Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human)) | BDBM50316411 (CHEMBL1094578 | gymnochrome F) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Harbor Branch Oceanographic Institute at Florida Atlantic University Curated by ChEMBL | Assay Description Inhibition of MCL1 binding to Bak by FRET assay | J Nat Prod 73: 712-5 (2010) Article DOI: 10.1021/np900526y BindingDB Entry DOI: 10.7270/Q2VQ32TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50316410 (CHEMBL1094577 | gymnochrome E) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Harbor Branch Oceanographic Institute at Florida Atlantic University Curated by ChEMBL | Assay Description Inhibition of human HDAC1 assessed as [3H]acetate release after 90 mins by scintillation counting | J Nat Prod 73: 712-5 (2010) Article DOI: 10.1021/np900526y BindingDB Entry DOI: 10.7270/Q2VQ32TB | |||||||||||
More data for this Ligand-Target Pair |