Compile Data Set for Download or QSAR

Found 36 hits with Last Name = 'shinchi' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Mus musculus)	BDBM50539339 (CHEMBL4637769) Show SMILES COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(cc3)C(O)=O)c2n1 Show InChI InChI=1S/C16H17N5O5/c1-25-6-7-26-15-19-12(17)11-13(20-15)21(16(24)18-11)8-9-2-4-10(5-3-9)14(22)23/h2-5H,6-8H2,1H3,(H,18,24)(H,22,23)(H2,17,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	252	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539350 (CHEMBL4635551) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@]([H])(O[C@H]4O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@]([H])(O[C@H]6O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O1)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@@H](NC(=O)c1ccc(Cn3c(O)nc4c(N)cc(OCCOC)cc34)cc1)[C@@H]2O |r| Show InChI InChI=1S/C54H78N4O33/c1-78-6-7-79-19-8-20(55)28-21(9-19)58(54(77)57-28)10-17-2-4-18(5-3-17)47(76)56-29-30(65)48-80-22(11-59)41(29)86-49-36(71)31(66)43(24(13-61)81-49)88-51-38(73)33(68)45(26(15-63)83-51)90-53-40(75)35(70)46(27(16-64)85-53)91-52-39(74)34(69)44(25(14-62)84-52)89-50-37(72)32(67)42(87-48)23(12-60)82-50/h2-5,8-9,22-27,29-46,48-53,59-75H,6-7,10-16,55H2,1H3,(H,56,76)(H,57,77)/t22-,23-,24-,25-,26-,27-,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,48-,49-,50-,51-,52-,53-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion preincubated with...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539341 (CHEMBL4632609) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)N[C@H]3C(O)O[C@H](CO)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-26-17(23)14-18(27-21)28(22(34)25-14)8-10-2-4-11(5-3-10)19(32)24-13-16(31)15(30)12(9-29)37-20(13)33/h2-5,12-13,15-16,20,29-31,33H,6-9H2,1H3,(H,24,32)(H,25,34)(H2,23,26,27)/t12-,13-,15+,16-,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	153	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539342 (CHEMBL4641619) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)NC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-25-17(23)13-18(26-21)28(22(34)24-13)8-10-2-4-11(5-3-10)19(33)27-20-16(32)15(31)14(30)12(9-29)37-20/h2-5,12,14-16,20,29-32H,6-9H2,1H3,(H,24,34)(H,27,33)(H2,23,25,26)/t12-,14-,15+,16-,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539343 (CHEMBL4639099) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)NC3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-25-17(23)13-18(26-21)28(22(34)24-13)8-10-2-4-11(5-3-10)19(33)27-20-16(32)15(31)14(30)12(9-29)37-20/h2-5,12,14-16,20,29-32H,6-9H2,1H3,(H,24,34)(H,27,33)(H2,23,25,26)/t12-,14+,15+,16-,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539344 (CHEMBL4647035) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)NC3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-25-17(23)13-18(26-21)28(22(34)24-13)8-10-2-4-11(5-3-10)19(33)27-20-16(32)15(31)14(30)12(9-29)37-20/h2-5,12,14-16,20,29-32H,6-9H2,1H3,(H,24,34)(H,27,33)(H2,23,25,26)/t12-,14-,15+,16+,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	252	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539345 (CHEMBL4645661) Show SMILES [H][C@]1(O[C@@H]2[C@@H](CO)OC(NC(=O)c3ccc(Cn4c(O)nc5c(N)nc(OCCOC)nc45)cc3)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C28H38N6O14/c1-44-6-7-45-27-31-22(29)15-23(32-27)34(28(43)30-15)8-11-2-4-12(5-3-11)24(42)33-25-19(40)18(39)21(14(10-36)46-25)48-26-20(41)17(38)16(37)13(9-35)47-26/h2-5,13-14,16-21,25-26,35-41H,6-10H2,1H3,(H,30,43)(H,33,42)(H2,29,31,32)/t13-,14-,16-,17+,18-,19-,20-,21-,25?,26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	136	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539346 (CHEMBL4641702) Show SMILES [H][C@@]1(O[C@@H]2[C@@H](CO)OC(NC(=O)c3ccc(Cn4c(O)nc5c(N)nc(OCCOC)nc45)cc3)[C@H](O)[C@H]2O)O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C28H38N6O14/c1-44-6-7-45-27-31-22(29)15-23(32-27)34(28(43)30-15)8-11-2-4-12(5-3-11)24(42)33-25-19(40)18(39)21(14(10-36)46-25)48-26-20(41)17(38)16(37)13(9-35)47-26/h2-5,13-14,16-21,25-26,35-41H,6-10H2,1H3,(H,30,43)(H,33,42)(H2,29,31,32)/t13-,14-,16+,17+,18-,19-,20-,21-,25?,26+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539347 (CHEMBL4639831) Show SMILES [H][C@@]12O[C@H](CNC(=O)c3ccc(Cn4c(O)nc5c(N)nc(OCCOC)nc45)cc3)[C@@]([H])(O[C@H]3O[C@H](CO)[C@@]([H])(O[C@H]4O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@]([H])(O[C@H]6O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O1)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O |r| Show InChI InChI=1S/C52H76N6O33/c1-78-6-7-79-51-56-42(53)23-43(57-51)58(52(77)55-23)9-15-2-4-16(5-3-15)44(76)54-8-17-36-24(64)30(70)45(80-17)87-37-18(10-59)82-47(32(72)26(37)66)89-39-20(12-61)84-49(34(74)28(39)68)91-41-22(14-63)85-50(35(75)29(41)69)90-40-21(13-62)83-48(33(73)27(40)67)88-38-19(11-60)81-46(86-36)31(71)25(38)65/h2-5,17-22,24-41,45-50,59-75H,6-14H2,1H3,(H,54,76)(H,55,77)(H2,53,56,57)/t17-,18-,19-,20-,21-,22-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,45-,46-,47-,48-,49-,50-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	128	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539348 (CHEMBL4647802) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@]([H])(O[C@H]4O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@]([H])(O[C@H]6O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O[C@@]8([H])O[C@H](CNC(=O)c9ccc(Cn%10c(O)nc%11c(N)nc(OCCOC)nc%10%11)cc9)[C@@H](O1)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O |r| Show InChI InChI=1S/C58H86N6O38/c1-87-6-7-88-57-62-47(59)25-48(63-57)64(58(86)61-25)9-16-2-4-17(5-3-16)49(85)60-8-18-40-26(71)33(78)50(89-18)97-41-19(10-65)91-52(35(80)28(41)73)99-43-21(12-67)93-54(37(82)30(43)75)101-45-23(14-69)95-56(39(84)32(45)77)102-46-24(15-70)94-55(38(83)31(46)76)100-44-22(13-68)92-53(36(81)29(44)74)98-42-20(11-66)90-51(96-40)34(79)27(42)72/h2-5,18-24,26-46,50-56,65-84H,6-15H2,1H3,(H,60,85)(H,61,86)(H2,59,62,63)/t18-,19-,20-,21-,22-,23-,24-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,50-,51-,52-,53-,54-,55-,56-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	287	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539349 (CHEMBL4636020) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@H](O[C@@]4([H])O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@H](O[C@@]6([H])O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O[C@@]8([H])O[C@H](CNC(=O)c9ccc(Cn%10c(O)nc%11c(N)nc(OCCOC)nc%10%11)cc9)[C@@H](O[C@@]9([H])O[C@H](CO)[C@@H](O1)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O |r| Show InChI InChI=1S/C64H96N6O43/c1-96-6-7-97-63-68-52(65)27-53(69-63)70(64(95)67-27)9-17-2-4-18(5-3-17)54(94)66-8-19-44-28(78)36(86)55(98-19)107-45-20(10-71)100-57(38(88)30(45)80)109-47-22(12-73)102-59(40(90)32(47)82)111-49-24(14-75)104-61(42(92)34(49)84)113-51-26(16-77)105-62(43(93)35(51)85)112-50-25(15-76)103-60(41(91)33(50)83)110-48-23(13-74)101-58(39(89)31(48)81)108-46-21(11-72)99-56(106-44)37(87)29(46)79/h2-5,19-26,28-51,55-62,71-93H,6-16H2,1H3,(H,66,94)(H,67,95)(H2,65,68,69)/t19-,20-,21-,22-,23-,24-,25-,26-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,55-,56-,57-,58-,59-,60-,61-,62-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	132	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539350 (CHEMBL4635551) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@]([H])(O[C@H]4O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@]([H])(O[C@H]6O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O1)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@@H](NC(=O)c1ccc(Cn3c(O)nc4c(N)cc(OCCOC)cc34)cc1)[C@@H]2O |r| Show InChI InChI=1S/C54H78N4O33/c1-78-6-7-79-19-8-20(55)28-21(9-19)58(54(77)57-28)10-17-2-4-18(5-3-17)47(76)56-29-30(65)48-80-22(11-59)41(29)86-49-36(71)31(66)43(24(13-61)81-49)88-51-38(73)33(68)45(26(15-63)83-51)90-53-40(75)35(70)46(27(16-64)85-53)91-52-39(74)34(69)44(25(14-62)84-52)89-50-37(72)32(67)42(87-48)23(12-60)82-50/h2-5,8-9,22-27,29-46,48-53,59-75H,6-7,10-16,55H2,1H3,(H,56,76)(H,57,77)/t22-,23-,24-,25-,26-,27-,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,48-,49-,50-,51-,52-,53-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539351 (CHEMBL4635169) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@]([H])(O[C@H]4O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@H](O[C@@]6([H])O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O[C@@]8([H])O[C@H](CO)[C@@H](O1)[C@@H](NC(=O)c1ccc(Cn9c(O)nc%10c(N)cc(OCCOC)cc9%10)cc1)[C@@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O |r| Show InChI InChI=1S/C60H88N4O38/c1-87-6-7-88-20-8-21(61)30-22(9-20)64(60(86)63-30)10-18-2-4-19(5-3-18)52(85)62-31-32(72)53-89-23(11-65)45(31)96-54-39(79)33(73)47(25(13-67)90-54)98-56-41(81)35(75)49(27(15-69)92-56)100-58-43(83)37(77)51(29(17-71)94-58)102-59-44(84)38(78)50(28(16-70)95-59)101-57-42(82)36(76)48(26(14-68)93-57)99-55-40(80)34(74)46(97-53)24(12-66)91-55/h2-5,8-9,23-29,31-51,53-59,65-84H,6-7,10-17,61H2,1H3,(H,62,85)(H,63,86)/t23-,24-,25-,26-,27-,28-,29-,31+,32+,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,53-,54-,55-,56-,57-,58-,59-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539352 (CHEMBL4636482) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@H](O[C@@]4([H])O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@H](O[C@@]6([H])O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O[C@@]8([H])O[C@H](CO)[C@@H](O[C@@]9([H])O[C@H](CO)[C@@H](O1)[C@H](O)[C@H]9O)[C@@H](NC(=O)c1ccc(Cn9c(O)nc%10c(N)nc(OCCOC)nc9%10)cc1)[C@@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O |r| Show InChI InChI=1S/C64H96N6O43/c1-96-6-7-97-63-68-52(65)28-53(69-63)70(64(95)67-28)8-17-2-4-18(5-3-17)54(94)66-27-29(79)55-98-19(9-71)44(27)106-56-37(87)30(80)46(21(11-73)99-56)108-58-39(89)32(82)48(23(13-75)101-58)110-60-41(91)34(84)50(25(15-77)103-60)112-62-43(93)36(86)51(26(16-78)105-62)113-61-42(92)35(85)49(24(14-76)104-61)111-59-40(90)33(83)47(22(12-74)102-59)109-57-38(88)31(81)45(107-55)20(10-72)100-57/h2-5,19-27,29-51,55-62,71-93H,6-16H2,1H3,(H,66,94)(H,67,95)(H2,65,68,69)/t19-,20-,21-,22-,23-,24-,25-,26-,27+,29+,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,55-,56-,57-,58-,59-,60-,61-,62-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	107	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539339 (CHEMBL4637769) Show SMILES COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(cc3)C(O)=O)c2n1 Show InChI InChI=1S/C16H17N5O5/c1-25-6-7-26-15-19-12(17)11-13(20-15)21(16(24)18-11)8-9-2-4-10(5-3-9)14(22)23/h2-5H,6-8H2,1H3,(H,18,24)(H,22,23)(H2,17,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	434	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539340 (CHEMBL4640564) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)N[C@H]3C(O)O[C@H](CO)[C@@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-26-17(23)14-18(27-21)28(22(34)25-14)8-10-2-4-11(5-3-10)19(32)24-13-16(31)15(30)12(9-29)37-20(13)33/h2-5,12-13,15-16,20,29-31,33H,6-9H2,1H3,(H,24,32)(H,25,34)(H2,23,26,27)/t12-,13-,15-,16-,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	239	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539341 (CHEMBL4632609) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)N[C@H]3C(O)O[C@H](CO)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-26-17(23)14-18(27-21)28(22(34)25-14)8-10-2-4-11(5-3-10)19(32)24-13-16(31)15(30)12(9-29)37-20(13)33/h2-5,12-13,15-16,20,29-31,33H,6-9H2,1H3,(H,24,32)(H,25,34)(H2,23,26,27)/t12-,13-,15+,16-,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539342 (CHEMBL4641619) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)NC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-25-17(23)13-18(26-21)28(22(34)24-13)8-10-2-4-11(5-3-10)19(33)27-20-16(32)15(31)14(30)12(9-29)37-20/h2-5,12,14-16,20,29-32H,6-9H2,1H3,(H,24,34)(H,27,33)(H2,23,25,26)/t12-,14-,15+,16-,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	198	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539343 (CHEMBL4639099) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)NC3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-25-17(23)13-18(26-21)28(22(34)24-13)8-10-2-4-11(5-3-10)19(33)27-20-16(32)15(31)14(30)12(9-29)37-20/h2-5,12,14-16,20,29-32H,6-9H2,1H3,(H,24,34)(H,27,33)(H2,23,25,26)/t12-,14+,15+,16-,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	258	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539344 (CHEMBL4647035) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)NC3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-25-17(23)13-18(26-21)28(22(34)24-13)8-10-2-4-11(5-3-10)19(33)27-20-16(32)15(31)14(30)12(9-29)37-20/h2-5,12,14-16,20,29-32H,6-9H2,1H3,(H,24,34)(H,27,33)(H2,23,25,26)/t12-,14-,15+,16+,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	303	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539345 (CHEMBL4645661) Show SMILES [H][C@]1(O[C@@H]2[C@@H](CO)OC(NC(=O)c3ccc(Cn4c(O)nc5c(N)nc(OCCOC)nc45)cc3)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C28H38N6O14/c1-44-6-7-45-27-31-22(29)15-23(32-27)34(28(43)30-15)8-11-2-4-12(5-3-11)24(42)33-25-19(40)18(39)21(14(10-36)46-25)48-26-20(41)17(38)16(37)13(9-35)47-26/h2-5,13-14,16-21,25-26,35-41H,6-10H2,1H3,(H,30,43)(H,33,42)(H2,29,31,32)/t13-,14-,16-,17+,18-,19-,20-,21-,25?,26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539346 (CHEMBL4641702) Show SMILES [H][C@@]1(O[C@@H]2[C@@H](CO)OC(NC(=O)c3ccc(Cn4c(O)nc5c(N)nc(OCCOC)nc45)cc3)[C@H](O)[C@H]2O)O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C28H38N6O14/c1-44-6-7-45-27-31-22(29)15-23(32-27)34(28(43)30-15)8-11-2-4-12(5-3-11)24(42)33-25-19(40)18(39)21(14(10-36)46-25)48-26-20(41)17(38)16(37)13(9-35)47-26/h2-5,13-14,16-21,25-26,35-41H,6-10H2,1H3,(H,30,43)(H,33,42)(H2,29,31,32)/t13-,14-,16+,17+,18-,19-,20-,21-,25?,26+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539347 (CHEMBL4639831) Show SMILES [H][C@@]12O[C@H](CNC(=O)c3ccc(Cn4c(O)nc5c(N)nc(OCCOC)nc45)cc3)[C@@]([H])(O[C@H]3O[C@H](CO)[C@@]([H])(O[C@H]4O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@]([H])(O[C@H]6O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O1)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O |r| Show InChI InChI=1S/C52H76N6O33/c1-78-6-7-79-51-56-42(53)23-43(57-51)58(52(77)55-23)9-15-2-4-16(5-3-15)44(76)54-8-17-36-24(64)30(70)45(80-17)87-37-18(10-59)82-47(32(72)26(37)66)89-39-20(12-61)84-49(34(74)28(39)68)91-41-22(14-63)85-50(35(75)29(41)69)90-40-21(13-62)83-48(33(73)27(40)67)88-38-19(11-60)81-46(86-36)31(71)25(38)65/h2-5,17-22,24-41,45-50,59-75H,6-14H2,1H3,(H,54,76)(H,55,77)(H2,53,56,57)/t17-,18-,19-,20-,21-,22-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,45-,46-,47-,48-,49-,50-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539348 (CHEMBL4647802) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@]([H])(O[C@H]4O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@]([H])(O[C@H]6O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O[C@@]8([H])O[C@H](CNC(=O)c9ccc(Cn%10c(O)nc%11c(N)nc(OCCOC)nc%10%11)cc9)[C@@H](O1)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O |r| Show InChI InChI=1S/C58H86N6O38/c1-87-6-7-88-57-62-47(59)25-48(63-57)64(58(86)61-25)9-16-2-4-17(5-3-16)49(85)60-8-18-40-26(71)33(78)50(89-18)97-41-19(10-65)91-52(35(80)28(41)73)99-43-21(12-67)93-54(37(82)30(43)75)101-45-23(14-69)95-56(39(84)32(45)77)102-46-24(15-70)94-55(38(83)31(46)76)100-44-22(13-68)92-53(36(81)29(44)74)98-42-20(11-66)90-51(96-40)34(79)27(42)72/h2-5,18-24,26-46,50-56,65-84H,6-15H2,1H3,(H,60,85)(H,61,86)(H2,59,62,63)/t18-,19-,20-,21-,22-,23-,24-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,50-,51-,52-,53-,54-,55-,56-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	153	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539349 (CHEMBL4636020) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@H](O[C@@]4([H])O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@H](O[C@@]6([H])O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O[C@@]8([H])O[C@H](CNC(=O)c9ccc(Cn%10c(O)nc%11c(N)nc(OCCOC)nc%10%11)cc9)[C@@H](O[C@@]9([H])O[C@H](CO)[C@@H](O1)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O |r| Show InChI InChI=1S/C64H96N6O43/c1-96-6-7-97-63-68-52(65)27-53(69-63)70(64(95)67-27)9-17-2-4-18(5-3-17)54(94)66-8-19-44-28(78)36(86)55(98-19)107-45-20(10-71)100-57(38(88)30(45)80)109-47-22(12-73)102-59(40(90)32(47)82)111-49-24(14-75)104-61(42(92)34(49)84)113-51-26(16-77)105-62(43(93)35(51)85)112-50-25(15-76)103-60(41(91)33(50)83)110-48-23(13-74)101-58(39(89)31(48)81)108-46-21(11-72)99-56(106-44)37(87)29(46)79/h2-5,19-26,28-51,55-62,71-93H,6-16H2,1H3,(H,66,94)(H,67,95)(H2,65,68,69)/t19-,20-,21-,22-,23-,24-,25-,26-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,55-,56-,57-,58-,59-,60-,61-,62-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	108	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539350 (CHEMBL4635551) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@]([H])(O[C@H]4O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@]([H])(O[C@H]6O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O1)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@@H](NC(=O)c1ccc(Cn3c(O)nc4c(N)cc(OCCOC)cc34)cc1)[C@@H]2O |r| Show InChI InChI=1S/C54H78N4O33/c1-78-6-7-79-19-8-20(55)28-21(9-19)58(54(77)57-28)10-17-2-4-18(5-3-17)47(76)56-29-30(65)48-80-22(11-59)41(29)86-49-36(71)31(66)43(24(13-61)81-49)88-51-38(73)33(68)45(26(15-63)83-51)90-53-40(75)35(70)46(27(16-64)85-53)91-52-39(74)34(69)44(25(14-62)84-52)89-50-37(72)32(67)42(87-48)23(12-60)82-50/h2-5,8-9,22-27,29-46,48-53,59-75H,6-7,10-16,55H2,1H3,(H,56,76)(H,57,77)/t22-,23-,24-,25-,26-,27-,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,48-,49-,50-,51-,52-,53-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539351 (CHEMBL4635169) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@]([H])(O[C@H]4O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@H](O[C@@]6([H])O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O[C@@]8([H])O[C@H](CO)[C@@H](O1)[C@@H](NC(=O)c1ccc(Cn9c(O)nc%10c(N)cc(OCCOC)cc9%10)cc1)[C@@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O |r| Show InChI InChI=1S/C60H88N4O38/c1-87-6-7-88-20-8-21(61)30-22(9-20)64(60(86)63-30)10-18-2-4-19(5-3-18)52(85)62-31-32(72)53-89-23(11-65)45(31)96-54-39(79)33(73)47(25(13-67)90-54)98-56-41(81)35(75)49(27(15-69)92-56)100-58-43(83)37(77)51(29(17-71)94-58)102-59-44(84)38(78)50(28(16-70)95-59)101-57-42(82)36(76)48(26(14-68)93-57)99-55-40(80)34(74)46(97-53)24(12-66)91-55/h2-5,8-9,23-29,31-51,53-59,65-84H,6-7,10-17,61H2,1H3,(H,62,85)(H,63,86)/t23-,24-,25-,26-,27-,28-,29-,31+,32+,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,53-,54-,55-,56-,57-,58-,59-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539352 (CHEMBL4636482) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@H](O[C@@]4([H])O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@H](O[C@@]6([H])O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O[C@@]8([H])O[C@H](CO)[C@@H](O[C@@]9([H])O[C@H](CO)[C@@H](O1)[C@H](O)[C@H]9O)[C@@H](NC(=O)c1ccc(Cn9c(O)nc%10c(N)nc(OCCOC)nc9%10)cc1)[C@@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O |r| Show InChI InChI=1S/C64H96N6O43/c1-96-6-7-97-63-68-52(65)28-53(69-63)70(64(95)67-28)8-17-2-4-18(5-3-17)54(94)66-27-29(79)55-98-19(9-71)44(27)106-56-37(87)30(80)46(21(11-73)99-56)108-58-39(89)32(82)48(23(13-75)101-58)110-60-41(91)34(84)50(25(15-77)103-60)112-62-43(93)36(86)51(26(16-78)105-62)113-61-42(92)35(85)49(24(14-76)104-61)111-59-40(90)33(83)47(22(12-74)102-59)109-57-38(88)31(81)45(107-55)20(10-72)100-57/h2-5,19-27,29-51,55-62,71-93H,6-16H2,1H3,(H,66,94)(H,67,95)(H2,65,68,69)/t19-,20-,21-,22-,23-,24-,25-,26-,27+,29+,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,55-,56-,57-,58-,59-,60-,61-,62-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539339 (CHEMBL4637769) Show SMILES COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(cc3)C(O)=O)c2n1 Show InChI InChI=1S/C16H17N5O5/c1-25-6-7-26-15-19-12(17)11-13(20-15)21(16(24)18-11)8-9-2-4-10(5-3-9)14(22)23/h2-5H,6-8H2,1H3,(H,18,24)(H,22,23)(H2,17,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 6 h...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539342 (CHEMBL4641619) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)NC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-25-17(23)13-18(26-21)28(22(34)24-13)8-10-2-4-11(5-3-10)19(33)27-20-16(32)15(31)14(30)12(9-29)37-20/h2-5,12,14-16,20,29-32H,6-9H2,1H3,(H,24,34)(H,27,33)(H2,23,25,26)/t12-,14-,15+,16-,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 6 h...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539345 (CHEMBL4645661) Show SMILES [H][C@]1(O[C@@H]2[C@@H](CO)OC(NC(=O)c3ccc(Cn4c(O)nc5c(N)nc(OCCOC)nc45)cc3)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C28H38N6O14/c1-44-6-7-45-27-31-22(29)15-23(32-27)34(28(43)30-15)8-11-2-4-12(5-3-11)24(42)33-25-19(40)18(39)21(14(10-36)46-25)48-26-20(41)17(38)16(37)13(9-35)47-26/h2-5,13-14,16-21,25-26,35-41H,6-10H2,1H3,(H,30,43)(H,33,42)(H2,29,31,32)/t13-,14-,16-,17+,18-,19-,20-,21-,25?,26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	277	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 6 h...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539350 (CHEMBL4635551) Show SMILES [H][C@@]12O[C@H](CO)[C@@H](O[C@@]3([H])O[C@H](CO)[C@@]([H])(O[C@H]4O[C@H](CO)[C@@]([H])(O[C@H]5O[C@H](CO)[C@@]([H])(O[C@H]6O[C@H](CO)[C@@]([H])(O[C@H]7O[C@H](CO)[C@@H](O1)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@@H](NC(=O)c1ccc(Cn3c(O)nc4c(N)cc(OCCOC)cc34)cc1)[C@@H]2O |r| Show InChI InChI=1S/C54H78N4O33/c1-78-6-7-79-19-8-20(55)28-21(9-19)58(54(77)57-28)10-17-2-4-18(5-3-17)47(76)56-29-30(65)48-80-22(11-59)41(29)86-49-36(71)31(66)43(24(13-61)81-49)88-51-38(73)33(68)45(26(15-63)83-51)90-53-40(75)35(70)46(27(16-64)85-53)91-52-39(74)34(69)44(25(14-62)84-52)89-50-37(72)32(67)42(87-48)23(12-60)82-50/h2-5,8-9,22-27,29-46,48-53,59-75H,6-7,10-16,55H2,1H3,(H,56,76)(H,57,77)/t22-,23-,24-,25-,26-,27-,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,48-,49-,50-,51-,52-,53-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	186	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 6 h...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539339 (CHEMBL4637769) Show SMILES COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(cc3)C(O)=O)c2n1 Show InChI InChI=1S/C16H17N5O5/c1-25-6-7-26-15-19-12(17)11-13(20-15)21(16(24)18-11)8-9-2-4-10(5-3-9)14(22)23/h2-5H,6-8H2,1H3,(H,18,24)(H,22,23)(H2,17,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion preincubated with...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539342 (CHEMBL4641619) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)NC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-25-17(23)13-18(26-21)28(22(34)24-13)8-10-2-4-11(5-3-10)19(33)27-20-16(32)15(31)14(30)12(9-29)37-20/h2-5,12,14-16,20,29-32H,6-9H2,1H3,(H,24,34)(H,27,33)(H2,23,25,26)/t12-,14-,15+,16-,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	909	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion preincubated with...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539345 (CHEMBL4645661) Show SMILES [H][C@]1(O[C@@H]2[C@@H](CO)OC(NC(=O)c3ccc(Cn4c(O)nc5c(N)nc(OCCOC)nc45)cc3)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C28H38N6O14/c1-44-6-7-45-27-31-22(29)15-23(32-27)34(28(43)30-15)8-11-2-4-12(5-3-11)24(42)33-25-19(40)18(39)21(14(10-36)46-25)48-26-20(41)17(38)16(37)13(9-35)47-26/h2-5,13-14,16-21,25-26,35-41H,6-10H2,1H3,(H,30,43)(H,33,42)(H2,29,31,32)/t13-,14-,16-,17+,18-,19-,20-,21-,25?,26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	585	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion preincubated with...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mus musculus)	BDBM50539340 (CHEMBL4640564) Show SMILES COCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)N[C@H]3C(O)O[C@H](CO)[C@@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C22H28N6O9/c1-35-6-7-36-21-26-17(23)14-18(27-21)28(22(34)25-14)8-10-2-4-11(5-3-10)19(32)24-13-16(31)15(30)12(9-29)37-20(13)33/h2-5,12-13,15-16,20,29-31,33H,6-9H2,1H3,(H,24,32)(H,25,34)(H2,23,26,27)/t12-,13-,15-,16-,20?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	234	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126840 BindingDB Entry DOI: 10.7270/Q2QR51NJ
					More data for this Ligand-Target Pair