Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM50554673![]() (CHEMBL4760204) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human)) | BDBM50436447![]() (CHEMBL2397162) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human His6-tagged full length PRL3 assessed as inhibition of DiFMUP dephosphorylation | Bioorg Med Chem Lett 23: 3769-74 (2013) Article DOI: 10.1016/j.bmcl.2013.04.092 BindingDB Entry DOI: 10.7270/Q2QR4ZHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human)) | BDBM50184288![]() (5-(2-(2-bromobenzyloxy)-5-bromobenzylidene)-2-thio...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human His6-tagged full length PRL3 assessed as inhibition of DiFMUP dephosphorylation | Bioorg Med Chem Lett 23: 3769-74 (2013) Article DOI: 10.1016/j.bmcl.2013.04.092 BindingDB Entry DOI: 10.7270/Q2QR4ZHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM50554676![]() (CHEMBL4788427) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM50554672![]() (CHEMBL4758139) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM50554674![]() (CHEMBL4777323) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM50554675![]() (CHEMBL4792348) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM50554677![]() (CHEMBL4765111) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01451 BindingDB Entry DOI: 10.7270/Q2W38105 | |||||||||||
More data for this Ligand-Target Pair |