc1ccc(CS(=O)(=O)c2cc3nc([nH]c3cc2Cl)-n2cc(cn2)C(O)=O)cc1 Show InChI InChI=1S/C19H15ClN4O4S/c1-11-2-4-12(5-3-11)10-29(27,28)17-7-16-15(6-14(17)20)22-19(23-16)24-9-13(8-21-24)18(25)26/h2-9H,10H2,1H3,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475485 (1-(6-Methanesulfonyl-5-trifluoromethyl-1H- | US108...) Show SMILES CS(=O)(=O)c1cc2[nH]c(nc2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C13H9F3N4O4S/c1-25(23,24)10-3-9-8(2-7(10)13(14,15)16)18-12(19-9)20-5-6(4-17-20)11(21)22/h2-5H,1H3,(H,18,19)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475543 (1-(5-Ethylsulfonyl-6-trifluoromethoxy-1H-benzoimid...) Show SMILES CCS(=O)(=O)c1cc2nc([nH]c2cc1OC(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C14H11F3N4O5S/c1-2-27(24,25)11-4-9-8(3-10(11)26-14(15,16)17)19-13(20-9)21-6-7(5-18-21)12(22)23/h3-6H,2H2,1H3,(H,19,20)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475549 (1-(5-Benzenesulfonyl-6-trifluoromethyl-1H- | US108...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(cc2[nH]1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H11F3N4O4S/c19-18(20,21)12-6-13-14(7-15(12)30(28,29)11-4-2-1-3-5-11)24-17(23-13)25-9-10(8-22-25)16(26)27/h1-9H,(H,23,24)(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475550 (1-[5-(4-Methoxy-benzenesulfonyl)-6-trifluoromethyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1cc2nc([nH]c2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C19H13F3N4O5S/c1-31-11-2-4-12(5-3-11)32(29,30)16-7-15-14(6-13(16)19(20,21)22)24-18(25-15)26-9-10(8-23-26)17(27)28/h2-9H,1H3,(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475562 (1-[6-Chloro-5-(3-chloro-phenylmethanesulfonyl)-1H-...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C18H12Cl2N4O4S/c19-12-3-1-2-10(4-12)9-29(27,28)16-6-15-14(5-13(16)20)22-18(23-15)24-8-11(7-21-24)17(25)26/h1-8H,9H2,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475564 (1-[6-Chloro-5-(3,4-dichloro-phenylmethanesulfonyl)...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H11Cl3N4O4S/c19-11-2-1-9(3-12(11)20)8-30(28,29)16-5-15-14(4-13(16)21)23-18(24-15)25-7-10(6-22-25)17(26)27/h1-7H,8H2,(H,23,24)(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475568 (1-[5-(2,4-Bis-trifluoromethyl-phenylmethanesulfony...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H11ClF6N4O4S/c21-13-4-14-15(30-18(29-14)31-7-10(6-28-31)17(32)33)5-16(13)36(34,35)8-9-1-2-11(19(22,23)24)3-12(9)20(25,26)27/h1-7H,8H2,(H,29,30)(H,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475542 (1-(5-Ethylsulfonyl-6-trifluoromethyl-1H-benzoimida...) Show SMILES CCS(=O)(=O)c1cc2nc([nH]c2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C14H11F3N4O4S/c1-2-26(24,25)11-4-10-9(3-8(11)14(15,16)17)19-13(20-10)21-6-7(5-18-21)12(22)23/h3-6H,2H2,1H3,(H,19,20)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475543 (1-(5-Ethylsulfonyl-6-trifluoromethoxy-1H-benzoimid...) Show SMILES CCS(=O)(=O)c1cc2nc([nH]c2cc1OC(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C14H11F3N4O5S/c1-2-27(24,25)11-4-9-8(3-10(11)26-14(15,16)17)19-13(20-9)21-6-7(5-18-21)12(22)23/h3-6H,2H2,1H3,(H,19,20)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475549 (1-(5-Benzenesulfonyl-6-trifluoromethyl-1H- | US108...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(cc2[nH]1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H11F3N4O4S/c19-18(20,21)12-6-13-14(7-15(12)30(28,29)11-4-2-1-3-5-11)24-17(23-13)25-9-10(8-22-25)16(26)27/h1-9H,(H,23,24)(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475550 (1-[5-(4-Methoxy-benzenesulfonyl)-6-trifluoromethyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1cc2nc([nH]c2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C19H13F3N4O5S/c1-31-11-2-4-12(5-3-11)32(29,30)16-7-15-14(6-13(16)19(20,21)22)24-18(25-15)26-9-10(8-23-26)17(27)28/h2-9H,1H3,(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475562 (1-[6-Chloro-5-(3-chloro-phenylmethanesulfonyl)-1H-...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C18H12Cl2N4O4S/c19-12-3-1-2-10(4-12)9-29(27,28)16-6-15-14(5-13(16)20)22-18(23-15)24-8-11(7-21-24)17(25)26/h1-8H,9H2,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475564 (1-[6-Chloro-5-(3,4-dichloro-phenylmethanesulfonyl)...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H11Cl3N4O4S/c19-11-2-1-9(3-12(11)20)8-30(28,29)16-5-15-14(4-13(16)21)23-18(24-15)25-7-10(6-22-25)17(26)27/h1-7H,8H2,(H,23,24)(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475568 (1-[5-(2,4-Bis-trifluoromethyl-phenylmethanesulfony...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H11ClF6N4O4S/c21-13-4-14-15(30-18(29-14)31-7-10(6-28-31)17(32)33)5-16(13)36(34,35)8-9-1-2-11(19(22,23)24)3-12(9)20(25,26)27/h1-7H,8H2,(H,29,30)(H,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475401 (1-{5-[3-(2-Chloro-benzyloxy)-phenyl]-1H-benzoimida...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(ccc2[nH]1)-c1cccc(OCc2ccccc2Cl)c1 Show InChI InChI=1S/C24H17ClN4O3/c25-20-7-2-1-4-17(20)14-32-19-6-3-5-15(10-19)16-8-9-21-22(11-16)28-24(27-21)29-13-18(12-26-29)23(30)31/h1-13H,14H2,(H,27,28)(H,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475401 (1-{5-[3-(2-Chloro-benzyloxy)-phenyl]-1H-benzoimida...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(ccc2[nH]1)-c1cccc(OCc2ccccc2Cl)c1 Show InChI InChI=1S/C24H17ClN4O3/c25-20-7-2-1-4-17(20)14-32-19-6-3-5-15(10-19)16-8-9-21-22(11-16)28-24(27-21)29-13-18(12-26-29)23(30)31/h1-13H,14H2,(H,27,28)(H,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475485 (1-(6-Methanesulfonyl-5-trifluoromethyl-1H- | US108...) Show SMILES CS(=O)(=O)c1cc2[nH]c(nc2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C13H9F3N4O4S/c1-25(23,24)10-3-9-8(2-7(10)13(14,15)16)18-12(19-9)20-5-6(4-17-20)11(21)22/h2-5H,1H3,(H,18,19)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475542 (1-(5-Ethylsulfonyl-6-trifluoromethyl-1H-benzoimida...) Show SMILES CCS(=O)(=O)c1cc2nc([nH]c2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C14H11F3N4O4S/c1-2-26(24,25)11-4-10-9(3-8(11)14(15,16)17)19-13(20-10)21-6-7(5-18-21)12(22)23/h3-6H,2H2,1H3,(H,19,20)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475471 (1-(5-Benzenesulfonyl-6-chloro-1H-benzoimidazol-2-y...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H11ClN4O4S/c18-12-6-13-14(7-15(12)27(25,26)11-4-2-1-3-5-11)21-17(20-13)22-9-10(8-19-22)16(23)24/h1-9H,(H,20,21)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.9	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475471 (1-(5-Benzenesulfonyl-6-chloro-1H-benzoimidazol-2-y...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H11ClN4O4S/c18-12-6-13-14(7-15(12)27(25,26)11-4-2-1-3-5-11)21-17(20-13)22-9-10(8-19-22)16(23)24/h1-9H,(H,20,21)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475443 (1-[5-(4-Chloro-phenoxy)-6-trifluoromethyl-1H- | US...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(Oc3ccc(Cl)cc3)c(cc2[nH]1)C(F)(F)F Show InChI InChI=1S/C18H10ClF3N4O3/c19-10-1-3-11(4-2-10)29-15-6-14-13(5-12(15)18(20,21)22)24-17(25-14)26-8-9(7-23-26)16(27)28/h1-8H,(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475494 (1-[6-(Propane-1-sulfonyl)-5-trifluoromethoxy-1H- |...) Show SMILES CCCS(=O)(=O)c1cc2[nH]c(nc2cc1OC(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C15H13F3N4O5S/c1-2-3-28(25,26)12-5-10-9(4-11(12)27-15(16,17)18)20-14(21-10)22-7-8(6-19-22)13(23)24/h4-7H,2-3H2,1H3,(H,20,21)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475480 (1-[6-Chloro-5-(4-fluoro-phenylmethanesulfonyl)-1H-...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(F)cc1 Show InChI InChI=1S/C18H12ClFN4O4S/c19-13-5-14-15(23-18(22-14)24-8-11(7-21-24)17(25)26)6-16(13)29(27,28)9-10-1-3-12(20)4-2-10/h1-8H,9H2,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475481 (1-[6-Chloro-5-(2-chloro-phenylmethanesulfonyl)-1H-...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccccc1Cl Show InChI InChI=1S/C18H12Cl2N4O4S/c19-12-4-2-1-3-10(12)9-29(27,28)16-6-15-14(5-13(16)20)22-18(23-15)24-8-11(7-21-24)17(25)26/h1-8H,9H2,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475488 (1-(6-Methanesulfonyl-5-trifluoromethoxy-1H- | US10...) Show SMILES CS(=O)(=O)c1cc2[nH]c(nc2cc1OC(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C13H9F3N4O5S/c1-26(23,24)10-3-8-7(2-9(10)25-13(14,15)16)18-12(19-8)20-5-6(4-17-20)11(21)22/h2-5H,1H3,(H,18,19)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475490 (1-[5-Chloro-6-(propane-1-sulfonyl)-1H-benzoimidazo...) Show SMILES CCCS(=O)(=O)c1cc2[nH]c(nc2cc1Cl)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C14H13ClN4O4S/c1-2-3-24(22,23)12-5-11-10(4-9(12)15)17-14(18-11)19-7-8(6-16-19)13(20)21/h4-7H,2-3H2,1H3,(H,17,18)(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475492 (1-[6-(Propane-1-sulfonyl)-5-trifluoromethyl-1H- | ...) Show SMILES CCCS(=O)(=O)c1cc2[nH]c(nc2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C15H13F3N4O4S/c1-2-3-27(25,26)12-5-11-10(4-9(12)15(16,17)18)20-14(21-11)22-7-8(6-19-22)13(23)24/h4-7H,2-3H2,1H3,(H,20,21)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475494 (1-[6-(Propane-1-sulfonyl)-5-trifluoromethoxy-1H- |...) Show SMILES CCCS(=O)(=O)c1cc2[nH]c(nc2cc1OC(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C15H13F3N4O5S/c1-2-3-28(25,26)12-5-10-9(4-11(12)27-15(16,17)18)20-14(21-10)22-7-8(6-19-22)13(23)24/h4-7H,2-3H2,1H3,(H,20,21)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475548 (1-[5-(4-Methoxy-phenylsulfanyl)-6-trifluoromethyl-...) Show SMILES COc1ccc(Sc2cc3nc([nH]c3cc2C(F)(F)F)-n2cc(cn2)C(O)=O)cc1 Show InChI InChI=1S/C19H13F3N4O3S/c1-29-11-2-4-12(5-3-11)30-16-7-15-14(6-13(16)19(20,21)22)24-18(25-15)26-9-10(8-23-26)17(27)28/h2-9H,1H3,(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475560 (1-[6-Chloro-5-(2'-cyano-biphenyl-4-ylmethylsulfany...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(SCc3ccc(cc3)-c3ccccc3C#N)c(Cl)cc2[nH]1 Show InChI InChI=1S/C25H16ClN5O2S/c26-20-9-21-22(30-25(29-21)31-13-18(12-28-31)24(32)33)10-23(20)34-14-15-5-7-16(8-6-15)19-4-2-1-3-17(19)11-27/h1-10,12-13H,14H2,(H,29,30)(H,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475565 (1-[6-Chloro-5-(2,6-dichloro-phenylmethanesulfonyl)...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1c(Cl)cccc1Cl Show InChI InChI=1S/C18H11Cl3N4O4S/c19-11-2-1-3-12(20)10(11)8-30(28,29)16-5-15-14(4-13(16)21)23-18(24-15)25-7-9(6-22-25)17(26)27/h1-7H,8H2,(H,23,24)(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475548 (1-[5-(4-Methoxy-phenylsulfanyl)-6-trifluoromethyl-...) Show SMILES COc1ccc(Sc2cc3nc([nH]c3cc2C(F)(F)F)-n2cc(cn2)C(O)=O)cc1 Show InChI InChI=1S/C19H13F3N4O3S/c1-29-11-2-4-12(5-3-11)30-16-7-15-14(6-13(16)19(20,21)22)24-18(25-15)26-9-10(8-23-26)17(27)28/h2-9H,1H3,(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475560 (1-[6-Chloro-5-(2'-cyano-biphenyl-4-ylmethylsulfany...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(SCc3ccc(cc3)-c3ccccc3C#N)c(Cl)cc2[nH]1 Show InChI InChI=1S/C25H16ClN5O2S/c26-20-9-21-22(30-25(29-21)31-13-18(12-28-31)24(32)33)10-23(20)34-14-15-5-7-16(8-6-15)19-4-2-1-3-17(19)11-27/h1-10,12-13H,14H2,(H,29,30)(H,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475565 (1-[6-Chloro-5-(2,6-dichloro-phenylmethanesulfonyl)...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1c(Cl)cccc1Cl Show InChI InChI=1S/C18H11Cl3N4O4S/c19-11-2-1-3-12(20)10(11)8-30(28,29)16-5-15-14(4-13(16)21)23-18(24-15)25-7-9(6-22-25)17(26)27/h1-7H,8H2,(H,23,24)(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475400 (1-{5-[3-(3-Chloro-benzyloxy)-phenyl]-1H-benzoimida...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(ccc2[nH]1)-c1cccc(OCc2cccc(Cl)c2)c1 Show InChI InChI=1S/C24H17ClN4O3/c25-19-5-1-3-15(9-19)14-32-20-6-2-4-16(10-20)17-7-8-21-22(11-17)28-24(27-21)29-13-18(12-26-29)23(30)31/h1-13H,14H2,(H,27,28)(H,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475428 (1-(6-Chloro-5-nitro-1H-benzoimidazol-2-yl)-1H-pyra...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)[N+]([O-])=O Show InChI InChI=1S/C11H6ClN5O4/c12-6-1-7-8(2-9(6)17(20)21)15-11(14-7)16-4-5(3-13-16)10(18)19/h1-4H,(H,14,15)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair

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